Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

CWRU researcher receives $1.2 million to identify biomarkers for improving MS diagnoses

Case Western Reserve University researcher Farren Briggs was awarded $1.2 million over three years from the National Institute of Neurological Disorders and Stroke at the National Institutes of Health to identify biomarkers to improve the diagnoses of multiple sclerosis, including the ability to monitor disease activity and progression.

10 Jun 2021

QurAlis gears up for clinical development of therapeutic candidate, QRL-101

(BUSINESS WIRE)--QurAlis Corporation, a biotech company developing breakthrough precision medicines for ALS and other genetically validated neurodegenerative diseases, today announced the publication of an article in Cell Reports.

9 Jun 2021

Researchers identify novel gene that controls sleep/wake cycle in mice

That internal nagging feeling that drives you to seek sleep at night and wake in the morning to eat, work, and play, is, it turns out, genetic, and it's not just in people.

9 Jun 2021

Researchers identify genomic cellular map associated with hippocampal sclerosis

A multidisciplinary team led by researchers from the Spanish Research Council identifies the genomic cellular map associated with hippocampal sclerosis, a major histopathological condition of temporal lobe epilepsy.

8 Jun 2021

Brain study may lead to new treatments for neuro-immune conditions

The immune system is the brain's best frenemy. It protects the brain from infection and helps injured tissues heal, but it also causes autoimmune diseases and creates inflammation that drives neurodegeneration.

8 Jun 2021

New technology can explain the effect of genetic factors on brain structure, function

Liang Zhan, assistant professor of electrical and computer engineering at Pitt's Swanson School of Engineering, received a $500,000 CAREER award from the National Science Foundation to develop computational tools that improve our understanding of the human brain.

8 Jun 2021

A single blood-based biomarker can help indicate underlying neurodegeneration

Levels of a protein called neurofilament light chain (NfL) in the blood can identify those who might have neurodegenerative diseases such as Down's syndrome dementia, motor neuron disease (ALS) and frontotemporal dementia, when clinical symptoms are not definitive

7 Jun 2021

Study reveals potential mechanism for how traumatic brain injury leads to neurodegenerative diseases

Scientists have revealed a potential mechanism for how traumatic brain injury leads to neurodegenerative diseases, according to a study in fruit flies, and rat and human brain tissue, published today in eLife.

1 Jun 2021

Study: Specific diet, lifestyle interventions may reverse epigenetic aging in healthy adult males

Aging published "Potential reversal of epigenetic age using a diet and lifestyle intervention: a pilot randomized clinical trial" which reported on a randomized controlled clinical trial conducted among 43 healthy adult males between the ages of 50-72.

28 May 2021

University of Freiburg professor honored for groundbreaking results on the brain’s immune system

The blood-brain barrier is an impenetrable barrier between the circulating blood and the brain established before birth that prevents immune cells from entering the brain from the body's immune system. Thus, the brain has its own immune system with a key actor called microglia.

21 May 2021

Study may lead to new treatments for a wide range of neurological conditions

New research published today sheds important light on how the production of a key protein in the brain is controlled, which could pave the way for new treatments for a wide range of neurological conditions.

19 May 2021

Simple sugar could play a key role in the development of progressive MS

Multiple sclerosis, or MS for short, manifests itself slightly differently in each person - which is why some call it "the disease of a thousand faces."

12 May 2021

Scientists investigate signal necrotic cells that cue phagocytic cells to engulf the dying cell

Just as people keep their houses clean and clutter under control, a crew of cells in the body is in charge of clearing the waste the body generates, including dying cells. The housekeeping cells remove unwanted material by a process called phagocytosis, which literally means 'eating cells.' The housekeepers engulf and ingest the dying cells and break them down to effectively eliminate them.

7 May 2021

Molecular clues explain why some neurons are more susceptible than others in Alzheimer’s disease

In the brain of a person with Alzheimer's disease, neurons degenerate and die, slowly eliminating memories and cognitive skills. However, not all neurons are impacted equally.

7 May 2021

Researchers use gene therapy to prevent learning, memory loss in Alzheimer's mouse model

Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimer's disease (AD), a key step toward eventually testing the approach in humans with the neurodegenerative disease.

5 May 2021

Certain immune cells can cause damage to the aging nervous system, study finds

Aging is the biggest risk factor for perturbation of the nervous system, even in the absence of distinct disease or trauma.

4 May 2021

Low doses of ionizing radiation may be a promising therapy for people with Alzheimer’s disease

Individuals living with severe Alzheimer's disease showed remarkable improvements in behavior and cognition within days of receiving an innovative new treatment that delivered low doses of radiation, a recent Baycrest-Sunnybrook pilot study found.

3 May 2021

Single protein could be a new target for delaying onset of aging symptoms in the brain

It is not every day that scientists come across a phenomenon so fundamental that it is observed across fruit flies, rodents and humans.

29 Apr 2021

Repairing faulty drains could be key to unlocking the potential of Alzheimer's therapies

Experimental Alzheimer's drugs have shown little success in slowing declines in memory and thinking, leaving scientists searching for explanations.

29 Apr 2021

Researchers identify potential therapeutic target to prevent neurodegeneration after a stroke

Researchers with the Peter O'Donnell Jr. Brain Institute at UT Southwestern have identified a new protein implicated in cell death that provides a potential therapeutic target that could prevent or delay the progress of neurodegenerative diseases following a stroke.

27 Apr 2021

Neurodegeneration News and Research

Further Reading

CWRU researcher receives $1.2 million to identify biomarkers for improving MS diagnoses

QurAlis gears up for clinical development of therapeutic candidate, QRL-101

Researchers identify novel gene that controls sleep/wake cycle in mice

Researchers identify genomic cellular map associated with hippocampal sclerosis

Brain study may lead to new treatments for neuro-immune conditions

New technology can explain the effect of genetic factors on brain structure, function

A single blood-based biomarker can help indicate underlying neurodegeneration

Study reveals potential mechanism for how traumatic brain injury leads to neurodegenerative diseases

Study: Specific diet, lifestyle interventions may reverse epigenetic aging in healthy adult males

University of Freiburg professor honored for groundbreaking results on the brain’s immune system

Study may lead to new treatments for a wide range of neurological conditions

Simple sugar could play a key role in the development of progressive MS

Scientists investigate signal necrotic cells that cue phagocytic cells to engulf the dying cell

Molecular clues explain why some neurons are more susceptible than others in Alzheimer’s disease

Researchers use gene therapy to prevent learning, memory loss in Alzheimer's mouse model

Certain immune cells can cause damage to the aging nervous system, study finds

Low doses of ionizing radiation may be a promising therapy for people with Alzheimer’s disease

Single protein could be a new target for delaying onset of aging symptoms in the brain

Repairing faulty drains could be key to unlocking the potential of Alzheimer's therapies

Researchers identify potential therapeutic target to prevent neurodegeneration after a stroke

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