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Shining light on diabetic retinopathy

A group of scientists in California is trying to develop a cheaper, less invasive way to spot the early stages of retinal damage from diabetic retinopathy, the leading cause of blindness in American adults, before it leads to blindness.

11 Mar 2009

Scientists unveil a new path towards better immune responses

The immune response can protect us from basically any invader but it can also create disease - like it happens in autoimmunity where it attacks the own body - so to understand its regulation is an important tool to assure its proper functioning.

11 Mar 2009

Study of Rituxan (rituximab) in lupus nephritis misses primary endpoint

Genentech, Inc. and Biogen Idec has announced that a Phase III study of Rituxan (rituximab) plus mycophenolate mofetil (MMF) and corticosteroids in patients with lupus nephritis did not meet its primary endpoint of significantly reducing disease activity at 52 weeks.

11 Mar 2009

Mandatory obstructive sleep apnea screenings could reduce risk of truck crashes

Truck crashes are a significant public health hazard causing thousands of deaths and injuries each year, with driver fatigue and sleepiness being major causes.

11 Mar 2009

Novel anti-inflammatory therapy protects lungs from runaway inflammation

A novel anti-inflammatory therapy designed by Vanderbilt University Medical Center investigators prevents acute lung injury in mice exposed to an inflammation-causing toxin, the researchers report in the journal Molecular Therapy.

11 Mar 2009

Low levels of vitamin D linked to several risk factors in teenagers

Low levels of vitamin D were associated with an increased risk of high blood pressure, high blood sugar and metabolic syndrome in teenagers, researchers reported at the American Heart Association's 49th Annual Conference on Cardiovascular Disease Epidemiology and Prevention.

11 Mar 2009

Trends in heart attack explained

Explaining trends in heart attack: prevention has improved, mortality rates are down, hospitalisation remains the same

11 Mar 2009

Consuming a little less salt could mean fewer deaths

For every gram of salt that Americans reduce in their diets daily, a quarter of a million fewer new heart disease cases and over 200,000 fewer deaths would occur over a decade, researchers said at the American Heart Association's 49th Annual Conference on Cardiovascular Disease Epidemiology and Prevention.

11 Mar 2009

Teenage stress carries forward to adulthood

Most of us remember our teenage years with a mix of fondness and relief. Fondness for the good memories, and relief that all that teenage stress, angst and drama - first love, gossip, SATs, fights with parents - is behind us.

11 Mar 2009

Salt could be 'nature's antidepressant' according to new research

Most people consume far too much salt, and a University of Iowa researcher has discovered one potential reason we crave it: it might put us in a better mood.

11 Mar 2009

10 million people in the U.S. suffer from lower-limb peripheral arterial disease

According to iData Research, an international medical device & dental market research firm, an estimated 10 million people in the U.S. suffer from lower-limb Peripheral Arterial Disease (PAD), with less than 20% of these diagnosed by a physician.

11 Mar 2009

Financial incentives stimulate changes in medical practice

A large group of California physicians given financial incentives to improve the quality of medical care have begun to embrace an array of changes important to advancing quality, according to a RAND Corporation study issued today.

11 Mar 2009

Small molecules block cancer gene

Finding molecules that block the activity of the oncogene Stat 3 (signal transducer and activator of transcription) required screening literally millions of compounds, using computers that compared the structure of the cancer-causing gene to those of the small molecules, said a Baylor College of Medicine researcher in a report that appears in the current online issue of the journal PLoS One (Public Library of Science ONE).

11 Mar 2009

Simple test helps predict heart attack risk

The use of common and readily available screening tests - like the ankle brachial index (ABI) - along with traditional risk scoring systems - such as the Framingham Risk Score - has the potential to prevent devastating heart attacks in thousands of individuals who are not originally thought to be at high risk (according to Framingham alone), say researchers at the Society of Interventional Radiology's 34th Annual Scientific Meeting.

11 Mar 2009

'Seeing' stem cells helps in fight against peripheral arterial disease

Interventional radiologists are fitting together the puzzle pieces of how to use stem cells to create new or more blood vessels to treat peripheral arterial disease (PAD) in those individuals with extensively narrowed or clogged arteries.

11 Mar 2009

Scientists discover key molecules that inhibit viral production

The research, led by Professor Donny Strosberg of Scripps Florida, was published on March 4, 2009, in the Journal of General Virology's advance, online edition, Papers in Press.

11 Mar 2009

SOX9 protein may be a potential target for melanoma treatment

In a new study released today, researchers have shown that a specific protein plays an important role in inhibiting the development and spread of melanoma tumors in mouse and in human skin models.

11 Mar 2009

Discovery of new mechanism the malaria parasite uses to enter human red blood cells

Virginia Commonwealth University Life Sciences researchers have discovered a new mechanism the malaria parasite uses to enter human red blood cells, which could lead to the development of a vaccine cocktail to fight the mosquito-borne disease.

11 Mar 2009

Saving limbs with drug-eluting stents

Attempts to treat critical limb ischemia in peripheral arterial disease (PAD) patients with below-the-knee angioplasty are still thwarted by restenosis (the re-narrowing of the artery at the site of angioplasty or stenting), the need for repeat treatments and the continued progression of atherosclerotic disease, leading to tissue death (gangrene) and amputation.

11 Mar 2009

Interventional radiology makes complicated C-sections safer

Innovative, interventional radiology treatments are making childbirth safer for women who have C-sections that are complicated by massive bleeding and for those who suffer from the pregnancy condition of "invasive" placenta.

11 Mar 2009