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Penn State Hershey cardiologist explains causes and symptoms of heart attack

It's possible to have a heart attack and not even know it. Maybe it's because you're stoic when it comes to pain and fatigue. Or maybe you write off your symptoms as heartburn or indigestion. It's even possible that your own body is kicking up its reserves to mask symptoms of what is happening inside.

9 Jul 2015

Janssen-sponsored Phase 2b trial shows guselkumab effective in treating moderate to severe plaque psoriasis

Results published today in The New England Journal of Medicine from a Janssen Research & Development, LLC (Janssen)-sponsored Phase 2b trial showed up to 86 percent of patients with moderate to severe plaque psoriasis receiving guselkumab (CNTO 1959) achieved a Physician's Global Assessment (PGA) score of cleared psoriasis or minimal psoriasis at week 16, the study's primary endpoint.

9 Jul 2015

Researchers find way to measure the aging process in young adults

An international research team from the US, UK, Israel and New Zealand has found a way to measure the aging process in young adults -- a younger population than is usually tested in aging studies.

9 Jul 2015

NSU cancer researcher selected for prestigious J. William Fulbright award

Nova Southeastern University cancer researcher Appu Rathinavelu, Ph.D., was selected for a prestigious J. William Fulbright award to conduct cancer research and training in India. Dr. Rathinavelu is associate dean for institutional planning and development at NSU's College of Pharmacy and executive director of NSU's Rumbaugh-Goodwin Institute for Cancer Research.

9 Jul 2015

Ludwig, CRI launch clinical trials to evaluate immunotherapies for treatment of GBM and solid tumors

Ludwig Cancer Research and the Cancer Research Institute have launched clinical trials evaluating an immunotherapy for the treatment of the brain cancer glioblastoma multiforme (GBM), and a combination of immunotherapies for a variety of solid tumors.

8 Jul 2015

LUX-Lung 8 supports afatinib in squamous NSCLC

Compared with erlotinib, treatment with afatinib leads to outcomes in previously treated patients with advanced squamous non-small-cell lung cancer, suggest the results of a head-to-head trial.

8 Jul 2015

Study aims to determine utility of Trovagene's PCM technology for predicting response to cancer immunotherapy

Trovagene, Inc., a developer of cell-free molecular diagnostics, today announced the launch of a study that aims to determine utility of the Company's Precision Cancer Monitoring (PCM) technology for predicting response to treatment in advanced melanoma patients receiving one or a combination of the novel immunotherapy agents Yervoy (ipilumumab), a CTLA-4 inhibitor, and Opdivo (nivolumab), a PD-1 inhibitor.

8 Jul 2015

Adolescents more likely to try e-cigarettes when exposed to TV ads

Adolescents who are exposed to e-cigarette TV advertising are more likely to try e-cigarettes in the future, according to a groundbreaking experiment from researchers at RTI International. Although advertising and adolescent use of e-cigarettes have simultaneously increased in recent years, this is the first study to demonstrate a direct link between adolescents' exposure to advertising and their likelihood of future use.

8 Jul 2015

WSU researcher secures $1.25 million NIH grant to study role of rosiglitazone drug in reversing preeclampsia

Sascha Drewlo, Ph.D., assistant professor of obstetrics and gynecology for the Wayne State University School of Medicine, has secured a $1.25 million grant from the National Heart, Lung and Blood Institute of the National Institutes of Health to study the role of approved drugs to improve placental function.

8 Jul 2015

Researchers develop novel technique to generate activated T cells to tackle advanced melanoma

T cells from patients with melanoma can trigger a protective immune response against the disease according to a new study out of University Hospitals Case Medical Center Seidman Cancer Center and Case Western Reserve University School of Medicine.

8 Jul 2015

University of Adelaide researchers develop laser system for onsite breath analysis

University of Adelaide researchers are developing a laser system for fast, non-invasive, onsite breath analysis for disease, potentially enabling screening for a range of diseases including diabetes, infections and various cancers in the future.

8 Jul 2015

New WHO report focuses on raising taxes on tobacco, stamping out tobacco epidemic

Too few governments levy appropriate levels of tax on cigarettes and other tobacco products. They therefore miss out on a proven, low-cost measure to curb demand for tobacco, save lives and generate funds for stronger health services, according to the "WHO Report on the global tobacco epidemic 2015".

