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New artificial heart can adjust the changing needs of patients treated for end-stage heart failure

An experimental artificial heart includes an autoregulation control mechanism, or Auto-Mode, that can adjust to the changing needs of patients treated for end-stage heart failure.

21 Jun 2021

Study: Patients with two SARS-CoV-2 variants are less likely to be asymptomatic compared to control group

Although two SARS-CoV-2 variants are associated with higher transmission, patients with these variants show no evidence of higher viral loads in their upper respiratory tracts compared to the control group, a Johns Hopkins School of Medicine study found.

21 Jun 2021

New technique can measure metabolic process at the single-cell level

Understanding cellular metabolism - how a cell uses energy- could be key to treating a wide array of diseases, including vascular diseases and cancer.

18 Jun 2021

Blocking IL-11 signaling can promote liver regeneration after paracetamol-induced damage

Scientists at Duke-NUS Medical School and National Heart Centre Singapore, in collaboration with colleagues in Singapore and the UK, have shown that the human form of the signaling protein interleukin 11 (IL-11) has a damaging effect on human liver cells--overturning a prior hypothesis that it could help livers damaged by paracetamol poisoning.

18 Jun 2021

Deep learning could transform the ability to accurately interpret HIV test results

Pioneering technology developed by UCL and Africa Health Research Institute researchers could transform the ability to accurately interpret HIV test results, particularly in low- and middle-income countries.

18 Jun 2021

Novel vaccine based on mRNA technology protects against malaria in animal models

Scientists from the Walter Reed Army Institute of Research and Naval Medical Research Center partnered with researchers at the University of Pennsylvania and Acuitas Therapeutics to develop a novel vaccine based on mRNA technology that protects against malaria in animal models, publishing their findings in npj Vaccines.

18 Jun 2021

Could horse-derived antibody therapy be effective against SARS-CoV-2 variants of concern?

A new study, released as a preprint on the bioRxiv* server, reveals the high neutralizing efficacy of hyperimmune horse serum against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This could prove, if validated, to be a more affordable yet potent therapeutic in reducing the morbidity and mortality caused by this virus.

18 Jun 2021

First insights into human prion disease could help tackle neurodegenerative diseases

Surface features of human prions have been identified for the first time, which may provide key information into treatments of neurodegenerative diseases.

18 Jun 2021

Printable biosensor enables simultaneous recording and imaging of tissues, organs during surgery

Surgeons may soon be able to localize critical regions in tissues and organs during a surgical operation thanks to a new, patent-pending Purdue University biosensor that can be printed in 3D using an automated printing system.

18 Jun 2021

COVID-19 virus can infect the testes, hamster study shows

Researchers at the University of Texas Medical Branch have observed that SARS-CoV-2, the virus that causes COVID-19, can infect the testes of infected hamsters.

18 Jun 2021

New bio-inks for biosensors could make surgery safer

A research team from Los Alamos National Laboratory and Purdue University have developed bio-inks for biosensors that could help localize critical regions in tissues and organs during surgical operations.

18 Jun 2021

KIYATEC’s test results accurately predict treatment response in recurrent high-grade glioma patients

KIYATEC, Inc. announced today the publication of new peer-reviewed data that establishes clinically meaningful prediction of patient-specific responses to standard of care therapy, prior to treatment, in newly diagnosed glioblastoma (GBM) and other high-grade glioma (HGG) patients.

18 Jun 2021

New computational model simulates the spread and impact of COVID-19 virus

The emergence and rapid spread of novel Covid-19 coronavirus in early 2020 spurred numerous accelerated efforts to develop a vaccine. At the time it was not clear how effective these vaccines needed to be to slow or stop the pandemic.

18 Jun 2021

New platform can detect microRNA-205 with high sensitivity, excellent selectivity

In a paper published in NANO, a team of researchers from Jiangnan University, China have prepared a convenient sensing platform which can detect microRNA-205 (MiR-205) with high sensitivity and excellent selectivity using TpTta-COF nanosheet and fluorescent oligonucleotide probes.

18 Jun 2021

Study: Cancer cells grown in culture dishes have less parity with their human sources

In a bid to find or refine laboratory research models for cancer that better compare with what happens in living people, Johns Hopkins Medicine scientists report they have developed a new computer-based technique showing that human cancer cells grown in culture dishes are the least genetically similar to their human sources.

18 Jun 2021

Study finds new clues to explain how Alzheimer’s disease spreads in the brain

Case Western Reserve University researchers studying prions-;misfolded proteins that cause lethal incurable diseases-;have identified for the first time surface features of human prions responsible for their replication in the brain.

18 Jun 2021

Foresight Diagnostics to demonstrate utility of PhasED-Seq technology at ICML meeting

Foresight Diagnostics, the emerging leader in blood-based lymphoma disease monitoring, announced today that clinical performance of its minimal residual disease (MRD) detection platform in diffuse large B-cell lymphoma (DLBCL) will be presented at the 16th International Conference on Malignant Lymphoma (ICML) on June 18-22, 2021.

18 Jun 2021

Indian WHO study examines COVID-19 susceptibility in children versus adults

Now, a group of researchers from India have explored this concept due to the lack of solid evidence and have undertaken a community and population-based serosurveillance study for the coronavirus infection under the World Health Organisation (WHO) Unity umbrella. In this study, participants older than two years old were compared to older adults in terms of seropositivity.

17 Jun 2021

Novel drug class shows potential to treat cancer patients with faulty BRCA genes

Scientists have identified a new class of targeted cancer drugs that offer the potential to treat patients whose tumors have faulty copies of the BRCA cancer genes.

17 Jun 2021

Mouse-adapted SARS-CoV-2 and simian adenovirus vector advance COVID-19 vaccine research

A new preprint recently released on the bioRxiv* server describes the immunogenicity and protective potential of a novel adenovirus SARS-CoV-2 vaccine candidate against a form of the virus adapted to cause severe disease in mice. The findings show that this provides a useful mouse model for the study of new vaccines, in addition to demonstrating the protective efficacy of the current rhesus adenovirus vaccine candidate RhAd52.

17 Jun 2021

Laboratory News and Research

New artificial heart can adjust the changing needs of patients treated for end-stage heart failure

Study: Patients with two SARS-CoV-2 variants are less likely to be asymptomatic compared to control group

New technique can measure metabolic process at the single-cell level

Blocking IL-11 signaling can promote liver regeneration after paracetamol-induced damage

Deep learning could transform the ability to accurately interpret HIV test results

Novel vaccine based on mRNA technology protects against malaria in animal models

Could horse-derived antibody therapy be effective against SARS-CoV-2 variants of concern?

First insights into human prion disease could help tackle neurodegenerative diseases

Printable biosensor enables simultaneous recording and imaging of tissues, organs during surgery

COVID-19 virus can infect the testes, hamster study shows

New bio-inks for biosensors could make surgery safer

KIYATEC’s test results accurately predict treatment response in recurrent high-grade glioma patients

New computational model simulates the spread and impact of COVID-19 virus

New platform can detect microRNA-205 with high sensitivity, excellent selectivity

Study: Cancer cells grown in culture dishes have less parity with their human sources

Study finds new clues to explain how Alzheimer’s disease spreads in the brain

Foresight Diagnostics to demonstrate utility of PhasED-Seq technology at ICML meeting

Indian WHO study examines COVID-19 susceptibility in children versus adults

Novel drug class shows potential to treat cancer patients with faulty BRCA genes

Mouse-adapted SARS-CoV-2 and simian adenovirus vector advance COVID-19 vaccine research

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