Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Scientists receive prestigious grant to explore the effects of prior knowledge on learning and memory

The Canadian Institute of Health Research (CIHR) has awarded a team of scientists at Baycrest's Rotman Research Institute (RRI) a prestigious grant to determine why having prior knowledge on a topic affects how we learn new, related information as we age.

27 Apr 2021

Researchers assess the theoretical impact of biomarker framework on dementia prediction

One of the biggest challenges in Alzheimer's research is to identify biomarkers that can identify people who are at risk of developing dementia. Biomarkers could be used to screen people so they might be helped before they develop dementia.

26 Apr 2021

UTHSC researchers receive $1.99 million to advance understanding of diabetes pathophysiology

The National Institute of Diabetes and Digestive and Kidney Diseases recently awarded a team of UTHSC researchers $1.99 million for their work to advance understanding of the pathophysiology of prediabetes, diabetes, and related complications.

22 Apr 2021

Researchers identify the cause of severe canine juvenile epilepsy

In a study conducted at the University of Helsinki, researchers found a cause for severe epilepsy resulting in death in Parson Russell Terrier puppies at a few months of age. A change in the PITRM1 gene can lead to a dysfunction of mitochondria, the cellular energy pumps.

21 Apr 2021

Chaperone protein imbalance can play key role in initiating toxic tau buildup in the aging brain

Chaperone protein imbalance can play a significant role in initiating toxic accumulation of tau in the aging brain - an early step in the development of Alzheimer's disease and related neurodegenerative disorders known as tauopathies, a new preclinical study by University of South Florida Health (USF Health) neuroscientists suggests.

20 Apr 2021

SARS-CoV-2 nucleoprotein can trigger α-synuclein amyloid fibril formation

A new study, released as a preprint on the bioRxiv* server, casts some light on the pathogenesis of acute and subacute neurological complications associated with COVID-19.

19 Apr 2021

Study sheds light on how tau aggregates promote Alzheimer’s disease

Look deep inside the brain of someone with Alzheimer's disease, most forms of dementia or the concussion-related syndrome known as chronic traumatic encephalopathy (CTE) and you'll find a common suspected culprit: stringy, hairball-like tangles of a protein called tau.

17 Apr 2021

Engaging in household chores may be beneficial for brain health in older adults

Engaging in household chores may be beneficial for brain health in older adults. In a recent Baycrest study, older adults who spent more time on household chores showed greater brain size, which is a strong predictor of cognitive health.

16 Apr 2021

Targeting brain protein may lead to new therapeutic approaches for neurodegenerative disorders

Neurological disorders are the number one cause of disability in the world, leading to seven million deaths each year. Yet few treatments exist for these diseases, which progressively diminish a person's ability to move and think.

16 Apr 2021

Researchers discover a new way to prevent brain nerve cells from deteriorating after injury

Violent blows or jolts to the head can cause traumatic brain injury (TBI), and there are currently about five million people in the U.S. living with some form of chronic impairment after suffering a TBI.

13 Apr 2021

Research on mysterious gene may lead to new treatments for Parkinson’s disease

More than 20 years after the discovery of the parkin gene linked to young-onset Parkinson's disease, researchers at The Ottawa Hospital and the University of Ottawa may have finally figured out how this mysterious gene protects the brain.

8 Apr 2021

HSV-1 infection induces strain-specific transcriptional differences in infected neurons

Why do some people with cold sores around their lips experience painful lesions, while others have no symptoms at all, yet still spread the virus? A new study conducted at Penn State finds that these differences could be due to variations in the way certain strains of herpes simplex (HSV-1) -- the virus that causes cold sores, as well as genital herpes -- activate gene expression in neurons.

29 Mar 2021

Major CIHR grant to help find and tackle the root cause of neurodegenerative disease

Dr. Simonetta Sipione, GlycoNet Investigator and Professor in the Department of Pharmacology at the University of Alberta, was recently awarded a major five-year grant from the Canadian Institutes of Health Research, worth $1.04 million.

26 Mar 2021

Sargramostim drug can also improve memory in people with mild-to-moderate Alzheimer's disease

A new study suggests that Sargramostim, a medication often used to boost white blood cells after cancer treatments, is also effective in treating and improving memory in people with mild-to-moderate Alzheimer's disease.

24 Mar 2021

New high-throughput system for testing drug candidates to treat brain diseases

On the basis of a license agreement with the German Center for Neurodegenerative Diseases (DZNE) and the Leibniz Institute of Polymer Research Dresden (IPF), the Dresden-based start-up "Neuron-D GmbH" is developing a high-throughput system for testing drug candidates to treat neurodegenerative diseases.

18 Mar 2021

Neurodegeneration News and Research

Further Reading

Scientists receive prestigious grant to explore the effects of prior knowledge on learning and memory

Researchers assess the theoretical impact of biomarker framework on dementia prediction

UTHSC researchers receive $1.99 million to advance understanding of diabetes pathophysiology

Researchers identify the cause of severe canine juvenile epilepsy

Chaperone protein imbalance can play key role in initiating toxic tau buildup in the aging brain

SARS-CoV-2 nucleoprotein can trigger α-synuclein amyloid fibril formation

Study sheds light on how tau aggregates promote Alzheimer’s disease

Engaging in household chores may be beneficial for brain health in older adults

Targeting brain protein may lead to new therapeutic approaches for neurodegenerative disorders

Researchers discover a new way to prevent brain nerve cells from deteriorating after injury

Research on mysterious gene may lead to new treatments for Parkinson’s disease

HSV-1 infection induces strain-specific transcriptional differences in infected neurons

Major CIHR grant to help find and tackle the root cause of neurodegenerative disease

Sargramostim drug can also improve memory in people with mild-to-moderate Alzheimer's disease

New high-throughput system for testing drug candidates to treat brain diseases

Inhibition of complement disrupts neurodegeneration, improves cognitive function in TBI patients

Study: Type 2 diabetes can increase risk of Parkinson's disease

New research project to explore the impact of urban lighting on health and wellbeing

UTHSC researchers awarded $1.9 million to study white matter mechanisms underlying dementia

Study demonstrates intricate relationship between Prpf19 and Exoc7 in inherited ataxias

eBook: Hallmarks of Neurodegeneration eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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