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Smoking makes it harder for brain blood flow to recover from long-term heavy drinking

Alcohol-use disorders (AUDs) can damage the brain, particularly the frontal and parietal cortices, although this damage is at least partially reversible with sustained abstinence from alcohol. Chronic smoking is extremely common among individuals with AUDs.

12 May 2009

New genetic clues to treatment of hypertension

An international research team has identified a number of unsuspected genetic variants associated with systolic blood pressure (SBP), diastolic blood pressure (DBP), and hypertension (high blood pressure), suggesting potential avenues of investigation for the prevention or treatment of hypertension.

12 May 2009

Building a bridge from Alzheimer's disease to diabetes and vice versa

Modern societies face the increasing burden of age-related diseases, in particular Alzheimer's disease (AD) and type 2 diabetes (T2D).

12 May 2009

FHL2 protein regulates blood vessel maintenance

In a study led by Akiko Hata, PhD, of Tufts University School of Medicine, researchers have shown that a protein expressed in the heart, FHL2, inhibits the genes necessary for the quiescence of vascular smooth muscle cells (vSMCs), which line blood vessels.

12 May 2009

Discovery of eight previously unknown genes that affect blood pressure

Eight previously unknown genes that affect blood pressure were recently identified in a comprehensive international study comprising 34,433 Europeans. The findings of the study, in which Uppsala University researchers participated, are being presented in the Web edition of Nature Genetics.

11 May 2009

Seniors need more sun!

Spending more time in the sunshine could help older people to reduce their risk of developing heart disease and diabetes.

11 May 2009

Self-reported diagnosis of heart disease: Less than one in five heart problems are diagnosed before symptoms appear

Clinicians are missing golden opportunities to identify heart disease before patients start displaying symptoms, according to a study of 13,877 people published in the May issue of UK-based IJCP, the International Journal of Clinical Practice.

11 May 2009

Muscular dystrophy diagnosis delayed in boys

Boys show signs of Duchenne Muscular Dystrophy (DMD) for 2 ½ years before they obtain a diagnosis and disease-specific treatment, about the same length of delay children have endured for the past 20 years despite advances in genetic testing and treatment.

11 May 2009

Discovery of major new treatment target in diseased arteries

Removing a single protein prevents early damage in blood vessels from triggering a later-stage, frequently lethal complication of atherosclerosis, according to research published online today in the journal Nature Medicine. By eliminating the gene for a signaling protein called cyclophilin A (CypA) from a strain of mice, researchers were able to provide complete protection against abdominal aortic aneurysm (AAA).

11 May 2009

Vibration plate machines may aid weight loss and trim abdominal fat

New research suggests that, if used properly, vibration plate exercise machines may help you lose weight and trim the particularly harmful belly fat between the organs.

10 May 2009

FDA approves Samsca tablets (tolvaptan) to treat hyponatremia

The U.S. Food and Drug Administration has approved Samsca tablets (tolvaptan) to treat hyponatremia, an abnormally low concentration of sodium in the blood.

8 May 2009

FDA approves Avastin (bevacizumab) for treatment of glioblastoma multiforme

The U.S. Food and Drug Administration recently approved Avastin (bevacizumab) to treat patients with glioblastoma multiforme (GBM) when this form of brain cancer continues to progress following standard therapy.

7 May 2009

British scientists win grant to develop hand-held self-monitoring test for HIV viral loads

Scientists in the United Kingdom have received a grant worth two million euros, or about $2.67 million, to develop a self-monitoring system for HIV-positive people that measures viral loads through a finger-prick of blood, BBC News reports.

7 May 2009

Study reveals current multi-component vaccines may need reworking

Current strategies for designing vaccines against HIV and cancers, for instance, may enable some components in multi-component vaccines to cancel the effect of others on the immune system, eliminating their ability to provide protection, according to an article to be published shortly in the Proceedings of the National Academy of Sciences (PNAS).

7 May 2009

New device for patients too sick for open-heart surgery

An innovative device that acts like a belt to reshape an enlarged, leaky heart valve is providing a minimally invasive treatment option for patients who are too sick for open-heart surgery.

7 May 2009

Hypoglycemia poses a serious health threat for patients with chronic kidney disease

Low blood sugar, or hypoglycemia, poses a serious health threat for patients with chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN).

7 May 2009

Kidney disease patients reap rewards of prevention

Making sure you see your doctor and have tests run on a regular basis can prevent serious complications of chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN).

7 May 2009

2010 budget for FDA invests substantially in food and medical product safety

The U.S. Food and Drug Administration, part of the U.S. Department of Health and Human Services, is requesting a budget of $3.2 billion to protect and promote the public health as part of the President's fiscal year (FY) 2010 budget - a 19 percent increase over the current FDA fiscal year budget.

7 May 2009

Research confirms benefits of mobile health screening program to help diagnose at-risk populations

Results presented today at the American Society of Hypertension's Twenty Fourth Annual Scientific Meeting (ASH 2009) reveal that hypertension is still disproportionally prevalent in African-American women living in Boston’s inner city neighborhoods, despite recent improvements in diagnostic and treatment options.

7 May 2009

Low blood pressure may increase risk of heart attack and stroke

Data from the Treating to New Targets (TNT) trial presented today at the American Society of Hypertension's Twenty Fourth Annual Scientific Meeting (ASH 2009) show that low blood pressure levels may lead to increased risk of cardiovascular events, including heart attack and stroke. These data supplement previous findings from the TNT trial of atorvastatin showing aggressive LDL cholesterol-lowering reduced cardiovascular events.

7 May 2009