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Novel gene therapy can improve symptoms of Bubble Boy disease in young adults

Adolescents and young adults with a severe inherited immunodeficiency disorder improved following treatment with novel gene therapy developed at St. Jude Children's Research Hospital and at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. The results of this study appear today in the journal Science Translational Medicine.

21 Apr 2016

Single dose of intraoperative radiotherapy effective for early stage breast cancer patients

In the South East of England, a patient experience study of 18 early stage breast cancer patients who opted for single dose intraoperative radiotherapy, found positive patient reported outcomes for this alternative to standard daily external beam radiotherapy.

21 Apr 2016

Patients who survived life-threatening illness in ICU at increased risk for psychiatric symptoms

Results of a multi-institutional national study of nearly 700 people who survived life-threatening illness with a stay in an intensive care unit (ICU) suggest that a substantial majority of them are at high risk for persistent depression, anxiety and post-traumatic stress disorder — especially if they are female, young and unemployed.

21 Apr 2016

Scientists develop new drug for life-threatening lung disease treatment

Researchers are developing a new drug to treat life-threatening lung damage and breathing problems in people with severe infections like pneumonia, those undergoing certain cancer treatments and premature infants with underdeveloped, injury prone lungs.

20 Apr 2016

New mouse model to aid in development of antiviral compounds, vaccines against Zika virus

Researchers at the University of Wisconsin-Madison School of Veterinary Medicine have developed one of the first mouse models for the study of Zika virus. The model will allow researchers to better understand how the virus causes disease and aid in the development of antiviral compounds and vaccines.

20 Apr 2016

Study shows pulmonary alveolar proteinosis can be cured by single transfer of monocytes

Researchers from VIB-UGent reveal that adult circulating monocytes that get access to the macrophage niche in the liver or the lung can acquire identical tissue-specific macrophage functions and self-maintenance capacities as macrophages of embryonic origin.

20 Apr 2016

Immunotherapy drug pembrolizumab shrinks tumors in patients with Merkel cell carcinoma

In a clinical trial of the immunotherapy drug pembrolizumab, half of 25 patients with a rare type of virus-linked skin cancer called Merkel cell carcinoma experienced substantial tumor shrinkage lasting nearly three times as long, on average, than with conventional chemotherapy.

20 Apr 2016

Drexel study provides new insight into future treatment of breathing disorders

Bringing a steady supply of fresh air to the lungs can seem like a simple task, but breathing is a careful orchestration of brain and body.

20 Apr 2016

NObreath®: the essential tool for World Asthma Day

Asthma UK found 120,000 asthma sufferers at risk from wrongly prescribed medication, while NICE found 30% of people with asthma suspected to be misdiagnosed.

From Bedfont® Scientific Ltd 20 Apr 2016

Researchers identify biological pathway that explains why current asthma therapies fail in many cases

Asthma is an enormous public health problem that continues to grow larger, in part because scientists don't fully understand how it is caused. Existing therapies don't cure the disease and often don't even significantly alleviate the symptoms. Now, scientists from the Perelman School of Medicine at the University of Pennsylvania and Rutgers University have identified a biological pathway that potentially explains why current asthma therapies don't work well in many cases—and might be targeted to help those patients.

19 Apr 2016

Radiotherapy needs likely to increase in all European countries by 2025

The demand for radiotherapy across all European countries will increase by an average of 16% between 2012 and 2025, with the highest expected increase being for prostate cancer cases (24%), according to a new study published in Radiotherapy and Oncology.

19 Apr 2016

Study: British adults agree to donate heart, kidney and lungs, but not eyes for transplant

Despite a shortage of corneas for transplant purposes, new research reveals that eyes are the one body part we are least likely to donate.

19 Apr 2016

NanoString launches new nCounter Vantage assays that power 3D Biology experiments in cancer research

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today announced the introduction of nCounter Vantage, a portfolio of assays that power 3D Biology™ experiments in cancer research, including immuno-oncology.

From NanoString Technologies 19 Apr 2016

Fujitsu develops portable breath sensor that can quickly measure concentration of gas components in people's breath

Fujitsu Laboratories Ltd. today announced that it has developed a portable breath sensor that can extract and quickly measure the concentration of only specified gas components, such as ammonia, that are included at low concentrations in people's breath and are suggested to be correlated with lifestyle diseases.

19 Apr 2016

Studies confirm benefit of plasma genotyping to predict treatment outcomes for NSCLC patients

The benefit of plasma genotyping to predict treatment benefit in patients with non-small-cell lung cancer (NSCLC) is confirmed in three studies presented today at the European Lung Cancer Conference (ELCC) 2016 in Geneva, Switzerland. Researchers however warned that plasma tests are unlikely to fully replace tissue biopsies.

18 Apr 2016

Article highlights some of key disparities affecting women of color

Women of color face both racial and gender disparities in the incidence, onset, and outcomes of diseases as diverse as cancer, cardiovascular disease, HIV infection and age-related disability.

18 Apr 2016

LOXO-101 drug shows efficacy with tumor regression in varied types of genetically defined cancer

A phase I study of the drug LOXO-101 appears to significantly reduce tumors in patients with varied types of genetically defined cancer, according to a study led by The University of Texas MD Anderson Cancer Center.

18 Apr 2016

Scientists develop innovative technique to deliver cancer drugs deep into tumour cells

Scientists at Nanyang Technological University (NTU Singapore) have invented a new way to deliver cancer drugs deep into tumour cells.

18 Apr 2016

MicroRNAs circulating in blood could lead to first diagnostic test for asthma

People with asthma have telltale molecules circulating in their blood, say researchers at Penn State College of Medicine. The discovery could lead to the first diagnostic blood test for asthma, as well as more targeted treatments for the condition.

16 Apr 2016

Scientists discover underlying mechanisms of nerve damage

Recent research by Sandra Rieger, Ph.D., of the MDI Biological Laboratory identifying the underlying mechanisms of peripheral neuropathy, or nerve damage, has raised the prospect that drug therapies can be developed for the treatment of this condition, which causes pain, numbness and/or tingling in the hands and feet. The research was published March 28 in the Proceedings of the National Academy of Sciences.

16 Apr 2016

Lungs News and Research

Novel gene therapy can improve symptoms of Bubble Boy disease in young adults

Single dose of intraoperative radiotherapy effective for early stage breast cancer patients

Patients who survived life-threatening illness in ICU at increased risk for psychiatric symptoms

Scientists develop new drug for life-threatening lung disease treatment

New mouse model to aid in development of antiviral compounds, vaccines against Zika virus

Study shows pulmonary alveolar proteinosis can be cured by single transfer of monocytes

Immunotherapy drug pembrolizumab shrinks tumors in patients with Merkel cell carcinoma

Drexel study provides new insight into future treatment of breathing disorders

NObreath®: the essential tool for World Asthma Day

Researchers identify biological pathway that explains why current asthma therapies fail in many cases

Radiotherapy needs likely to increase in all European countries by 2025

Study: British adults agree to donate heart, kidney and lungs, but not eyes for transplant

NanoString launches new nCounter Vantage assays that power 3D Biology experiments in cancer research

Fujitsu develops portable breath sensor that can quickly measure concentration of gas components in people's breath

Studies confirm benefit of plasma genotyping to predict treatment outcomes for NSCLC patients

Article highlights some of key disparities affecting women of color

LOXO-101 drug shows efficacy with tumor regression in varied types of genetically defined cancer

Scientists develop innovative technique to deliver cancer drugs deep into tumour cells

MicroRNAs circulating in blood could lead to first diagnostic test for asthma

Scientists discover underlying mechanisms of nerve damage

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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