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Vaccination reduces risk of severe COVID-19 in solid organ transplant recipients

Findings from a two-year study of nearly 2,400 solid organ transplant recipients, conducted by the Johns Hopkins Transplant Research Center (TRC) in collaboration with the New York University Center for Surgical and Applied Transplant Research, indicate spikes of post-vaccination SARS-CoV-2 viral infections (commonly known as COVID-19 breakthrough cases) remain common, yet hospitalization rates have dramatically dropped following the first wave of the virus' omicron subvariant.

18 Aug 2023

E-cigarette usage nudges people toward quitting smoking, study shows

E-cigarettes do have value as a smoking cessation aid, according to a new study just released by a team of MUSC Hollings Cancer Center researchers.

18 Aug 2023

Severe COVID-19 may cause long-term changes to innate immune system

Severe COVID-19 may cause long-lasting alterations to the innate immune system, the first line of defense against pathogens, according to a small study funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

18 Aug 2023

Tulane, Ochsner Health and RH Impact awarded $16.5 million grant to address Louisiana's high maternal mortality rate

Tulane University, Ochsner Health and the community nonprofit RH Impact have been awarded a seven-year, $16.5 million grant from the National Institutes of Health to establish a research center of excellence focused on finding solutions to address Louisiana's disproportionately high maternal mortality rate.

18 Aug 2023

Severe COVID-19 causes long-lasting changes to immune system stem cells

Severe COVID-19 infection triggers changes that affect gene expression in immune system stem cells, causing long-lasting alterations in the body's immune response, according to a new study by Weill Cornell Medicine and Jackson Laboratory investigators.

18 Aug 2023

Meta-analysis reports global prevalence of MAFLD of 38.8% in adults

Non-alcoholic fatty liver disease (NAFLD) is a common condition that affects up to 30% of adults in the general population.

18 Aug 2023

Japanese squirrels may be a model for human amyloidosis

A research group led by Dr. Tomoaki Murakami from the Tokyo University of Agriculture and Technology has revealed that fibrinogen Aα-chain amyloidosis, a previously unreported disease in animals other than humans, is highly prevalent in Japanese squirrels (Sciurus lis).

18 Aug 2023

Proxalutamide shows promise as potential COVID-19 treatment

At the outset of the COVID pandemic, men appeared to suffer higher rates of severe illness and death, leading researchers to suspect a link between androgen receptors-;which bind to hormones like testosterone--and SARS-CoV-2 viral infection.

18 Aug 2023

Dementia patients living alone at risk for medical problems, self-neglect

An estimated 1 in 4 older Americans with dementia or mild cognitive impairment lives alone and is at risk of practices like unsafe driving, wandering outside the home, mixing up medications and failing to attend medical appointments.

18 Aug 2023

Noelin1-3 proteins essential for learning and memory formation in the mammalian brain

A German-American research team headed by Prof. Dr. Bernd Fakler from the Faculty of Medicine at the University of Freiburg demonstrated the major influence of Noelin1-3 proteins on learning and memory formation in the mammalian brain.

18 Aug 2023

Medicaid expansion increases cancer clinical trial participation

The Medicaid expansion under the Patient Protection and Affordable Care Act resulted in a 19% annual increase in Medicaid-insured cancer patients participating in publicly funded clinical trials, according to researchers from Fred Hutchinson Cancer Center, the SWOG Statistics and Data Management Center and Columbia University.

18 Aug 2023

Gut microbiome may play a role in DNA methylation during weight loss

"Should I be taking a probiotic?" is a question that Maggie Stanislawski, PhD, assistant professor in the University of Colorado Department of Biomedical Informatics (DBMI), gets asked often.

18 Aug 2023

A new Medicare proposal would cover training for family caregivers

Even with extensive caregiving experience, Patti LaFleur was unprepared for the crisis that hit in April 2021, when her mother, Linda LaTurner, fell out of a chair and broke her hip.

18 Aug 2023

The association between diet pattern and depressive and anxiety symptoms

The associations between dietary patterns and depression or anxiety symptoms.

18 Aug 2023

Phase I trial shows promise: Brain stimulation spurs upper-extremity recovery in stroke patients

Researchers performed an open-label phase I trial.

18 Aug 2023

New findings could develop effective vaccines or treatments for chikungunya fever

Researchers at Albert Einstein College of Medicine have found that the virus responsible for chikungunya fever can spread directly from cell to cell-;perhaps solving the longstanding mystery of how the virus, now emerging as a major health threat, can manage to escape antibodies circulating in the bloodstream.

18 Aug 2023

Platelets quell the inflammation of an aging brain and body: Study finds

Platelets are behind the cognitive benefits of young blood, exercise and the longevity hormone klotho

18 Aug 2023

New method to assess the status of immune responses to specific antigens in detail

A new method to assess the status of immune responses to specific antigens in detail by analysis using the B cell receptor (BCR) repertoire has been developed by a research group, consisting of Assistant Professor Yohei Funakoshi, Associate Professor Kimikazu Yakushijin, Professor Hironobu Minami (Kobe University Graduate School of Medicine), Associate Professor Goh Ohji (Kobe University Hospital), and Researcher Takaji Matsutani (Repertoire Genesis Inc.).

18 Aug 2023

FDA approved Rexulti to be the first antipsychotic for treating agitation in elderly patients with dementia

In trials, the antipsychotic drug brexpiprazole (Rexulti) failed to provide a clinically meaningful benefit and increased the risk of death. Yet the US Food and Drug Administration (FDA) has fast tracked its approval, making Rexulti the first antipsychotic for treating agitation in elderly patients with dementia.

18 Aug 2023

New drug candidate nearly doubles survival for patients with aggressive childhood brain tumors

For the first time, researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain tumor for which there are no effective treatments.

17 Aug 2023

Medicine News and Research

Vaccination reduces risk of severe COVID-19 in solid organ transplant recipients

E-cigarette usage nudges people toward quitting smoking, study shows

Severe COVID-19 may cause long-term changes to innate immune system

Tulane, Ochsner Health and RH Impact awarded $16.5 million grant to address Louisiana's high maternal mortality rate

Severe COVID-19 causes long-lasting changes to immune system stem cells

Meta-analysis reports global prevalence of MAFLD of 38.8% in adults

Japanese squirrels may be a model for human amyloidosis

Proxalutamide shows promise as potential COVID-19 treatment

Dementia patients living alone at risk for medical problems, self-neglect

Noelin1-3 proteins essential for learning and memory formation in the mammalian brain

Medicaid expansion increases cancer clinical trial participation

Gut microbiome may play a role in DNA methylation during weight loss

A new Medicare proposal would cover training for family caregivers

The association between diet pattern and depressive and anxiety symptoms

Phase I trial shows promise: Brain stimulation spurs upper-extremity recovery in stroke patients

New findings could develop effective vaccines or treatments for chikungunya fever

Platelets quell the inflammation of an aging brain and body: Study finds

New method to assess the status of immune responses to specific antigens in detail

FDA approved Rexulti to be the first antipsychotic for treating agitation in elderly patients with dementia

New drug candidate nearly doubles survival for patients with aggressive childhood brain tumors

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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