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Nuvectis launches Phase 1a dose escalation clinical trial of new cancer drug

Clinical trials have begun for a drug candidate for hard-to-treat cancers, discovered at the University of Edinburgh and licensed by US biopharmaceutical company Nuvectis Pharma, Inc.

15 Sep 2023

Chemotherapy drug could be repurposed to treat fatal heart failure, computer model suggests

A chemotherapy drug used to fight bone-marrow cancer also has the potential to treat and prevent potentially deadly heart failure, a powerful new drug-screening tool developed at UVA Health suggests.

15 Sep 2023

Can upper respiratory tract specimens be used to diagnose Tuberculosis?

The diagnostic accuracy of upper respiratory tract samples for active pulmonary tuberculosis (TB).

15 Sep 2023

Novel amino acid mutations suggest local monkeypox transmission in Guangzhou, China

The monkeypox (mpox) virus has caused worldwide transmission since its initial report in England in early May 2022.

15 Sep 2023

Some cardiac arrest patients revived by CPR have clear memories of experiencing death

Up to an hour after their hearts had stopped, some patients revived by cardiopulmonary resuscitation (CPR) had clear memories afterward of experiencing death and had brain patterns while unconscious linked to thought and memory, report investigators in the journal Resuscitation, published by Elsevier.

14 Sep 2023

N-acetylglucosamine reduces multiple inflammation and neurodegeneration markers in MS patients

UCI researchers have found that a simple sugar, N-acetylglucosamine, reduces multiple inflammation and neurodegeneration markers in people who suffer from multiple sclerosis (MS).

14 Sep 2023

Genetic sequencing shows promise as first-tier newborn screening test

Newborn screening (NBS) is routinely performed across the world using biochemical testing methods. Recent advancements in genetic sequencing are a potential game-changer for newborn screening, swiftly assessing a comprehensive range of monogenic disorders.

14 Sep 2023

New intrauterine device is highly effective in managing postpartum bleeding

A study led by Columbia obstetricians has shown that a new intrauterine device can rapidly control postpartum hemorrhage, a major cause of severe maternal morbidity and death, in real-world situations.

14 Sep 2023

JAX offers a fully validated, clinical whole genome sequencing test

Until quite recently, it was extremely difficult to detect the variants underlying many genetic disorders. In the absence of a defined cause, clinicians have little to guide treatment for those left without a genetic diagnosis, forcing patients and families to embark on a diagnostic odyssey with no guarantee of finding answers.

14 Sep 2023

Combination immunotherapy outperforms durvalumab monotherapy in neoadjuvant NSCLC

Combination immunotherapy with the anti-PD-L1 monoclonal antibody durvalumab and other novel agents outperforms durvalumab alone in the neoadjuvant (pre-surgical) setting for early-stage non-small-cell lung cancer (NSCLC), according to researchers at The University of Texas MD Anderson Cancer Center.

14 Sep 2023

Cardiac arrest survivors recall lucid death experiences

Up to an hour after their hearts had stopped, some patients revived by cardiopulmonary resuscitation (CPR) had clear memories afterward of experiencing death and while unconscious had brain patterns linked to thought and memory.

14 Sep 2023

Research provides key insights into the molecular underpinnings of acute liver injury

In a study published in the journal of Genes & Diseases, a team of researchers from Chonnam National University and the Korea Research Institute of Bioscience and Biotechnology unveiled important insights into liver injury and its underlying molecular mechanisms.

14 Sep 2023

NO-ferroheme behaves as a signaling entity in the vasculature

Although a simple molecule, nitric oxide is an important signal substance that helps to reduce blood pressure by relaxing the blood vessels.

14 Sep 2023

MIT study reveals why immunotherapy doesn't work for all cancer patients

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14 Sep 2023

Harnessing the extraordinary capabilities of bio-nanoantennae to target and kill brain tumors

Researchers have discovered a new way to target and kill cancer cells in hard-to-treat brain tumors using electrically charged molecules to trigger self-destruction, that could be developed into a spray treatment used during surgery.

14 Sep 2023

UT Health San Antonio and UTSA launch first U.S. MD/MS program in medicine and artificial intelligence

The Joe R. and Teresa Lozano Long School of Medicine at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) and the University College at The University of Texas at San Antonio (UTSA) are officially launching the first known program in the United States to combine medicine and artificial intelligence.

14 Sep 2023

Peer-led navigation program improves mental health outcomes for racially and ethnically minoritized veterans

Research scientists led by Johanne Eliacin, PhD, of the U.S. Department of Veterans' Affairs (VA) and Regenstrief Institute, have developed PARTNER-MH, an innovative, peer-led patient navigation program to support racially and ethnically minoritized veterans seeking mental healthcare, regardless of the types of mental health services needed or their mental health diagnoses.

14 Sep 2023

New trial shows promise of combination neoadjuvant immunotherapy for lung cancer

Patients with stage 1–3 non-small cell lung cancer (NSCLC) given a combination immunotherapy prior to surgery (neoadjuvant) had a better major pathological response (10% or less residual cancer) when the cancer was removed than those who took a single immunotherapy agent alone, according to results of a novel multicenter phase 2 NeoCOAST platform trial that included two investigators from the Johns Hopkins Kimmel Cancer Center and its Bloomberg-Kimmel Institute for Cancer Immunotherapy.

14 Sep 2023

The anti-metastatic and anti-proliferation impact of dandelion extract on breast cancer cells

Researchers evaluated the anti-metastatic and anti-proliferative properties of all-trans retinoic acid (ATRA) and dandelion extract in breast cancer cells.

14 Sep 2023

As more patients email doctors, health systems start charging fees

Meg Bakewell, who has cancer and cancer-related heart disease, sometimes emails her primary care physician, oncologist, and cardiologist asking them for medical advice when she experiences urgent symptoms such as pain or shortness of breath.

14 Sep 2023

Medicine News and Research

Nuvectis launches Phase 1a dose escalation clinical trial of new cancer drug

Chemotherapy drug could be repurposed to treat fatal heart failure, computer model suggests

Can upper respiratory tract specimens be used to diagnose Tuberculosis?

Novel amino acid mutations suggest local monkeypox transmission in Guangzhou, China

Some cardiac arrest patients revived by CPR have clear memories of experiencing death

N-acetylglucosamine reduces multiple inflammation and neurodegeneration markers in MS patients

Genetic sequencing shows promise as first-tier newborn screening test

New intrauterine device is highly effective in managing postpartum bleeding

JAX offers a fully validated, clinical whole genome sequencing test

Combination immunotherapy outperforms durvalumab monotherapy in neoadjuvant NSCLC

Cardiac arrest survivors recall lucid death experiences

Research provides key insights into the molecular underpinnings of acute liver injury

NO-ferroheme behaves as a signaling entity in the vasculature

MIT study reveals why immunotherapy doesn't work for all cancer patients

Harnessing the extraordinary capabilities of bio-nanoantennae to target and kill brain tumors

UT Health San Antonio and UTSA launch first U.S. MD/MS program in medicine and artificial intelligence

Peer-led navigation program improves mental health outcomes for racially and ethnically minoritized veterans

New trial shows promise of combination neoadjuvant immunotherapy for lung cancer

The anti-metastatic and anti-proliferation impact of dandelion extract on breast cancer cells

As more patients email doctors, health systems start charging fees

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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