Angina News and Research

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Angina is chest pain or discomfort that occurs when an area of your heart muscle doesn't get enough oxygen-rich blood. Angina may feel like pressure or squeezing in your chest. The pain also may occur in your shoulders, arms, neck, jaw, or back. It can feel like indigestion.

CryoLife acquires Hemosphere

CryoLife, Inc., a leading medical device company focused on cardiac and vascular surgery, announced today that it has completed its previously announced acquisition of Hemosphere, Inc.

17 May 2012

VIVUS receives FDA approval for Stendra to treat erectile dysfunction

The U.S. Food and Drug Administration today approved Stendra (avanafil), a new drug to treat erectile dysfunction.

30 Apr 2012

Cardiovascular emergencies may benefit from regionalized systems of care

Experts are proposing a new model of care collaboration to diagnosis, treat and follow patients who present with various emergent cardiovascular conditions which require rapid, resource-intensive care and confer a high risk of mortality, in an article published April 24 in Circulation.

26 Apr 2012

ECG abnormalities associated with increased risk of CHD in older adults

In a study that included elderly men and women without preexisting cardiovascular disease, major and minor electrocardiographic abnormalities were associated with an increased risk of coronary heart disease (CHD) events and improved the prediction of CHD events such as heart attack, beyond traditional cardiovascular risk factors, according to a study in the April 11 issue of JAMA.

12 Apr 2012

Cedars-Sinai Heart Institute performs most adult heart transplants of any U.S. medical center

For the second year in a row, the Cedars-Sinai Heart Institute and Comprehensive Transplant Center performed the most adult heart transplants of any U.S. medical center, according to government statistics.

4 Apr 2012

The Lancet acknowledges world's first bedside genetic test

Developed in Canada and conducted by researchers from the University of Ottawa Heart Institute, in partnership with Spartan Bioscience, the world's first bedside genetic test has received acknowledgment by The Lancet, the world's leading general medical journal.

30 Mar 2012

Out-of-hospital use of GIK as therapy for ACS patients needs to be assessed

Patients experiencing symptoms such as chest pain who received from paramedics an intravenous solution consisting of glucose-insulin-potassium (GIK) had no reduction in the rate of progression to heart attack and no improvement in 30-day survival, although GIK was associated with a lower rate of the composite outcome of cardiac arrest or in-hospital death, according to a study appearing in JAMA.

28 Mar 2012

Non-HDL-C levels appear to increase risk of heart attack or stroke in statin-treated patients

Levels of non-high-density lipoprotein cholesterol (non-HDL-C) among statin-treated patients appears to be associated with the risk of developing a major cardiovascular event, such as a heart attack or stroke, as are levels of low-density lipoprotein cholesterol (LDL-C) and apolipoprotein B, according to a meta-analysis of data from previously published studies appearing in the March 28 issue of JAMA.

28 Mar 2012

Study shows safe and effective protocol for chest pain patients

Rhode Island Hospital physicians report that managing chest pain patients within an emergency department chest pain unit by both emergency medicine staff and cardiologists is safe and effective and may lower the use of stress testing.

27 Mar 2012

Multifaceted intervention improves use of evidence-based medicines

Among patients with acute coronary syndromes (such as heart attack or unstable angina) treated at public hospitals in Brazil, implementation of a multifaceted intervention that included educational materials, checklists and reminders resulted in improvement in the use of evidence-based medicines during the first 24 hours of hospitalization, according to a study appearing in JAMA.

26 Mar 2012

Largest study to date to look at BMC therapy in patients with heart failure

Use of a patient's bone marrow cells for treating chronic ischemic heart failure did not result in improvement on most measures of heart function, according to a study appearing in JAMA. The study is being published early online to coincide with its presentation at the American College of Cardiology's annual scientific sessions.

26 Mar 2012

Cardium commences Generx Phase 3 registration study in myocardial ischemia

Cardium Therapeutics today announced the initiation of the ASPIRE Phase 3 registration study to evaluate the therapeutic effects of Cardium's lead product candidate, Generx (Ad5FGF-4) in patients with myocardial ischemia.

21 Mar 2012

Novartis' Arcapta Neohaler now available in the U.S. for COPD treatment

Novartis Pharmaceuticals Corporation today announced that once-daily Arcapta Neohaler (indacaterol inhalation powder) 75 mcg is now available in the US and in pharmacies nationwide.

20 Mar 2012

Ivabradine could save thousands of heart failure patients

Researchers behind a major trial of Procoralan believe the pill could save 10,000 lives a year in Britain alone. Ivabradine works by slowing the beating of the heart, helping it to pump blood more efficiently.

7 Mar 2012

Baxter commences CD34+ stem cell phase III trial in CMI

Baxter International Inc. announced today that it has initiated a phase III pivotal clinical trial to evaluate the efficacy and safety of adult autologous (an individual's own) CD34+ stem cells to increase exercise capacity in patients with chronic myocardial ischemia (CMI).

From Baxter International Inc. 28 Feb 2012

Stents not more beneficial than medications in stable coronary artery disease: Study

The placement of a stent to repair a narrowed artery in the heart has become routine worldwide. A new analysis of earlier clinical trials shows that inserting a stent has no benefit over standard medical care in treating stable coronary artery disease.

28 Feb 2012

Initial stent implantation does not appear to improve outcomes for patients with stable CAD

A meta-analysis of eight previously published clinical trials suggests that initial stent implantation for patients with stable coronary artery disease is not associated with improved outcomes compared with initial medical therapy for prevention of death, nonfatal heart attacks, unplanned revascularization or angina, according to a study published in the Feb. 27 Archives of Internal Medicine, one of the JAMA/Archives journals.

28 Feb 2012

FDA assigns Priority Review designation to JRD's XARELTO sNDA

Janssen Research & Development, LLC (JRD) announced today that the U.S. Food and Drug Administration (FDA) has assigned a Priority Review designation to the supplemental New Drug Application (sNDA) filed on December 29, 2011 for XARELTO (rivaroxaban), an oral anticoagulant, to reduce the risk of thrombotic cardiovascular events in patients with Acute Coronary Syndrome (ACS).

27 Feb 2012

Women with heart problems at higher cancer risk after Omega-3 and vitamin B supplementation

However, women with a previous history of cardiovascular pathologies seem to have a higher cancer risk after five years of supplementation. The research is published in detail in the Archives of Internal Medicine.

18 Feb 2012

Calcium scoring screening can effectively detect CAD

Heart disease tragically affects almost every family in the United States. It claimed more than 616,000 lives in 2008, the latest year for which statistics are available. Coronary artery disease is the most common type of heart disease and can lead to heart attacks, heart failure, strokes, arrhythmia and angina.

15 Feb 2012