Transplant News and Research

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Antibody response trajectories among solid organ transplant recipients in association with mycophenolate mofetil administration

Researchers explored the trajectory of antibody (Ab) titers after coronavirus disease 2019 (COVID-19) vaccination among solid organ transplant recipients (SOTs) with or without mycophenolate mofetil (MMF), or withdrawn from MMF.

11 Oct 2022

Study opens up new approaches for treating fatty liver disease

A study group at MedUni Vienna has identified a regulatory loop controlled by leptin, by which this adipocyte-derived hormone regulates hepatic lipid metabolism via the autonomic nervous system.

11 Oct 2022

Chronic liver disease in COVID-19 patients

A recent study summarizes the clinical outcomes of COVID-19 patients with chronic liver disease.

10 Oct 2022

Researchers create a clinical scoring system to predict viable viral shedding after COVID-19 infection

A recent study published in the Journal of Clinical Virology developed an individualized scoring system to predict the shedding of viable SARS-CoV-2 from COVID-19 positive patients, which would help to determine personalized isolation strategies.

6 Oct 2022

Research may lead to safer ways to care for patients impacted by blood clots

A nanoparticle therapy developed by investigators at University Hospitals (UH) and Case Western Reserve University targets overactive neutrophils, a specific kind of white blood cell, to prevent almost all types of blood clots while causing no increased risk for bleeding.

30 Sep 2022

Patients with scleroderma have reduced levels of Cathepsin L

Much of the research on scleroderma, a connective tissue disease that causes scarring, or fibrosis, has focused on the increased number of proteins promoting fibrosis in these patients. A Medical University of South Carolina (MUSC) research team took a different tact and measured the levels of an antifibrotic protein, Cathepsin L, in these patients.

30 Sep 2022

Exploring remdesivir resistance in COVID-19-infected transplant recipients

In a new study, researchers assessed the remdesivir resistance developed in coronavirus disease 2019 (COVID-19)-infected transplant recipients.

29 Sep 2022

UArizona researchers discover new protein that is responsible for controlling cell growth in yeasts

Like bacteria, yeasts are found everywhere, even in and around our bodies. And, as with bacteria, you can become infected by yeasts and become ill. Yeasts infect about 150 million people a year and kill about 1.7 million, especially those who are immunocompromised.

28 Sep 2022

mRNA boosters associated with decreased odds of hospitalization compared with the mRNA vaccine primary series alone

Researchers assessed the chances of COVID-19 hospitalization after three versus two mRNA vaccine doses.

28 Sep 2022

High-tech lab in Nigeria could be a game changer in tackling emerging and re-emerging diseases

Nigeria's Oligo synthesizer laboratory, the first in West Africa, could be a game changer in tackling emerging and re-emerging diseases in the region if harnessed to its full potential, laboratory scientists have said.

27 Sep 2022

Transplantation tolerance associated with conventional T cells’ susceptibility to Treg suppression

Patients who receive organ transplants must take powerful medications to prevent the immune system from rejecting the organ.

27 Sep 2022

Study offers support for increasing the use of living donor liver transplantation in Western countries

Demand for donor livers for transplant patients outstrips supply with over 15% of waitlist patients dying after a year.

26 Sep 2022

Study finds remdesivir-resistant version of COVID-19 in renal transplant recipients

Recent studies have shown that patients with weakened immune systems—which enables the virus that causes COVID-19 to remain longer in the body, copy itself, and continually change—may enable the development of new, slightly different versions of the virus (variants).

26 Sep 2022

Metal compounds could be the solution for drug-resistant fungal infections

University of Queensland researchers say metal compounds could be the answer to the growing problem of drug-resistant fungal infections.

26 Sep 2022

Embedded bias: How medical records sow discrimination

David Confer, a bicyclist and an audio technician, told his doctor he "used to be Ph.D. level" during a 2019 appointment in Washington, D.C. Confer, then 50, was speaking figuratively: He was experiencing brain fog — a symptom of his liver problems. But did his doctor take him seriously? Now, after his death, Confer's partner, Cate Cohen, doesn't think so.

26 Sep 2022

The impact of sleep fragmentation on the clonal diversity of immune cells and the genetic aging of the hematopoietic system

A new study shows that sleep does much more, regulating the normal production of blood cells. This finding underlines how essential a healthy sleep routine is for a normal life.

26 Sep 2022

Patient receives Pacific Northwest's first donation-after-circulatory-death heart transplant

On Aug. 11, LifeCenter Northwest, the Organ Procurement Organization for Washington, and UW Medicine's heart transplant team together facilitated the Pacific Northwest's first donation-after-circulatory-death (DCD) heart transplant.

23 Sep 2022

Cleveland Clinic’s ROBIN center may pave way for more effective radiation, immunotherapy treatments

Cleveland Clinic received a $7.9 million five-year grant from the National Cancer Institute at the National Institutes of Health to form one of three national centers as part of the newly established Radiation Oncology-Biology Integration Network (ROBIN).

22 Sep 2022

New board members bring significant leadership experience in the biotech sector

Aspect Biosystems, a biotechnology company pioneering the development of bioprinted tissue therapeutics to transform how we treat disease, is pleased to announce the appointment of three new members to its Board of Directors: Dr. Nancy Krieger, Dr. Don Haut, and Dr. Devyn Smith.

From Aspect Biosystems 22 Sep 2022

New modeling system identifies potential therapeutics for autosomal recessive polycystic kidney disease

Organoids-;lab grown cells or tissues that resemble organs-;serve as a new tool for disease modeling, but researchers often have difficulty replicating the biophysical conditions in which the organs operate within the body.

22 Sep 2022

Transplant News and Research

Antibody response trajectories among solid organ transplant recipients in association with mycophenolate mofetil administration

Study opens up new approaches for treating fatty liver disease

Chronic liver disease in COVID-19 patients

Researchers create a clinical scoring system to predict viable viral shedding after COVID-19 infection

Research may lead to safer ways to care for patients impacted by blood clots

Patients with scleroderma have reduced levels of Cathepsin L

Exploring remdesivir resistance in COVID-19-infected transplant recipients

UArizona researchers discover new protein that is responsible for controlling cell growth in yeasts

mRNA boosters associated with decreased odds of hospitalization compared with the mRNA vaccine primary series alone

High-tech lab in Nigeria could be a game changer in tackling emerging and re-emerging diseases

Transplantation tolerance associated with conventional T cells’ susceptibility to Treg suppression

Study offers support for increasing the use of living donor liver transplantation in Western countries

Study finds remdesivir-resistant version of COVID-19 in renal transplant recipients

Metal compounds could be the solution for drug-resistant fungal infections

Embedded bias: How medical records sow discrimination

The impact of sleep fragmentation on the clonal diversity of immune cells and the genetic aging of the hematopoietic system

Patient receives Pacific Northwest's first donation-after-circulatory-death heart transplant

Cleveland Clinic’s ROBIN center may pave way for more effective radiation, immunotherapy treatments

New board members bring significant leadership experience in the biotech sector

New modeling system identifies potential therapeutics for autosomal recessive polycystic kidney disease

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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