Dexamethasone News and Research

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Revlimid receives approval in Switzerland for treatment of multiple myeloma

Celgene International Sarl has announced that it's oral cancer drug, Revlimid (lenalidomide) has been granted approval by the Swiss Agency for Therapeutic Products (Swissmedic) for use in combination with dexamethasone as a treatment for patients with multiple myeloma who have received at least one prior therapy.

5 Sep 2007

High altitude pulmonary oedema

Experts at the University are studying an illness known as HAPE (high altitude pulmonary oedema), which causes fluid to build up in the lungs can and can occur from as low as 2,500 metres, affecting people of all age groups and fitness levels.

22 Aug 2007

Inhaled nitric oxide safe for very premature infants

A nationwide study led by researchers at UCSF provides evidence that inhaled nitric oxide is safe and effective for the prevention of the most common type of long-term lung disease of very premature infants.

7 Aug 2007

Treating bronchiolitis with steroids doesn't work

For infants with a common and potentially serious viral lower respiratory infection called bronchiolitis, a widely used steroid treatment is not effective.

27 Jul 2007

Dexamethasone steroid treatment shows no benefit for kids with bronchiolitis

DMC Children's Hospital of Michigan has found that a common steroid treatment often prescribed for kids with bronchiolitis has no impact on improving their symptoms or in reducing hospitalization.

26 Jul 2007

Steroid medications don't work in treating lower respiratory infections in children

The use of steroid medication to treat bronchiolitis, a common viral lower respiratory infection in infants , does not prevent hospitalization or improve their respiratory symptoms, according to a study published in the July 26 issue of The New England Journal of Medicine.

26 Jul 2007

New hope for common form of childhood cancer

Dr. Richard Lock, Head of the Leukaemia Biology Program at the Children's Cancer Institute Australia for Medical Research, Sydney, along with collaborators from the Childrens Hospital Los Angeles and University of Southern California, USA, recently published their findings in the prestigious scientific journal Blood.

23 Jul 2007

New hope for childhood cancer sufferers

Scientists investigating drug therapies for children with Acute Lymphoblastic Leukaemia (ALL) have presented new data demonstrating for the very first time that a small molecule called ABT-737 can increase the effectiveness of standard therapies.

17 Jul 2007

Myeloma cancer drug gets the green light from the EU

The European Union has given the green light to a drug which doubles the survival rates for people with myeloma.

21 Jun 2007

Revlimid may change the way physicians treat multiple myeloma

Findings from a Phase III study by the Eastern Cooperative Oncology Group (ECOG 4A03) were presented yesterday at the American Society of Clinical Oncology (ASCO) meeting in Chicago and demonstrate the benefits of using Revlimid (lenalidomide) with reduced doses of the steroid dexamethasone.

5 Jun 2007

Patients with myelodysplastic syndromes treated with Revlimid are living longer and remaining transfusion independent

New updated results from a pivotal Phase II trial evaluating Revlimid in patients with an incurable blood cancer known as myelodysplastic syndromes (MDS) were presented by Dr. Alan List, from the H. Lee Moffitt Cancer Center & Research Institute, at the 9th International Symposium on MDS currently taking place in Florence, Italy.

18 May 2007

Multiple myeloma dexamethasone / lenalidomide trial closes

The Southwest Oncology Group, the largest of several National Cancer Institute-sponsored clinical trials networks, has permanently closed enrollment in a trial comparing a standard drug therapy, dexamethasone, with a combined therapy of the same drug plus the drug lenalidomide (Revlimid) for people newly diagnosed with multiple myeloma.

16 May 2007

Chaetocin shows promise as a new anti-myeloma agent

Mayo Clinic Cancer Center researchers have found that chaetocin, a by-product of a common wood mold, has promise as a new anti-myeloma agent. Results of their study, being presented today at the American Association for Cancer Research annual meeting, show the by-product to be more effective than currently used therapies at killing multiple myeloma cells.

16 Apr 2007

Lower doses of dexamethasone for multiple myeloma recommended

The International Myeloma Foundation (IMF) - supporting research and providing education, advocacy and support for myeloma patients, families, researchers and physicians - today said physicians should consider lowering the dose of the steroid dexamethasone when treating patients with multiple myeloma.

5 Apr 2007

Multiple myeloma trial has shows significant improvement in survival

Mayo Clinic Cancer Center has announced that a multiple myeloma clinical trial has shown a significant improvement in survival with lenalidomide plus low-dose dexamethasone therapy compared to lenalidomide plus high-dose dexamethasone.

5 Apr 2007

Preemie lung treatments turn out to be safe

Preemies between 28 and 32 weeks are not harmed by a treatment no longer used to help their lungs mature before birth, according to findings of a study in this month's Pediatrics.

5 Mar 2007

Chemotherapy drug bortezomib packs a one-two punch

Cancer can be wily, and those who treat the disease have amassed a wide array of weapons with which to fight it and kill tumors.

20 Feb 2007

Prospective cardiac monitoring in fetuses at risk of congenital heart block

There is an increased risk of fetal heart problems when mothers carry particular antibodies associated with rheumatic diseases, according to an abstract presented by Yale School of Medicine researchers at the Society for Maternal-Fetal Medicine Conference in San Francisco.

11 Feb 2007

Drugs given to stop nausea and vomiting after surgery help only a few people

Between 10 - 28% of people benefit from taking an anti-emetic drug to prevent nausea or vomiting after surgery - this means that if everyone was given the drug the majority of patients would be exposed to the risk of side-effects without gaining any benefit.

19 Jul 2006

Drugs for preventing postoperative nausea and vomiting

Patients coming out of anesthesia after surgery may experience nausea or vomiting, and are frequently given drugs to prevent this. But the majority of patients won't benefit from these drugs, according to a large new review of studies.

19 Jul 2006