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Adaptimmune announces opening of pilot clinical trial in synovial sarcoma

Adaptimmune announced today that it has opened a Pilot, open-label clinical trial in synovial sarcoma at the National Cancer Institute (NCI), Bethesda, Maryland, testing its enhanced T cell receptor T cell therapy. A second site is planned to open later this year at Washington University, St. Louis, Missouri.

25 Jul 2011

Guidance needed on recent HIV prevention findings

"In the absence of the anticipated guidance from WHO, the euphoria felt by participants at Rome that the latest science can allow us for the first time to consider eliminating HIV was tempered by utter confusion among program managers as to what to do next," Nathan Ford, medical coordinator for Medecins Sans Frontiere's International Campaign for Access to Essential Medicines, writes in the PLoS "Speaking of Medicine" blog.

25 Jul 2011

Nanoviricides lead anti-HIV candidate as good as HAART cocktail therapy

NanoViricides, Inc. reports that its lead anti-HIV candidate achieved anti-HIV efficacy equivalent to a HAART triple drug cocktail in its recently completed animal study.

25 Jul 2011

Better targeting of pharmaceuticals to patient's genetic profile could save around $110B annually

Genetic testing made possible by the mapping of the human genome can help the US cut costs and create jobs while at the same time improving survival rates for such diseases as cancer, HIV, and heart disease.

25 Jul 2011

NAACP, AHF offer free HIV and STD testing at Los Angeles Convention Center

On Saturday, July 23, 2011 from 2:00 PM to 6:00 PM, please join AIDS Healthcare Foundation and the NAACP with free HIV rapid testing and testing for other STDs, including gonorrhea, chlamydia and syphilis.

25 Jul 2011

House committee votes to reinstate 'global gag rule' on abortion

The House Foreign Affairs Committee on Thursday voted to "reinstate a ban on providing foreign aid to groups that perform abortions or provide advice about the procedure," The Hill's "HealthWatch" blog reports on the "so-called 'global gag rule'".

25 Jul 2011

Circumcision prevents HIV transmission & cocktail of anti-HIV drugs prolong life

Reports came in last Wednesday that circumcision reduces transmission of HIV, in regions where transmission is high. To researchers, this procedure proves to be a cost-effective way to handle the pandemic. In South Africa, a study reported that men with circumcisions reduced new HIV infections by 76%.

24 Jul 2011

IAS conference concludes with positive news on HIV prevention

"Scientists on Wednesday wrapped up their biggest forum in the 30-year history of AIDS, unveiling stunning weapons to prevent the spread of HIV," Agence France-Presse reports about the 6th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention in Rome.

22 Jul 2011

Financial Times examines product development partnerships developing drugs for neglected diseases

The Financial Times examines the rise of product development partnerships (PDPs), which are "non-governmental organizations that generate their own funding and build partnerships with universities, businesses, government and patients in low-income countries to develop new drugs, vaccines, prevention techniques and diagnostics for diseases such as tuberculosis, HIV, malaria, cholera and meningitis."

22 Jul 2011

UK regulators approve Europe's first clinical trial of plant-derived antibody for HIV

UK regulators have approved Europe's first clinical trial of a monoclonal antibody produced from genetically modified plants. This landmark decision sets the stage for the testing, in humans, of an anti-HIV product made from genetically modified tobacco plants. It will open the door for trials of additional plant-derived medicines treating a range of diseases.

22 Jul 2011

Abbott's AACC workshops to showcase HIV and vitamin D diagnostics, lab informatics

Abbott announced its schedule of key workshops and scientific presentations at the American Association for Clinical Chemistry (AACC) annual meeting, July 24-28 in Atlanta.

22 Jul 2011

FDA approves U.S. launch of Wiskott-Aldrich gene therapy clinical trial

The U.S. Food & Drug Administration (FDA) approved the launching in the U.S. of a clinical trial for gene therapy for a rare immunodeficiency, Wiskott-Aldrich syndrome.

22 Jul 2011

HIV-infected MSM more likely to contract HCV through sex

Sexual transmission of hepatitis C virus (HCV) is considered rare. But a new study by researchers at Mount Sinai School of Medicine, working with the Centers for Disease Control and Prevention (CDC), provides substantial evidence that men with HIV who have sex with other men (MSM) are at increased risk for contracting HCV through sex.

22 Jul 2011

NIDA awards $3.5M to BUSM/BMC for 'Linking Infectious and Narcology Care' project

Researchers from the Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) were recently awarded a $3.5 million grant from the National Institute on Drug Abuse (NIDA), to improve upon the "seek, test, treat, and retain" paradigm in Eastern Europe among HIV-infected Russian and Eastern European injection drug users (IDUs) in narcology care.

22 Jul 2011

NIAID awards $36M grant to BIDMC for AIDS vaccine research in nonhuman primates

Beth Israel Deaconess Medical Center (BIDMC) has been awarded a grant from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, to lead a Consortium for AIDS Vaccine Research in Nonhuman Primates.

21 Jul 2011

Cell biologists identify infection mechanism of adenoviruses

Mucosal epithelia do not have any receptors on the outer membrane for the absorption of viruses like hepatitis C, herpes, the adenovirus or polio, and are thus well-protected against pathogenic germs. However, certain viruses, such as the human immunodeficiency virus HIV, still manage to enter the body via the mucous membrane.

21 Jul 2011

WHO warning increases opportunity for Biomagnetics urine based TB assay

Biomagnetics Diagnostics Corp., a developer of revolutionary diagnostic systems and technology for HIV, hepatitis, tuberculosis and malaria detection, and other innovative technologies, today announced that the World Health Organization ("WHO") on Sunday July 17, 2011 warned that the widely used blood tests to detect tuberculosis ("TB") are unreliable and "dangerous" to patients because they produce too many false negatives and positives.

21 Jul 2011

Women in embattled regions have limited access and means to use contraceptives

Violent conflict disrupts all aspects of society, including the delivery of the most basic reproductive health services: prenatal and maternal care, family planning, prevention of HIV and other sexually transmitted infections, abortions and emergency caesarian care.

21 Jul 2011

Clinical study of anti-HIV antibody made from genetically modified tobacco plants

Pharmaceuticals can be produced by plants. Antibodies that have been produced in tobacco plants will now for the first time be tested in a clinical study.

21 Jul 2011

Boosted REYATAZ shows durable viral suppression in women with HIV

Bristol-Myers Squibb Company announced results from a long-term, retrospective, European cohort study, which included 1,294 antiretroviral (ARV)-experienced patients from Germany, France and Sweden, that were presented today at the Sixth International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention.

21 Jul 2011