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Researchers find direct link between oxidative stress and inflammatory signals in the blood

The finding could lead to improved strategies for preventing several diseases by including antioxidants in the diet and for reducing the impact of inflammation in critically ill patients by adding cysteine to intravenous or tube feeding.

30 Mar 2009

Increased awareness and diagnosis of celiac disease would bring health care costs savings

A study published in Journal of Insurance Medicine by members of the Celiac Disease Center at Columbia University Medical Center has demonstrated an economic benefit to the diagnosis of celiac disease in a national managed-care population in the United States.

30 Mar 2009

Discovery of new tumor suppressor gene

National Institutes of Health (NIH) researchers have identified a gene that suppresses tumor growth in melanoma, the deadliest form of skin cancer.

30 Mar 2009

Corthera's Relaxin in acute heart failure shows promising results

Corthera Inc. has announced that results from Pre-RELAX-AHF, the Phase II portion of a Phase II/III multicenter, randomized, double-blind, placebo-controlled international study, demonstrated promising efficacy and safety for relaxin, the company's investigational drug for treatment of acute heart failure (AHF).

30 Mar 2009

Drug-coated stents lower risk of heart attack and death

Heart disease patients 65 and older who receive stents coated with medicine to prevent blockages are more likely to survive and less likely to suffer a heart attack than people fitted with stents not coated with medication, according to a new study supported by HHS' Agency for Healthcare Research and Quality and the American College of Cardiology's National Cardiovascular Data Registry.

30 Mar 2009

Angiogenesis inhibitor improves glioblastoma survival by reducing edema

The beneficial effects of anti-angiogenesis drugs in the treatment of the deadly brain tumors called glioblastomas appear to result primarily from reduction of edema - the swelling of brain tissue - and not from any direct anti-tumor effect, according to a study from Massachusetts General Hospital (MGH) researchers.

30 Mar 2009

Gene linked to lupus might explain why females are 10 times more susceptible to the disease

In an international human genetic study, researchers at UT Southwestern Medical Center have identified a gene linked to the autoimmune disease lupus, and its location on the X chromosome might help explain why females are 10 times more susceptible to the disease than males

30 Mar 2009

New marker for breast cancer metastasis

Researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center have identified a new marker for breast cancer metastasis called TMEM, for Tumor Microenvironment of Metastasis.

30 Mar 2009

New Lantheus study finds significant survival benefit for critically ill patients undergoing contrast-enhanced echocardiography

Lantheus Medical Imaging, Inc has announced new data regarding the use of DEFINITY Vial For (Perflutren Lipid Microsphere) Injectable Suspension.

29 Mar 2009

NTRILIPIX (fenofibric acid) in combo with Rosuvastatin calcium shows improvement on key lipids for cholesterol management

Data from a new study showed that Abbott's TRILIPIX (fenofibric acid) delayed-release capsules in combination with rosuvastatin calcium met all of the study's primary endpoints.

29 Mar 2009

Improved predictive value of biomarkers in HF makes earlier diagnosis and better management possible

With an ever ageing population and more people surviving a heart attack, heart failure is now the world's most prevalent chronic cardiovascular disease.

29 Mar 2009

Improved predictive value of biomarkers in heart failure now makes earlier diagnosis and better management possible

With an ever ageing population and more people surviving a heart attack, heart failure is now the world's most prevalent chronic cardiovascular disease.

29 Mar 2009

How fat is stored may explain lower rate of liver disease in African-Americans

Where different ethnic groups store fat in their bodies may account for differences in the likelihood they'll develop insulin resistance and non-alcoholic fatty liver disease, researchers at UT Southwestern Medical Center have found.

29 Mar 2009

ARCA biopharma presents data from phase 3 BEST trial of Gencaro

ARCA biopharma, Inc. has announced that data from the pivotal Phase 3 BEST trial of Gencaro (bucindolol hydrochloride) in patients with advanced chronic heart failure (CHF) was presented at the American College of Cardiology 58 th Annual Scientific Session being held March 29-31, 2009 in Orlando, Florida.

29 Mar 2009

Dapagliflozin trial results indicate improvement in key glycemic measures in treatment-naive type 2 diabetes

Findings published in Diabetes Care from a 12-week, Phase IIb dose-ranging study showed that dapagliflozin, a novel, selective, sodium glucose co-transporter2 (SGLT2) inhibitor, produced clinically meaningful reductions across all key glycemic measures studied [glycosylated hemoglobin level (HbA1c), fasting plasma glucose (FPG), and postprandial plasma glucose (PPG)] in treatment-naive type 2 diabetes patients, compared to placebo.

29 Mar 2009

CRESTOR (rosuvastatin) shown to significantly reduce risk of venous thromboembolism

A new analysis from the JUPITER study shows that CRESTOR (rosuvastatin) 20mg significantly cut the risk of venous thromboembolism (VTE) by 43% (p=0.007) compared to placebo among men and women with low to normal cholesterol levels and elevated high-sensitivity C-reactive protein (hsCRP).

29 Mar 2009

Preferences, beliefs and self-management of diabetes

People with diabetes who feel they have better control over life events are more likely to take good care of themselves and to believe they have the condition under control, but these factors do not translate to improved blood sugar levels, according to a new study of 1,034 adults.

29 Mar 2009

Blood News and Research

Researchers find direct link between oxidative stress and inflammatory signals in the blood

Increased awareness and diagnosis of celiac disease would bring health care costs savings

Discovery of new tumor suppressor gene

Corthera's Relaxin in acute heart failure shows promising results

Drug-coated stents lower risk of heart attack and death

Angiogenesis inhibitor improves glioblastoma survival by reducing edema

Gene linked to lupus might explain why females are 10 times more susceptible to the disease

New marker for breast cancer metastasis

New Lantheus study finds significant survival benefit for critically ill patients undergoing contrast-enhanced echocardiography

NTRILIPIX (fenofibric acid) in combo with Rosuvastatin calcium shows improvement on key lipids for cholesterol management

Improved predictive value of biomarkers in HF makes earlier diagnosis and better management possible

Improved predictive value of biomarkers in heart failure now makes earlier diagnosis and better management possible

How fat is stored may explain lower rate of liver disease in African-Americans

ARCA biopharma presents data from phase 3 BEST trial of Gencaro

Dapagliflozin trial results indicate improvement in key glycemic measures in treatment-naive type 2 diabetes

CRESTOR (rosuvastatin) shown to significantly reduce risk of venous thromboembolism

Preferences, beliefs and self-management of diabetes

Amicus Therapeutics presents positive results from phase 2 extension study of Amigal for Fabry disease

Clinical effectiveness of coronary stents in the elderly

Difference in fat storage may explain lower rate of liver disease in African-Americans

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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