Immune System News and Research

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Shortage of coronavirus 'cure' puts pregnant lupus sufferers and their babies at risk

Pregnant lupus sufferers and their babies are at risk as global supplies of an anti-malarial medicine used to treat the disease run dry due to COVID-19 panic.

24 Apr 2020

Active ingredient from parasite larvae could help treat asthma

The larvae of the roundworm Heligmosomoides polygyrus bakeri (Hpb) need a very special environment in order to survive: They have to invade the mucosal layer of the intestine in rodents, the only place where they can then develop into adult worms capable of reproduction.

24 Apr 2020

Syphilis bacterium likely uses a single gene to evade immune attack

The bacterium that causes syphilis, Treponema pallidum, likely uses a single gene to escape the immune system, research from UW Medicine in Seattle suggests.

24 Apr 2020

Vaping, opioid addiction accelerate coronavirus risks, says NIDA director

In 2018, opioid overdoses claimed about 47,000 American lives. Last year, federal authorities reported that 5.4 million middle and high school students vaped. And just two months ago, about 2,800 cases of vaping-associated lung injuries resulted in hospitalizations; 68 people died.

24 Apr 2020

Research shows how the immune system reacts to hepatitis C viruses

If a virus penetrates a cell, the immune system reacts immediately and produces the signaling protein interferon.

24 Apr 2020

Goblet cells in the human nasal passage may play key role in enabling COVID-19 infections

Two significant international studies involving hundreds of scientists, including a human geneticist at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that specific cells in the human nasal passage shaped like a champagne glass, known as goblet cells, may play a significant role in enabling COVID-19 infections.

24 Apr 2020

Combination therapy boosts the immune system's appetite for cancer

A combination of immunotherapy agents that encourages some immune cells to eat cancer cells and alert others to attack tumors put mice with a deadly type of brain cancer called glioblastoma into long-term remission, a new study led by UT Southwestern scientists suggests.

24 Apr 2020

Study: JNK and BNP activity can reverse cardiovascular damage, reduce risk of death from sepsis

Overreaction is rarely useful, and in the case of the human immune system, it can be outright deadly. When the body overreacts to an infection, the result is sepsis - a life-threatening condition that frequently leads to acute organ dysfunction, including deterioration of the heart and blood vessels, which make up the cardiovascular system.

24 Apr 2020

Dietary supplements are effective and low-cost means to fight COVID-19

Supplements containing vitamins C and D and other micronutrients, sometimes in amounts exceeding the federally recommended levels, are a safe, effective and low-cost means of helping your immune system fight off COVID-19 and other acute respiratory tract diseases, an Oregon State University researcher says.

24 Apr 2020

First COVID-19-related clinical trial to start in Germany

German regulators have approved the first clinical trial of a coronavirus vaccine. Developed by BioNTech SE, an immunotherapy company, and Pfizer, a pharmaceutical company, the potential coronavirus vaccine has completed pre-clinical studies in Germany.

24 Apr 2020

Coronavirus may cause sudden stroke in younger patients, doctors warn

Older adults and those with underlying medical conditions are at risk of experiencing severe coronavirus disease (COVID-19). Younger people appeared to experience only mild illness, but doctors warn that the viral infection may cause sudden strokes.

23 Apr 2020

New nanobiosensor can help diagnose early-stage multiple sclerosis

Researchers at the Federal University of São Carlos in Sorocaba have developed a technique to diagnose early-stage multiple sclerosis, a disease of the central nervous system, and distinguish it from neuromyelitis optica, a rare yet severe autoimmune inflammatory process also affecting the central nervous system.

23 Apr 2020

Link between BCG and lower COVID-19 mortality disproved by new analysis

The association between BCG (Bacillus Calmette-Guérin) vaccination and its purported beneficial effect on COVID-19 transmission/mortality rates was challenged in an expert appraisal of Diamond Princess cruise ship data. At the same time, cross-national differences previously reported were shown to be flawed, reports a new medRxiv study.

23 Apr 2020

EPFL scientists identify new therapeutic target for Non-Hodgkin lymphoma

Non-Hodgkin lymphoma is a group of cancers that originate in the lymph nodes and affect white blood cells of the immune system called B cells.

23 Apr 2020

Study identifies key nose cells as likely COVID-19 virus entry points

Two specific cell types in the nose have been identified as likely initial infection points for COVID-19 coronavirus. Scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that the COVID-19 virus uses to get into our cells.

23 Apr 2020

Genomic sequencing shows COVID-19 spread patterns

Throughout the spread of the virus, genomic sequencing has played a role in epidemiologic tracking of the viral strains carried all over the world. Such strains are traced back to their origin by their unique mutations and help to link remote infections.

22 Apr 2020

Using 'own' immune cells to fight infectious diseases including COVID-19

A provocative paper from Duke-NUS Medical School, published in the Journal of Experimental Medicine in March 2020, discusses the possibilities of creating new receptors on a sick person's own immune cells as a means of controlling the infection. This therapy is already being used to treat certain cancers with marked success.

22 Apr 2020

Hyperferritinemia associated with increased illness severity in COVID-19

Yehuda Shoenfeld is the world's leading expert in the research, treatment and prevention of autoimmune diseases.

22 Apr 2020

Study creates a new platform to study single-cell genomics of many diseases

Although advances in genetics and genomics reveal numerous disease-associated gene mutations, physicians and researchers still wrestle with the tricky challenge of linking those mutations to actual disease-causing processes.

22 Apr 2020

Antibody testing in L.A. county reveals the magnitude of coronavirus spread

After weeks of physical and social distancing measures in place, many in the U.S. are worrying about how soon they can return to normal life. However, to lift restrictions, it is critical to ascertain accurate numbers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) carriers. Doing so will decrease the chance or even avoid the second wave of infections.

22 Apr 2020