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Study finds geographical differences in PCOS symptoms among black and white women

Women with polycystic ovary syndrome (PCOS) in Alabama may be more likely to have excessive hair growth and insulin resistance, whereas women with PCOS in California may be more likely to have higher testosterone levels, according to new research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

11 Oct 2022

CMU Array holds potential to transform how doctors treat neurological disorders

Carnegie Mellon University researchers have pioneered the CMU Array-;a new type of microelectrode array for brain computer interface platforms.

5 Oct 2022

New project secures NIH funding to tackle chronic health disparities

Chronic diseases such as diabetes, heart disease and cancer disproportionally affect racial and ethnic minorities.

5 Oct 2022

Decline in specific protein levels linked to Alzheimer’s disease, not buildup of amyloid plaques

New research from the University of Cincinnati bolsters a hypothesis that Alzheimer's disease is caused by a decline in levels of a specific protein, contrary to a prevailing theory that has been recently called into question.

5 Oct 2022

Breath tests can lead to more personalized therapies for IBS patients

A new study led by Cedars-Sinai investigators found using breath tests to identify gut gas profiles can potentially help lead to more personalized therapies for people diagnosed with irritable bowel syndrome (IBS).

30 Sep 2022

uPAR may be a promising target for therapy in patients with neuroendocrine neoplasms

A novel PET radiotracer can accurately assess the presence of a biomarker that indicates the level of tumor aggressiveness in neuroendocrine neoplasms (NENs).

28 Sep 2022

New lab technique could spark a 'paradigm shift' in testing protein-based drugs

New Jersey Institute of Technology researchers have unveiled a new lab technique they say represents a "paradigm shift" in how pharmaceutical laboratories test and produce new protein-based drugs, such as therapeutic monoclonal antibodies being developed to treat a variety of diseases, from cancers to infectious diseases.

27 Sep 2022

Leducq Foundation awards $15 million to advance the understanding of atherosclerosis

The Leducq Foundation has awarded $15 million to researchers at UVA Health and their collaborators to advance our understanding of atherosclerosis, or hardening of the arteries, and find better ways to treat it. Diseases linked to atherosclerosis are the leading cause of death in the United States.

27 Sep 2022

Designing a new treatment to treat migraine effectively

In this interview, we speak to Mudra Kapoor, Vice President of Global Medical Affairs for Neuroscience at AbbVie, about atogepant, their new treatment option for migraine.

From AbbVie 26 Sep 2022

Genome editing approaches enable precise gene correction and disease rescue in inherited retinal diseases

In a new paper, University of California, Irvine researchers explain how precision genome editing agents have enabled precise gene correction and disease rescue in inherited retinal diseases (IRDs).

23 Sep 2022

Human gene variant in ADHD, autism exposes sex-dependence of neuronal signaling mechanisms

The prevalence, age of onset, and clinical symptoms for virtually all neuropsychiatric disorders differ between men and women. Among the disorders with pronounced sex bias are Attention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD), where the ratio of males/females diagnosed is approximately 4 to 1.

21 Sep 2022

Large clinical trial compares four drugs commonly used to treat type 2 diabetes

In a large clinical trial that directly compared four drugs commonly used to treat type 2 diabetes, researchers found that insulin glargine and liraglutide performed the best of four medications approved by the U.S. Food and Drug Administration to maintain blood glucose levels in the recommended range.

21 Sep 2022

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

A mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer's disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment, according to a new USC study.

21 Sep 2022

UC San Diego team receives $1.2 million to create a novel system to study chronic low back pain

A multidisciplinary team led by researchers at UC San Diego has received $1.2 million from the National Science Foundation to create a novel system to study and inform the treatment of chronic low back pain.

20 Sep 2022

Study shows differences in treatment outcomes for Black vs. white women with hormone receptor-positive breast cancer

A study led by City of Hope, one of the largest cancer research and treatment organizations in the United States, found that Black women with Stage 1 or 2 breast cancer were almost three times more likely than white women to have tumor shrinkage from hormone therapy delivered prior to surgery, yet Black women were more likely than their white counterparts to have worse outcomes when this type of endocrine therapy before surgery was used at a later stage of disease.

16 Sep 2022

STRATAGEM aims to provide new perspectives on multidrug-resistant solid tumors

Achieving a good efficacy of chemotherapy is one of the major challenges still unresolved in oncological patients. The main limitation to the efficacy of chemotherapy is the multidrug-resistant (MDR) phenotype, a multiple cross-resistance towards different anticancer drugs.

14 Sep 2022

Scientists identify two distinct subtypes of obesity

A team led by Van Andel Institute scientists has identified two distinct types of obesity with physiological and molecular differences that may have lifelong consequences for health, disease and response to medication.

14 Sep 2022

New drug marks cancer cells for destruction by the immune system

Tumor cells are notoriously good at evading the human immune system; they put up physical walls, wear disguises and handcuff the immune system with molecular tricks.

13 Sep 2022

UC San Diego selected to lead components of the NIH Common Fund's Bridge2AI program

Researchers at University of California San Diego School of Medicine have been selected to lead components of the National Institutes of Health (NIH) Common Fund's Bridge to Artificial Intelligence (Bridge2AI) program.

13 Sep 2022

Study investigates the efficacy and safety of selpercatinib in a diverse group of patients

The highly selective RET inhibitor selpercatinib was well-tolerated and achieved durable objective responses across multiple tumor types in the Phase I/II LIBRETTO-001 trial, according to researchers from The University of Texas MD Anderson Cancer Center.

13 Sep 2022

Precision Medicine News and Research

Study finds geographical differences in PCOS symptoms among black and white women

CMU Array holds potential to transform how doctors treat neurological disorders

New project secures NIH funding to tackle chronic health disparities

Decline in specific protein levels linked to Alzheimer’s disease, not buildup of amyloid plaques

Breath tests can lead to more personalized therapies for IBS patients

uPAR may be a promising target for therapy in patients with neuroendocrine neoplasms

New lab technique could spark a 'paradigm shift' in testing protein-based drugs

Leducq Foundation awards $15 million to advance the understanding of atherosclerosis

Designing a new treatment to treat migraine effectively

Genome editing approaches enable precise gene correction and disease rescue in inherited retinal diseases

Human gene variant in ADHD, autism exposes sex-dependence of neuronal signaling mechanisms

Large clinical trial compares four drugs commonly used to treat type 2 diabetes

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

UC San Diego team receives $1.2 million to create a novel system to study chronic low back pain

Study shows differences in treatment outcomes for Black vs. white women with hormone receptor-positive breast cancer

STRATAGEM aims to provide new perspectives on multidrug-resistant solid tumors

Scientists identify two distinct subtypes of obesity

New drug marks cancer cells for destruction by the immune system

UC San Diego selected to lead components of the NIH Common Fund's Bridge2AI program

Study investigates the efficacy and safety of selpercatinib in a diverse group of patients

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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