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Scientists discover new role for liver tPA in regulating cholesterol levels

Despite advances in treatment for high cholesterol, heart disease remains the leading cause of death in the U.S. Scientists at the Medical College of Wisconsin (MCW) are investigating the role of a form of cholesterol called very-low-density lipoprotein – and their findings may lead to new treatment options in the future.

1 Sep 2023

Michigan researchers receive $26 million NIH grant to study environmental impacts on child health

Backed by a $26 million federal grant, researchers at three Michigan universities, a leading health care system, and a state agency will continue a long-term study of how exposure to environmental factors during pregnancy and early childhood can impact health for a lifetime.

1 Sep 2023

SparkMaster 2: New software automates analysis of calcium release events

A team of UC Davis and University of Oxford researchers have developed an innovative tool: SparkMaster 2.

1 Sep 2023

Scientists reclassify 200 rare immune system disorders using network-based approach

Scientists at CeMM, Max Perutz Labs, and St. Anna Children's Cancer Research Institute in Vienna have achieved a significant advancement in the research of rare immune system disorders.

1 Sep 2023

Disparities in COVID-19 outcomes persist for American Indians/Alaska Natives

When the COVID-19 pandemic swept into New Mexico in the spring of 2020, seriously ill patients from all over the state were brought to The University of New Mexico Hospital in Albuquerque, where many wound up in intensive care, breathing with the help of ventilators.

1 Sep 2023

Black people still experience highest burden of air pollution-related deaths

Health benefits that have resulted from reductions in fine particulate air pollution aren't distributed equally among populations in the U.S., a new Yale-led study finds.

1 Sep 2023

Exposures to biological sources linked to increased risk of chemical intolerance

What initiates chemical intolerance (CI)? In a newly released survey of thousands of U.S. adults, respondents most frequently cited exposures to biological sources, such as mold and algae "blooms," and/or fossil fuels, their combustion products and synthetic chemical derivatives such as pesticides, plastics and persistent organic pollutants.

1 Sep 2023

New research could help improve the effectiveness of immunotherapy for people with brain tumors

A study led by researchers at the UCLA Jonsson Comprehensive Cancer Center sheds new light on why tumors that have spread to the brain from other parts of the body respond to immunotherapy while glioblastoma, an aggressive cancer that originates in the brain, does not.

1 Sep 2023

Integrating HIV and addiction treatment improves outcomes for people who inject drugs in Russia

New research from Boston Medical Center found that providing pragmatic support, specifically rapid access to antiretroviral therapy, pharmacotherapy for opioid use disorder, and strengths-based case management, improved treatment outcomes for people with HIV who inject drugs in St. Petersburg, Russia.

1 Sep 2023

CHEER receives $6M CDC grant to improve breastfeeding rates in Boston

The Center for Health Equity, Education, and Research (CHEER) at Boston Medical Center has received a $6,000,000 cooperative agreement from the Centers for Disease Control and Prevention (CDC).

1 Sep 2023

Combination of cediranib and lenalidomide does not improve outcomes in advanced thyroid cancer

Results of a multicenter phase II clinical trial led by the University of Chicago Medicine Comprehensive Cancer Center show that adding an immunomodulatory agent to treatment with the targeted tyrosine kinase inhibitor (TKI) cediranib did not make a difference in outcomes for treating patients with an advanced form of thyroid cancer that develops from thyroid follicular cells called differentiated thyroid cancer (DTC).

1 Sep 2023

Weighted lottery helps ensure equitable allocation of scarce COVID-19 medication

A program designed to ensure fairness and that people living in the most disadvantaged U.S. neighborhoods would be offered a scarce, potentially life-saving medication proved feasible in a large health system.

1 Sep 2023

Heart protective effect of red blood cells is enhanced by nitrate-rich vegetable diet

Red blood cells exposed to oxygen deficiency protect against myocardial infarction, according to a new KI study published in the Journal of Clinical Investigations.

1 Sep 2023

People in precarious employment more likely to die early, study says

People without a secure job contract can reduce their risk of premature death by 20 percent if they gain permanent employment, a study from Karolinska Institutet published in The Journal of Epidemiology and Community reports.

1 Sep 2023

Amgen presents late-breaking Phase 2 olpasiran data at ESC 2023

Amgen today announced data from the final analysis of the Phase 2 OCEAN(a)-DOSE study of olpasiran, a small interfering RNA (siRNA) during the Late-Breaking Science Session at the European Society of Cardiology (ESC) Annual Meeting being held in Amsterdam. In the off-treatment extension period, olpasiran showed a lasting effect on Lp(a) reduction nearly a year after the last dose.

From AMGEN 1 Sep 2023

When temps rise, so do medical risks. Should doctors and nurses talk more about heat?

An important email appeared in the inboxes of a small group of health care workers north of Boston as this summer started. It warned that local temperatures were rising into the 80s.

1 Sep 2023

TherageniX and University of Nottingham awarded £995K Innovate UK grant to develop powdered gene therapy for bone regeneration

Funding from Innovate UK’s Transforming Medicines Manufacturing program supporting innovative technologies for intracellular drug delivery.

1 Sep 2023

Can the consumption of colorful fruits and vegetables improve the management of gestational diabetes?

A new paper explores the dietary effects of consuming colorful fruits and vegetables (CFV).

1 Sep 2023

Low-dose aspirin linked to 15% lower risk of type 2 diabetes in older adults

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Hamburg, Germany (2-6 October) shows that use of low dose (100mg daily) aspirin among older adults aged 65 years and older is associated with a 15% lower risk of developing type 2 diabetes.

31 Aug 2023

Study shows strong link between depression and inflammation in obese patients before and after bariatric surgery

Research funded by the National Institute for Health and Care Research (NIHR) has shown that higher levels of inflammation in the blood of patients with obesity undergoing bariatric surgery predicts poorer weight loss six months after the procedure.

31 Aug 2023

Medicine News and Research

Scientists discover new role for liver tPA in regulating cholesterol levels

Michigan researchers receive $26 million NIH grant to study environmental impacts on child health

SparkMaster 2: New software automates analysis of calcium release events

Scientists reclassify 200 rare immune system disorders using network-based approach

Disparities in COVID-19 outcomes persist for American Indians/Alaska Natives

Black people still experience highest burden of air pollution-related deaths

Exposures to biological sources linked to increased risk of chemical intolerance

New research could help improve the effectiveness of immunotherapy for people with brain tumors

Integrating HIV and addiction treatment improves outcomes for people who inject drugs in Russia

CHEER receives $6M CDC grant to improve breastfeeding rates in Boston

Combination of cediranib and lenalidomide does not improve outcomes in advanced thyroid cancer

Weighted lottery helps ensure equitable allocation of scarce COVID-19 medication

Heart protective effect of red blood cells is enhanced by nitrate-rich vegetable diet

People in precarious employment more likely to die early, study says

Amgen presents late-breaking Phase 2 olpasiran data at ESC 2023

When temps rise, so do medical risks. Should doctors and nurses talk more about heat?

TherageniX and University of Nottingham awarded £995K Innovate UK grant to develop powdered gene therapy for bone regeneration

Can the consumption of colorful fruits and vegetables improve the management of gestational diabetes?

Low-dose aspirin linked to 15% lower risk of type 2 diabetes in older adults

Study shows strong link between depression and inflammation in obese patients before and after bariatric surgery

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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