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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Researchers discover previously unknown anti-phage defense mechanism in certain bacteria

Researchers from Singapore-MIT Alliance for Research and Technology, MIT’s research enterprise in Singapore, have discovered a new anti-phage defense mechanism found in some bacteria, which uses previously unknown features to protect their DNA.

7 May 2020

Research looks at best ways to disinfect N95 masks for reuse

The world is gripped by the COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The health care personnel and those caring for these patients are at considerable risk of contracting the infection. N95 masks have been mentioned as protective face gear to cover the face, nose, and mouth of the user to prevent the spread of the infection via aerosols generated while coughing, sneezing, or even breathing.

6 May 2020

New anti-phage defense mechanism in bacteria protects their DNA, finds study

Researchers from Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, have discovered a new anti-phage defense mechanism found in some bacteria, which uses previously unknown features to protect their DNA.

6 May 2020

Study finds race-specific lupus nephritis biomarkers for early diagnosis, treatment

University of Houston Hugh Roy and Lillie Cranz Cullen Endowed Professor of biomedical engineering, Chandra Mohan, and his team have discovered a difference in urinary biomarker proteins of lupus nephritis in patients according to race.

6 May 2020

Interleukin-12 electroporation led to clinical responses in patients with advanced melanoma

Combining intratumoral electroporation of interleukin-12 (IL-12) DNA (tavokinogene telseplasmid, or TAVO) with the immune checkpoint inhibitor pembrolizumab (Keytruda) led to clinical responses in patients with immunologically quiescent advanced melanoma, according to results from a phase II trial.

6 May 2020

OXGENE™ reports third consecutive year of 100% year on year revenue growth

OXGENE™ has more than doubled its annual revenue in the financial year just closed, in the third consecutive year of 100% year on year revenue growth.

From OXGENE 6 May 2020

Study: Genetics of AQP4 water channels impact the intensity of deep sleep

The reason why we sleep remains an unresolved question of the 21st century. Research by Sara Marie Ulv Larsen, Sebastian Camillo Holst and colleagues from the Neurobiology Research Unit at the University Hospital Copenhagen, published this week in the open access journal PLoS Biology, now shows that the depth of non-rapid-eye-movement (nonREM) sleep in humans is associated with different genetic versions of a gene that encodes a water channel involved in fluid flow in the brain.

6 May 2020

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

An international team led by Emory scientists has gained insight into the pathological mechanisms behind two devastating neurodegenerative diseases.

6 May 2020

New tool may offer a novel approach to prevent multiple chronic diseases

A study just released by Columbia University Mailman School of Public Health is reporting a blood-DNA-methylation measure that is sensitive to variation in the pace of biological aging among individuals born the same year.

6 May 2020

Study provides more insight into the initiation and progression of human cancers

Volume 11, Issue 18 of @Oncotarget Clinical implications of chromatin accessibility assessed by ATAC-seq profiling in human cancers especially in a large patient cohort is largely unknown.

6 May 2020

Researchers discover new gene involved in regulating the body's cholesterol

Precision medicine has the potential to tailor treatments to a patient's unique genetic sequence. But achieving this precision -- or developing new drugs -- requires knowing which genes are involved in disease.

4 May 2020

Wyss Institute and Cytosurge collaborate to improve CRISPR multiplexing

Today, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Cytosurge AG, a company manufacturing unique high-precision nanotechnology instruments, announced that they will collaboratively investigate CRISPR-based approaches to more effectively introduce multiple edits into the genome of single cells, while minimizing CRISPR-related toxicity.

4 May 2020

Scientists develop CRISPR-based test for SARS-CoV-2

Now, a team of scientists at the University of California Santa Barbara has developed a low-cost, rapid, and high-tech test that can detect SARS-CoV-2 effectively. They have developed a CRISPR-based test that is sensitive and effective as traditional tests.

4 May 2020

Researchers discover neural circuit that drives physical responses to emotional stress

Researchers at Nagoya University have discovered a neural circuit that drives physical responses to emotional stress.

4 May 2020

Scientists develop new way to deliver molecules that target specific genes within cells

A group of researchers from University of Toronto Engineering and SickKids Hospital have developed a new way to deliver molecules that target specific genes within cells.

4 May 2020

Individuals with high risk of cancer and CVD cannot be identified based on family history

Certain genetic changes, termed "pathogenic variants," substantially increase risk for cardiovascular disease and cancer--the leading causes of death--but testing to identify individual carriers is not part of current clinical practice.

4 May 2020

Scripps professor receives Research Program Award for advancing RNA-targeting medicines

In recognition of his high-impact work advancing the field of RNA-targeting medicines, the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health, has awarded Scripps Research Chemistry Professor Matthew Disney, PhD, a prestigious Research Program Award, to aid Disney's development of treatments for incurable diseases such as Alzheimer's, Parkinson's, ALS and frontotemporal dementia.

4 May 2020

DNA News and Research

Further Reading

Researchers discover previously unknown anti-phage defense mechanism in certain bacteria

Research looks at best ways to disinfect N95 masks for reuse

New anti-phage defense mechanism in bacteria protects their DNA, finds study

Study finds race-specific lupus nephritis biomarkers for early diagnosis, treatment

Interleukin-12 electroporation led to clinical responses in patients with advanced melanoma

OXGENE™ reports third consecutive year of 100% year on year revenue growth

Study: Genetics of AQP4 water channels impact the intensity of deep sleep

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

New tool may offer a novel approach to prevent multiple chronic diseases

Study provides more insight into the initiation and progression of human cancers

Researchers discover new gene involved in regulating the body's cholesterol

Wyss Institute and Cytosurge collaborate to improve CRISPR multiplexing

Scientists develop CRISPR-based test for SARS-CoV-2

Researchers discover neural circuit that drives physical responses to emotional stress

Scientists develop new way to deliver molecules that target specific genes within cells

Individuals with high risk of cancer and CVD cannot be identified based on family history

Scripps professor receives Research Program Award for advancing RNA-targeting medicines

Real-time monitoring of biochemical processes on DNA using infrared spectroscopy

Study reports cryo-EM structure of Remdesivir-bound RNA replicase complex from SARS-CoV-2

DNA damage and inaccurate repair mechanisms jointly cause mutational signatures

eBook: Exploring the Cell Cycle and DNA Damage and Repair eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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