Antibodies News and Research

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How next-gen sequencing is changing antibody drug discovery

New study outlines how next-generation sequencing (NGS) and machine-learning methods can revolutionize antibody discovery, particularly against SARS-CoV-2. The research demonstrates that NGS provides greater epitopic and paratopic diversity, enabling more effective identification and prioritization of therapeutic antibodies.

31 Oct 2023

AI may help identify potential gonorrhea vaccine proteins

Gonorrhea, a sexually transmitted bacterial infection that affects more than 80 million people worldwide every year, has become resistant to almost all known antibiotics.

31 Oct 2023

Scientists identify mechanism causing deadly blood clots after some COVID-19 vaccines

A mechanism that led some patients to experience cases of deadly clotting following some types of Covid-19 vaccination has been identified in new research.

30 Oct 2023

New classification criteria for antiphospholipid syndrome

APS is a systemic autoimmune disease associated with persistent antiphospholipid antibodies (aPL). It can cause thrombosis and pregnancy complications as well as non-thrombotic manifestations such as cardiac valve disease.

30 Oct 2023

Study unveils new approach to more precise, long-lasting, and less toxic cancer treatment

For too long, cancer treatment has been a double-edged sword – the very treatments designed to kill cancer cells often wrought havoc on healthy ones too.

30 Oct 2023

New antibody may offer effective drug treatment for breast cancer

An enzyme that may help some breast cancers spread can be stopped with an antibody created in the lab of Cold Spring Harbor Laboratory Professor Nicholas Tonks.

30 Oct 2023

Diabetic patients with COVID-19: low antibody levels linked to worse outcomes

The role of anti-SARS-CoV-2 antibody levels on COVID-19 outcomes in patients with T2D.

30 Oct 2023

SARS-CoV-2 antigens stick around: Study finds virus markers can linger for over a year

Researchers found that SARS-CoV-2 antigens can persist in the body for up to 14 months after initial infection, challenging the idea that COVID-19 is a transient illness. This finding has implications for understanding long-term effects of the virus and could influence future treatments and vaccines.

30 Oct 2023

MHRA grants conditional marketing authorization for AbbVie's Tepkinly to treat aggressive blood cancer

AbbVie today announced that the UK Medicines and Healthcare products Regulatory Agency has granted conditional Marketing Authorisation for Tepkinly® (epcoritamab) as a monotherapy for the treatment of adults with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL), after two or more systemic therapies.

28 Oct 2023

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

An international Phase 3 clinical trial found that metastatic colorectal cancer patients with a rare genetic tumor mutation called KRAS G12C experienced superior progression-free survival rates compared to standard of care when offered a combination treatment of KRAS inhibitor sotorasib and monoclonal antibody panitumumab.

27 Oct 2023

Microbubble-based biomarker could improve NIR-PIT treatment for cancer

Researchers at Nagoya University in Japan and their collaborators have used a biomarker based on microbubbles to evaluate the success of near-infrared photoimmunotherapy (NIR-PIT) treatment.

26 Oct 2023

Malaria protein discovery opens new avenues for combating deadly infection

The discovery of a malaria protein that helps the parasite grow inside red blood cells and plays a key regulatory role in the parasite's immune evasion tactics could pave the way for new vaccines or therapeutics to combat the deadly infection.

26 Oct 2023

City of Hope, TGen receive $4.5 million to validate liquid biopsy for early detection of pancreatic cancer

City of Hope, one of the largest cancer research and treatment organizations in the United States, and TGen are leading an international group that has been awarded $4.5 million to validate a liquid biopsy for the early detection of pancreatic cancer.

26 Oct 2023

How strep bacteria outsmart your immune system and why it matters for treatment

Researchers discover that Group A streptococcal infections alter immunoglobulin G (IgG) homeostasis to evade the immune system, affecting the transition from local to systemic infections. The study also raises concerns about the effectiveness of antibody-based therapies, as the bacteria's virulence factors can degrade therapeutic antibodies.

25 Oct 2023

Oxford Vaccine Group launches a pioneering study into human immunity

This study will test the responses of cells in lymph nodes before and after immunization with flu and COVID-19 vaccines and compare reactions in older and younger adults.

25 Oct 2023

Omicron's edge: boosters pressure SARS-CoV-2 to adapt and evolve

The effects of vaccine booster doses on the adaptive evolution of the virus.

25 Oct 2023

BA.2.86 Omicron sub-variant shows high receptor affinity but moderate neutralization resistance

Study investigates the receptor affinity and antigenicity of the SARS-CoV-2 Omicron BA.2.86 variant, revealing that it does not show higher resistance to neutralization by human sera than other recent variants. Despite its high number of mutations and receptor affinity, the variant is slightly more sensitive to neutralization than the EG.5.1 variant, warranting continued surveillance.

24 Oct 2023

Recombinant rabies virus vaccine with molecular adjuvant induces strong immune responses and protection in mice

This study aimed to improve the effectiveness of the rabies vaccine to help alleviate and eliminate the rabies epidemic.

24 Oct 2023

Researchers discover new way to trigger programmed cell death in cancer cells

A research team from the UC Davis Comprehensive Cancer Center has identified a crucial epitope (a protein section that can activate the larger protein) on the CD95 receptor that can cause cells to die.

24 Oct 2023

Study sheds light on role of gut fungi in severe COVID-19 and long COVID

Certain gut-dwelling fungi flourish in severe cases of COVID-19, amplifying the excessive inflammation that drives this disease while also causing long-lasting changes in the immune system, according to a new study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian.

24 Oct 2023

Antibodies News and Research

How next-gen sequencing is changing antibody drug discovery

AI may help identify potential gonorrhea vaccine proteins

Scientists identify mechanism causing deadly blood clots after some COVID-19 vaccines

New classification criteria for antiphospholipid syndrome

Study unveils new approach to more precise, long-lasting, and less toxic cancer treatment

New antibody may offer effective drug treatment for breast cancer

Diabetic patients with COVID-19: low antibody levels linked to worse outcomes

SARS-CoV-2 antigens stick around: Study finds virus markers can linger for over a year

MHRA grants conditional marketing authorization for AbbVie's Tepkinly to treat aggressive blood cancer

New treatment combination shows promise for metastatic colorectal cancer patients with rare genetic mutation

Microbubble-based biomarker could improve NIR-PIT treatment for cancer

Malaria protein discovery opens new avenues for combating deadly infection

City of Hope, TGen receive $4.5 million to validate liquid biopsy for early detection of pancreatic cancer

How strep bacteria outsmart your immune system and why it matters for treatment

Oxford Vaccine Group launches a pioneering study into human immunity

Omicron's edge: boosters pressure SARS-CoV-2 to adapt and evolve

BA.2.86 Omicron sub-variant shows high receptor affinity but moderate neutralization resistance

Recombinant rabies virus vaccine with molecular adjuvant induces strong immune responses and protection in mice

Researchers discover new way to trigger programmed cell death in cancer cells

Study sheds light on role of gut fungi in severe COVID-19 and long COVID

How to make hybridoma-based antibody discovery more efficient eBook

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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