7 Jul 2015

EPFL scientists identify lansoprazole as potential candidate against tuberculosis

Testing thousands of approved drugs, EPFL scientists have identified an unlikely anti-tuberculosis drug: the over-the-counter antacid lansoprazole (Prevacid).

7 Jul 2015

Findings reveal new pathway to develop effective treatments and therapies for asthma, allergy

Investigators have discovered the precise molecular steps that enable immune cells implicated in certain forms of asthma and allergy to develop and survive in the body. The findings from Weill Cornell Medical College reveal a new pathway that scientists could use to develop more effective treatments and therapies for the chronic lung disorder.

7 Jul 2015

New portable system can produce life-saving NO from air by means of electrical spark

Treatment with inhaled nitric oxide (NO) has proven to be life saving in newborns, children and adults with several dangerous conditions, but the availability of the treatment has been limited by the size, weight and complexity of equipment needed to administer the gas and the therapy's high price.

7 Jul 2015

Study uncovers complicated role of simple protein in spread of osteosarcoma

The investigation of a simple protein has uncovered its uniquely complicated role in the spread of the childhood cancer, osteosarcoma. It turns out the protein, called ezrin, acts like an air traffic controller, coordinating multiple functions within a cancer cell and allowing it to endure stress conditions encountered during metastasis.

7 Jul 2015

Transitioning Infrared Imaging into Clinical Use

The CLIRSPEC network is a UK Engineering and Physical Sciences Research Council (EPSRC – EP/L012952/1) funded network in clinical infrared and Raman spectroscopy. Infrared and Raman spectroscopy can identify the hallmarks of disease and distinguish between diseased and non-diseased samples based upon inherent chemistry.

From Daylight Solutions Inc 7 Jul 2015

Celtaxsys receives FDA clearance to begin acebilustat Phase 2 trial in adult CF patients in the US

Celtaxsys, Inc., a clinical stage pharmaceutical development company focusing on anti-inflammatory therapeutics, including those with rare and orphan inflammatory disease indications, announced today that it has gained clearance from the U.S. Food and Drug Administration to begin a Phase 2 clinical trial of its flagship drug candidate, acebilustat (CTX-4430), in adult CF patients in the US.

7 Jul 2015

Boehringer Ingelheim LUX-Lung 8 trial reveals afatinib better than erlotinib to treat SCC of the lung

Boehringer Ingelheim today announced The Lancet Oncology has published results from the LUX-Lung 8 trial. LUX-Lung 8 is the largest, prospective Phase III head-to-head trial directly comparing two EGFR-directed treatments.

6 Jul 2015

Researchers analyze cardiometabolic benefits of exercise

Everyone knows that exercise generally helps the cardiovascular system, but much remains unknown about how the benefits arise, and what to expect in different people who exercise to improve their health. To gain a more precise understanding of how exercise improves health and whom it helps most, researchers analyzed the results of 160 randomized clinical trials with nearly 7,500 participants.

3 Jul 2015

Lungs News and Research

Penn State Hershey cardiologist explains causes and symptoms of heart attack

Janssen-sponsored Phase 2b trial shows guselkumab effective in treating moderate to severe plaque psoriasis

Researchers find way to measure the aging process in young adults

NSU cancer researcher selected for prestigious J. William Fulbright award

Ludwig, CRI launch clinical trials to evaluate immunotherapies for treatment of GBM and solid tumors

LUX-Lung 8 supports afatinib in squamous NSCLC

Study aims to determine utility of Trovagene's PCM technology for predicting response to cancer immunotherapy

Adolescents more likely to try e-cigarettes when exposed to TV ads

WSU researcher secures $1.25 million NIH grant to study role of rosiglitazone drug in reversing preeclampsia

Researchers develop novel technique to generate activated T cells to tackle advanced melanoma

University of Adelaide researchers develop laser system for onsite breath analysis

New WHO report focuses on raising taxes on tobacco, stamping out tobacco epidemic

EPFL scientists identify lansoprazole as potential candidate against tuberculosis

Findings reveal new pathway to develop effective treatments and therapies for asthma, allergy

New portable system can produce life-saving NO from air by means of electrical spark

Study uncovers complicated role of simple protein in spread of osteosarcoma

Transitioning Infrared Imaging into Clinical Use

Celtaxsys receives FDA clearance to begin acebilustat Phase 2 trial in adult CF patients in the US

Boehringer Ingelheim LUX-Lung 8 trial reveals afatinib better than erlotinib to treat SCC of the lung

Researchers analyze cardiometabolic benefits of exercise

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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