Immune System News and Research

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Cone snail venom produces new type of insulin

Diabetes is a global health issue affecting millions. In 2014, there were 422 million diabetics, compared to 108 million in 1989. The condition can be treated with diet, physical activity, medicines like synthetic insulin injections, and regular screening.

3 Jun 2020

Rigidity of tissues drives immune system activity, UCLA study finds

A UCLA research team has identified a new paradigm for understanding the regulation of the immune system, potentially paving the way for new approaches to treating infections and immune-related diseases such as type 1 diabetes and certain cancers.

2 Jun 2020

Study reveals how a fat cell's immune response worsens obesity

When obesity occurs, a person's own fat cells can set off a complex inflammatory chain reaction that can further disrupt metabolism and weaken immune response--potentially placing people at higher risk of poor outcomes from a variety of diseases and infections, including COVID-19.

2 Jun 2020

Explosion of immune cells in mouse lungs after birth may help protect against infections

An explosion in the number and types of immune cells in the lungs of newborn mice likely helps them adapt to breathing and protects them from infection, says a new study published today in eLife.

2 Jun 2020

Study investigates outcome of COVID-19 infection in blood cancer patients

One of the first studies to investigate the outcome of COVID-19 infection in patients with blood cancer has been conducted by clinical researchers from Queen Mary University of London and Barts Health NHS Trust.

2 Jun 2020

CSL Behring and Seattle Children's partner to develop gene therapies for primary immunodeficiency diseases

Seattle Children's Research Institute, one of the top pediatric research institutions in the world, and global biotechnology leader CSL Behring announced a strategic alliance to develop stem cell gene therapies for primary immunodeficiency diseases.

2 Jun 2020

Fraunhofer researchers investigate the mechanisms of metastasis formation

What makes tumor cells turn murderous? The Fraunhofer Institute for Toxicology and Experimental Medicine ITEM is investigating the mechanisms of metastasis formation - and searching for approaches for new treatments in the fight against cancer.

2 Jun 2020

Researchers identify genetic codes of COVID-19 and SARS viruses that may promote their lifecycles

Researchers have identified specific portions of the genetic codes of the COVID-19 and SARS viruses that may promote the viruses' lifecycles. The new technique is researchers' first tool for determining what genetic sequences stored as RNA - DNA's chemical cousin - are more stable.

2 Jun 2020

Journal publication supports Synlogic’s first clinical immuno-oncology program, SYNB1891

Synlogic, Inc., a clinical-stage company applying synthetic biology to beneficial microbes to develop novel, living medicines, today announced the publication in Nature Communications of preclinical data supporting its first clinical immuno-oncology program, SYNB1891, which is being evaluated in Phase 1 clinical trial in patients with advanced solid tumors or lymphoma.

2 Jun 2020

Specific immune suppression leads to severe COVID-19 disease

A new study published online on the preprint server medRxiv in May 2020 reports that specific changes in the way the human immune system responds to COVID-19 determine whether the individual develops moderate or severe illness.

2 Jun 2020

Lancet issues correction on paper than prompted WHO to suspend Hydroxychloroquine trial

The World Health Organization (WHO) suspended the hydroxychloroquine trial amid the coronavirus pandemic. The decision comes after the study findings published in The Lancet reported issues on the drug's efficacy and safety. Now, the journal has issued a correction on the figures reported in the study.

2 Jun 2020

SARS-CoV-2 started spreading in the United States in January, CDC says

The United States has reported the highest number of infections across the globe, with more than 1.81 million confirmed cases and at least 105,000 deaths. The magnitude of the novel coronavirus spread hints that the virus may have started earlier than previously thought.

2 Jun 2020

Reducing inflammation improves stroke recovery, may extend window for therapy

Reperfusion therapy, the gold standard for stroke treatment, helps restore blood flow after a stroke caused by a clot, preventing loss of brain tissue. However, only about 10% of stroke patients qualify, in part because of reperfusion therapy's narrow treatment window.

1 Jun 2020

NAU scientist collaborating on vault-based vaccine to prevent and treat COVID-19

C. Todd French, assistant professor of biology and leader of Northern Arizona University's new COVID-19 Testing Service Center, is working with scientists at Vault Pharma, an emerging biotechnology company, to test candidate vaccines against the novel coronavirus.

1 Jun 2020

Study uncovers how cancer cells protect themselves from viruses

Researchers at the Francis Crick Institute have uncovered how cancer cells protect themselves from viruses that are harmful to tumors but not to healthy cells. These findings could lead to improved viral treatments for the disease.

1 Jun 2020

Study highlights potential benefits of new drug for inflammatory diseases

New research conducted by the University of Liverpool and AKL Research and Development Ltd, published in Inflammopharmacology, highlights the potential benefits of a new drug treatment on the human body's immune response in inflammation.

1 Jun 2020

Ruxolitinib shows promise in severe COVID-19

An anti-inflammatory drug Ruxolitinib has shown promising results in the treatment of severe coronavirus disease COVID-19. The study titled, “Ruxolitinib in treatment of severe coronavirus disease 2019 (COVID-19): A multicenter, single-blind, randomized controlled trial,” was published as a pre-proof for the Journal of Allergy and Clinical Immunology.

31 May 2020

New immunotherapy for metastatic non-small cell lung cancer shows promise in clinical trial

A new type of immunotherapy treatment for metastatic non-small cell lung cancer (NSCLC) is being tested by Missak Haigentz, Jr., MD, medical director of hematology and oncology for Atlantic Health System.

30 May 2020

Immunotherapy doubles progression-free survival time of patients with advanced bowel cancer

A large international trial involving UCL and University College London Hospitals NHS Foundation Trust (UCLH) has found that pembrolizumab, a form of immunotherapy, more than doubled the 'progression free survival' time of patients with a specific subtype of advanced bowel cancer, when compared with chemotherapy.

30 May 2020

Scientists identify factors influencing outcomes in kidney cancer patients treated with immunotherapy

By analyzing tumors from patients treated with immunotherapy for advanced kidney cancer in three clinical trials, Dana-Farber Cancer Institute scientists have identified several features of the tumors that influence their response to immune checkpoint inhibitor drugs.

30 May 2020

Immune System News and Research

Cone snail venom produces new type of insulin

Rigidity of tissues drives immune system activity, UCLA study finds

Study reveals how a fat cell's immune response worsens obesity

Explosion of immune cells in mouse lungs after birth may help protect against infections

Study investigates outcome of COVID-19 infection in blood cancer patients

CSL Behring and Seattle Children's partner to develop gene therapies for primary immunodeficiency diseases

Fraunhofer researchers investigate the mechanisms of metastasis formation

Researchers identify genetic codes of COVID-19 and SARS viruses that may promote their lifecycles

Journal publication supports Synlogic’s first clinical immuno-oncology program, SYNB1891

Specific immune suppression leads to severe COVID-19 disease

Lancet issues correction on paper than prompted WHO to suspend Hydroxychloroquine trial

SARS-CoV-2 started spreading in the United States in January, CDC says

Reducing inflammation improves stroke recovery, may extend window for therapy

NAU scientist collaborating on vault-based vaccine to prevent and treat COVID-19

Study uncovers how cancer cells protect themselves from viruses

Study highlights potential benefits of new drug for inflammatory diseases

Ruxolitinib shows promise in severe COVID-19

New immunotherapy for metastatic non-small cell lung cancer shows promise in clinical trial

Immunotherapy doubles progression-free survival time of patients with advanced bowel cancer

Scientists identify factors influencing outcomes in kidney cancer patients treated with immunotherapy

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