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Discovery could lead to more effective treatments for cancers

Case Western Reserve University biochemical researchers have identified a new function of a key protein that leads to cancer–a finding they believe could lead to more effective treatments for a range of cancers and other diseases.

31 Aug 2023

Unique openings in specific ion channels could lead to development of selective drugs

Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge.

31 Aug 2023

Scientists delve deeper into how vaccines work against leishmaniasis

Scientists have established the effectiveness of vaccines they developed to prevent the disfiguring skin disease leishmaniasis in animal studies, and Phase 1 human trial planning is in motion for the most promising candidate.

31 Aug 2023

Socioeconomic distress linked to worse outcomes after heart transplantation

People from socioeconomically distressed communities who underwent heart transplantation between 2004 and 2018 faced a 10% greater relative risk of experiencing graft failure and dying within five years compared to people from non-distressed communities.

31 Aug 2023

Study reveals pathogenic mechanism of rare pediatric neurodegenerative disorder

A recent study published in Nature Metabolism has revealed the pathogenic mechanism underlying a rare pediatric neurodegenerative disorder known as mitochondrial enoyl reductase protein-associated neurodegeneration (MEPAN) syndrome.

31 Aug 2023

Universal approach could potentially expand CAR T cell therapy to all blood cancers

A broad new strategy could hold hope for treating virtually all blood cancers with CAR T cell therapy, which is currently approved for five subtypes of blood cancer.

31 Aug 2023

ER-phagy alleviates drug-induced cardiomyopathy in cancer patients

A cell contains many specialized subunits, called organelles, that carry out important tasks such as energy generation, protein synthesis, and calcium outflux. But what happens when something goes wrong with one of the organelles?

31 Aug 2023

Exploring the role of the metabolic syndrome in individual mechanisms of liver fibrosis

Chronic liver injury results in the development of liver fibrosis in approximately 25% of individuals in response to diverse insults, and several aspects of the development of liver injury appear to be common to a variety of initiating factors.

31 Aug 2023

KFF Health News' 'What The Health?': 3 health policy experts you should know

In this special episode, host Julie Rovner, KFF Health News' chief Washington correspondent, interviews three noted health policy experts.

31 Aug 2023

Largest genetic study of epilepsy finds new risk genes

The largest genetic study of its kind, coordinated by the International League Against Epilepsy, including scientists from FutureNeuro at RCSI University of Medicine and Health Sciences, has discovered specific changes in our DNA that increase the risk of developing epilepsy.

31 Aug 2023

Antioxidants stimulate the formation of new blood vessels in lung cancer tumors

Vitamin C and other antioxidants stimulate the formation of new blood vessels in lung cancer tumors, a new study from Karolinska Institutet published in The Journal of Clinical Investigation shows.

31 Aug 2023

Scientists discover new microglial population important for memory and learning

Following more than seven years of research, researchers at the University of Seville-IBiS (Institute of Biomedicine of Seville) have identified a new key cell type with a critical role in the developmental processes of memory and learning.

31 Aug 2023

Study finds semaglutide provides benefits for patients with obesity phenotype of heart failure and HFpEF

Researchers evaluated the efficacy of semaglutide in patients with the obesity phenotype of heart failure and preserved ejection fraction.

31 Aug 2023

Higher-income individuals at increased risk of melanoma in Atlantic Canada, study finds

A new study led by McGill University examines why people living in Atlantic regions are more at-risk for developing melanoma than other Canadians, providing lessons on skin cancer prevention for the whole country.

31 Aug 2023

Study suggests sepsis as a considerable burden to public health

A research team at Lund University in Sweden has found that more than four percent of all hospital admissions in southern Sweden are associated with sepsis.

31 Aug 2023

Exercise can also have a major impact on mental health

Exercising can be absolutely awful. However, none of our excuses matter when it comes to the health benefits. The benefits go beyond physical health —exercise also has a major impact on mental health.

31 Aug 2023

All five of Henry Ford Health's acute care hospitals earn NAPBC accreditation

All five of Henry Ford Health's acute care hospitals have earned a full three-year reaccreditation by the National Accreditation Program for Breast Centers (NAPBC), a quality program administered by the American College of Surgeons. With Henry Ford Hospital Detroit, Henry Ford Jackson Hospital, Henry Ford Macomb Hospital, Henry Ford West Bloomfield Hospital and Henry Ford Wyandotte Hospital earning full reaccreditation, Henry Ford has the highest number of Commission on Cancer and NAPBC-accredited hospitals of any health system in Michigan.

31 Aug 2023