Immune System News and Research

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Macrophage programming is more complex than previously thought

Macrophages are white blood cells that, depending on the signals they get from the immune system, become specialized in either increasing or decreasing inflammation.

25 Aug 2020

Lasting nature of IBD linked to a long-lived immune cell that provokes damaging inflammation

Inflammatory bowel disease (IBD) is a group of intestinal disorders affecting an estimated six to eight million people worldwide.

24 Aug 2020

Researchers identify mechanisms leading to immune 'exhaustion' in severe viral infections

Melbourne researchers have identified mechanisms leading to the functional deterioration of the immune system in response to severe viral infections, such as HIV or COVID-19.

24 Aug 2020

New discovery about STING protein could lead to improved cancer immunotherapies

The immune protein STING has long been noted for helping protect against viruses and tumors by signaling a well-known immune molecule.

24 Aug 2020

Congenital disorder of fat metabolism can cause chronic hyperreaction of the immune system

Scientists at the University of Bonn identify previously unknown disease mechanism. A congenital disorder of the fat metabolism can apparently cause chronic hyperreaction of the immune system.

24 Aug 2020

New cancer vaccine is predicted to be more effective in human trials

Jefferson researchers developing a cancer vaccine to prevent recurrences of gastric, pancreatic, esophageal and colon cancers have added a component that would make the vaccine more effective.

24 Aug 2020

Study: Frequent use of antimicrobial drugs impairs bacterial diversity in saliva

The strongest associations were presented with azithromycin that is used for example to middle ear infections, strep throat and pneumonia.

24 Aug 2020

Study: Fewer types of fungi in the lungs are associated with increased severity of disease in ARDS patients

Many COVID-19 patients develop acute respiratory distress syndrome (ARDS), a life-threatening condition where the lungs cannot provide the body's vital organs with enough oxygen.

24 Aug 2020

Study offers insights into immune reactions in severe COVID-19

Researchers may have come one step closer toward understanding how the immune system contributes to severe COVID-19.

21 Aug 2020

Researchers find clues to successful immune response in the T cells of COVID-19 patients

When news about a novel coronavirus switched from a chronicle of its progress in China to headlines about a worldwide COVID-19 pandemic, Gladstone Institutes scientist Nadia Roan, PhD, was in the midst of publishing several papers on T cells and their role in HIV spread and long-lasting infections.

21 Aug 2020

New injectable drug could offer long-lasting protection from HIV with fewer side effects

Scientists have developed an injectable drug that blocks HIV from entering cells. They say the new drug potentially offers long-lasting protection from the infection with fewer side effects.

21 Aug 2020

Study: Many COVID-19 patients suffer cardiovascular damage even after recovery

One of the most harrowing effects of COVID-19 is severe damage to the lungs, which makes breathing hard or impossible for those who're severely affected.

21 Aug 2020

SARS-CoV-2 ORF9c responsible for immune evasion and efficient infection of host

A recent study by researchers at the Sanford Burnham Prebys Medical Discovery Institute and the University of California San Francisco and published on the preprint server bioRxiv in August 2020 shows that a protein encoded by the subgenomic sequence ORF9c of SARS-CoV-2 is responsible for the low antiviral response in infected humans, enabling the successful replication of the virus in the host.

21 Aug 2020

Macaques show low neutralizing antibody and cellular immune response to SARS-CoV-2

A new study published on the preprint server bioRxiv* in August 2020 presents a cynomolgus macaque model that develops symptomatic SARS-CoV-2 infection in a mild form, with low or no antibody responses, making it suitable to study human responses to vaccines and drugs targeting the virus.

21 Aug 2020

Newly discovered molecule can suppress a wide range of cancers

Scientists at Scripps Research have discovered a molecule that can activate a natural immune-boosting protein called STING.

21 Aug 2020

Using engineered off-the-shelf therapeutic T cells to fight cancer

Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in 'teaching' the body's immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors.

20 Aug 2020

Post-mortem study of dead COVID-19 patients finds lung damage and blood clots

A new post-mortem study of patients who have died from COVID-19 found severe damage to the lungs and signs of blood clotting in major organs.

20 Aug 2020

A metabolic enzyme shows great potential as target for immunotherapies

The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system.

20 Aug 2020

FDA provides update on adverse events associated with breast implants

Today, the U.S. Food and Drug Administration is providing an update on adverse events reported to the Agency related to breast implants, including breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), and systemic signs and symptoms referred to by patients as breast implant illness (BII), which some patients report after receiving breast implants.

20 Aug 2020

Researchers develop vaccine for human herpesvirus 6B

A research group led by Professor MORI Yasuko (of the Division of Clinical Virology, Center for Infectious Diseases, Kobe University Graduate School of Medicine) has revealed that the HHV-6B glycoprotein complex gH/gL/gQ1/gQ2 is an effective vaccine candidate for human herpesvirus 6B (HHV-6B).

20 Aug 2020

Immune System News and Research

Macrophage programming is more complex than previously thought

Lasting nature of IBD linked to a long-lived immune cell that provokes damaging inflammation

Researchers identify mechanisms leading to immune 'exhaustion' in severe viral infections

New discovery about STING protein could lead to improved cancer immunotherapies

Congenital disorder of fat metabolism can cause chronic hyperreaction of the immune system

New cancer vaccine is predicted to be more effective in human trials

Study: Frequent use of antimicrobial drugs impairs bacterial diversity in saliva

Study: Fewer types of fungi in the lungs are associated with increased severity of disease in ARDS patients

Study offers insights into immune reactions in severe COVID-19

Researchers find clues to successful immune response in the T cells of COVID-19 patients

New injectable drug could offer long-lasting protection from HIV with fewer side effects

Study: Many COVID-19 patients suffer cardiovascular damage even after recovery

SARS-CoV-2 ORF9c responsible for immune evasion and efficient infection of host

Macaques show low neutralizing antibody and cellular immune response to SARS-CoV-2

Newly discovered molecule can suppress a wide range of cancers

Using engineered off-the-shelf therapeutic T cells to fight cancer

Post-mortem study of dead COVID-19 patients finds lung damage and blood clots

A metabolic enzyme shows great potential as target for immunotherapies

FDA provides update on adverse events associated with breast implants

Researchers develop vaccine for human herpesvirus 6B

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