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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Four years after shelter-in-place, covid-19 misinformation persists

From spring break parties to Mardi Gras, many people remember the last major “normal” thing they did before the novel coronavirus pandemic dawned, forcing governments worldwide to issue stay-at-home advisories and shutdowns.

1 Apr 2024

DNA repair process key to memory formation, study finds

Study reveals that learning triggers a series of molecular events including DNA damage and repair in hippocampal neurons, mediated by TLR9, crucial for memory formation.

31 Mar 2024

Researchers decode the evolutionary pathway of regulatory proteins

New research from the University of Wisconsin–Madison decodes the evolutionary pathway of regulatory proteins, the molecules that help control gene expression.

29 Mar 2024

Rapid miRNA detection with one-pot isothermal rolling circle amplification

This study is led by Professor Jue Ruan (Chinese Academy of Agricultural Sciences, Shenzhen, China). The authors developed a one-pot isothermal detection method based on rolling circle amplification (RCA) for rapid and specific detection of miRNAs and short RNA fragments.

29 Mar 2024

Sweeteners do not increase hunger and help lower blood sugar, study finds

Replacing sugar with artificial and natural sweeteners in foods does not make people hungrier – and also helps to reduce blood sugar levels, a significant new study has found.

28 Mar 2024

New DNA nanomachine targets breast cancer with precision

Breast cancer is the most common malignancy in women, posing a serious threat to the female health. Due to the high inter- and intra-tumoral heterogeneity of breast cancer, clinical treatment and prognosis can vary greatly in patients.

28 Mar 2024

Predicting treatment response in common blood cancer with DNA methylation profiling

A recent study led by Dr. Manel Esteller, Director of the Josep Carreras Institute, shows how DNA methylation profiling in a common type of blood cancer, myelodysplastic syndrome, predicts whether the patient will respond to treatment.

28 Mar 2024

Genetic test streamlines diagnosis of rare developmental disorders

A single genetic test could potentially replace the current two-step approach to diagnosing rare developmental disorders in children. This shift could enable earlier diagnoses for families and save the NHS vital resources.

28 Mar 2024

Using microbiota analysis for health and disease management

The human body harbors approximately 30 trillion microbes, known collectively as the microbiota.

28 Mar 2024

Dartmouth research unlocks extended cell death pathway in aging brain cells

For oligodendrocytes-;the central nervous system cells critical for brain function-;age may not bring wisdom, but it does come with the power to cling to life for much, much longer than scientists knew.

28 Mar 2024

Breakthrough tool illuminates neural stem cell dynamics

Researchers can use the light naturally thrown off by biological specimens to better study the different states of stem cells in the nervous system, thanks to a tool developed at the University of Wisconsin–Madison, brightening their chances for studying the way stem cells age.

27 Mar 2024

DNA damage in neurons crucial for creating stable memories

Just as you can't make an omelet without breaking eggs, scientists at Albert Einstein College of Medicine have found that you can't make long-term memories without DNA damage and brain inflammation. Their surprising findings were published online today in the journal Nature.

27 Mar 2024

Study sheds light on the interplay of genes in smoking addiction

Take a puff of nicotine for the first time, and your DNA plays an important role, alongside social and environmental factors, in shaping what happens next.

26 Mar 2024

New genetic system analyzes the underlying mechanisms of CRISPR-based DNA repair outcomes

Since its breakthrough development more than a decade ago, CRISPR has revolutionized DNA editing across a broad range of fields.

26 Mar 2024

ABT199/venetoclax synergism with thiotepa enhances cytotoxicity of chemo drugs in AML cells

A new research paper was published in Oncotarget's Volume 15 on March 14, 2024, entitled, "ABT199/venetoclax synergism with thiotepa enhances the cytotoxicity of fludarabine, cladribine and busulfan in AML cells."

26 Mar 2024

Key Charpentier/Doudna CRISPR patent upheld by China National Intellectual Property Administration

RS Genomics Limited, which was formed to provide broad access to the foundational CRISPR/Cas9 intellectual property co-owned by Dr. Emmanuelle Charpentier, today announced its patent CN201380038920.6 was upheld by the CNIPA in response to an invalidation challenge.

From ERS Genomics 26 Mar 2024