Immune System News and Research

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Researchers launch randomized, placebo-controlled clinical trial of pulmozyme in COVID-19 patients

Researchers at Boston Children's Hospital and Brigham and Women's Hospital have launched a randomized, placebo-controlled clinical trial of dornase alfa (Pulmozyme) in patients with severe COVID-19 pneumonia and respiratory failure requiring mechanical ventilation.

29 Jul 2020

Study shows moderate exercise reduces side effects of prostate cancer treatment

New research published this weekinExperimental Physiologyfound that in prostate cancer survivors,a moderate bout of exercise kept the cell count of certain type of immune cells at a normal level, suggesting the exercise is safe for prostate cancer survivors.

29 Jul 2020

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

Analyses of lung fluid cells from COVID-19 patients conducted on the nation's fastest supercomputer point to gene expression patterns that may explain the runaway symptoms produced by the body's response to SARS-CoV-2.

28 Jul 2020

Researchers unlock new insights that may help inform vaccine design for infectious diseases

Vaccination is the most effective public health measure to prevent infectious diseases. Vaccines can greatly reduce the risk of infection by working with the body's natural defenses to safely develop immunity to disease.

28 Jul 2020

Study identifies phosphorylation-based biomarkers to guide cancer therapy

Precision medicine in cancer treatment uses genetic changes in the cancer cells to select the best therapies for individual patients.

28 Jul 2020

Protein produced by the human immune system can strongly inhibit Sars-Cov-2

A protein produced by the human immune system can strongly inhibit corona viruses, including Sars-Cov-2, the pathogen causing Covid-19. An international team from Germany, Switzerland and the USA successfully showed that the LY6E-Protein prevents coronaviruses from causing an infection.

28 Jul 2020

Human genome may explain the neonatal origins of chronic immune and inflammatory diseases

A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis and coeliac disease.

28 Jul 2020

Varying immune system responses can predict severe COVID-19 outcomes

The differing immune system responses of patients with COVID-19 can help predict who will experience moderate and severe consequences of disease, according to a new study by Yale researchers published July 27 in the journal Nature.

27 Jul 2020

Low plasma vitamin D level appears to be an independent risk factor for COVID-19 infection

Vitamin D is recognized as an important co-factor in several physiological processes linked with bone and calcium metabolism, and also in diverse non-skeletal outcomes, including autoimmune diseases, cardiovascular diseases, type 2 diabetes, obesity and cognitive decline, and infections.

27 Jul 2020

New strategy may help guard beta cells, slow the onset of type 1 diabetes

Type 1 diabetes occurs when a person's own immune system destroys insulin-producing beta cells in the pancreas. In recent years, scientists have learned how to grow large volumes of replacement beta cells, but the researchers are still trying out many options to protect these cells against the immune attack.

27 Jul 2020

Employers require COVID liability waivers as conflict mounts over workplace safety

After spending a May day preparing her classroom to reopen for preschoolers, Ana Aguilar was informed that the tots would not have to wear face masks when they came back. What's more, she had to sign a form agreeing not to sue the school if she caught COVID-19 or suffered any injury from it while working there.

27 Jul 2020

National clinical trial to test potential vaccine against SARS-CoV-2

UC San Diego Health and the Altman Clinical and Translational Research Institute, part of UC San Diego School of Medicine, will be sites for an accelerated national clinical trial to assess the efficacy and immunogenicity of a vaccine intended to protect against SARS-CoV-2, the novel coronavirus that causes COVID-19.

25 Jul 2020

Researchers identify TLR7 gene that predisposes elderly patients to severe COVID-19

Current observations suggest that the coronavirus SARS-CoV-2 causes severe symptoms mainly in elderly patients with chronic disease.

25 Jul 2020

MP Biomedicals and A*STAR jointly develop rapid antibody test kit for COVID-19

MP Biomedicals Asia Pacific Pte Ltd, a diagnostic corporation which has been operating for over 30 years focusing on various infectious disease testing development and manufacturing, today announced the successful development of a rapid antibody test kit for COVID-19, in collaboration with the Agency for Science, Technology and Research.

From MP Biomedicals, LLC 25 Jul 2020

Spinal cord injuries in mice cause acquired bone marrow failure syndrome

Research conducted at The Ohio State University Wexner Medical Center and The Ohio State University College of Medicine found that spinal cord injuries in mice cause an acquired bone marrow failure syndrome that may contribute to chronic immune dysfunction.

24 Jul 2020

Study shows how protective T cells become pathogenic in atherosclerosis

High cholesterol kills. In fact, one in four Americans will die from the consequences of atherosclerosis, the buildup of plaques of fat and cholesterol in the arteries. Statins have helped reduce mortality, but millions are still at risk.

24 Jul 2020

Scientists discover how coronavirus enters cells without encountering immune system resistance

With an alarm code, we can enter a building without bells going off. It turns out that the SARS coronavirus 2 (SARS-CoV-2) has the same advantage entering cells. It possesses the code to waltz right in.

24 Jul 2020

Researchers design new version of protein to develop COVID-19 vaccine

Responding to a need to quickly develop billions of doses of lifesaving COVID-19 vaccines, a scientific team at The University of Texas at Austin has successfully redesigned a key protein from the coronavirus, and the modification could enable much faster and more stable production of vaccines worldwide.

24 Jul 2020

Modulating immunometabolic processes to control lung infection

When drugs to kill microbes are ineffective, host-directed therapy uses the body's own immune system to deal with the infection.

23 Jul 2020

Combining two immunotherapies into a single treatment found to be more effective

Some of the most promising advances in cancer treatment have centered on immunotherapies that rev up a patient's immune system to attack cancer. But immunotherapies don't work in all patients, and researchers have been searching for ways to increase their effectiveness.

23 Jul 2020

Immune System News and Research

Researchers launch randomized, placebo-controlled clinical trial of pulmozyme in COVID-19 patients

Study shows moderate exercise reduces side effects of prostate cancer treatment

Computational analyses suggest new pathway for inflammatory response to SARS-CoV-2

Researchers unlock new insights that may help inform vaccine design for infectious diseases

Study identifies phosphorylation-based biomarkers to guide cancer therapy

Protein produced by the human immune system can strongly inhibit Sars-Cov-2

Human genome may explain the neonatal origins of chronic immune and inflammatory diseases

Varying immune system responses can predict severe COVID-19 outcomes

Low plasma vitamin D level appears to be an independent risk factor for COVID-19 infection

New strategy may help guard beta cells, slow the onset of type 1 diabetes

Employers require COVID liability waivers as conflict mounts over workplace safety

National clinical trial to test potential vaccine against SARS-CoV-2

Researchers identify TLR7 gene that predisposes elderly patients to severe COVID-19

MP Biomedicals and A*STAR jointly develop rapid antibody test kit for COVID-19

Spinal cord injuries in mice cause acquired bone marrow failure syndrome

Study shows how protective T cells become pathogenic in atherosclerosis

Scientists discover how coronavirus enters cells without encountering immune system resistance

Researchers design new version of protein to develop COVID-19 vaccine

Modulating immunometabolic processes to control lung infection

Combining two immunotherapies into a single treatment found to be more effective

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