Immune System News and Research

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Novel drug combination shows promise for treating advanced skin cancers in kidney transplant recipients

People who have had a kidney transplant are at high risk for developing skin cancers. New research directed by investigators from the Johns Hopkins Kimmel Cancer Center is exploring the best combination of treatments to target skin cancers while preserving the transplanted organs.

28 Feb 2024

Novel brain organoid model unveils link between inflammation and astrocyte dysfunction

The brain is typically depicted as a complex web of neurons sending and receiving messages. But neurons only make up half of the human brain.

28 Feb 2024

UMass Amherst study targets aplastic anemia with cell retraining approach

Researchers at the University of Massachusetts Amherst recently released a first-of-its-kind study that focuses on the rare autoimmune disorder aplastic anemia to understand how a subset of cells might be trained to correct the overzealous immune response that can lead to fatal autoimmune disorders.

27 Feb 2024

Study finds metabolic checkpoint PHGDH as potential target to modulate tumor-associated macrophages

A study by a scientific team from the University of Vienna and the MedUni Vienna, recently published in the top-class journal Cellular & Molecular Immunology, has a promising result from tumor research: The enzyme phosphoglycerate dehydrogenase (PHDGH) acts as a metabolic checkpoint in the function of tumor-associated macrophages (TAMs) and thus on tumor growth.

27 Feb 2024

Boston College biologist wins NIH grant to study viral insulins for cancer treatment

Boston College Assistant Professor of Biology Emrah Altindis has been awarded a five-year, $2.5-million grant from the National Institutes of Health to study viral insulins and mechanisms related to IGF-1 receptor protein inhibition and its potential applications in cancer treatment.

26 Feb 2024

Innovative therapy targets and destroys leukemia stem cells

Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States, have devised an innovative approach to target and destroy hard-to-kill leukemia stem cells.

26 Feb 2024

New clinical practice guideline offers evidence-based recommendations for managing inhalant allergies with immunotherapy

The American Academy of Otolaryngology–Head and Neck Surgery Foundation published the Clinical Practice Guideline: Immunotherapy for Inhalant Allergy today in Otolaryngology–Head and Neck Surgery.

26 Feb 2024

Study: Antibody combination shows safety and anti-tumor activity in advanced cancer patients

In an early phase clinical trial, a combination of antibody-based medications targeting the immune system generated promising safety data and anti-tumor activity in individuals with various types of advanced cancer.

26 Feb 2024

Omalizumab shows promise in preventing food allergy reactions in children, study finds

A drug can make life safer for children with food allergies by preventing dangerous allergic responses to small quantities of allergy-triggering foods, according to a new study led by scientists at the Stanford School of Medicine.

25 Feb 2024

Newborn T cells found to excel in immune defense

Scientists have long believed that a newborn's immune system was an immature version of an adult's, but new research from Cornell University shows that newborns' T cells – white blood cells that protect from disease – outperform those of adults at fighting off numerous infections.

24 Feb 2024

Researchers develop promising recombinant flu vaccine using nanoliposome technology

Recombinant protein vaccines, like the Novavax vaccine used to fight COVID-19, offer several advantages over conventional vaccines.

24 Feb 2024

Identifying antiviral protein IFN-γ as a potential biomarker for Long COVID

SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache and depression. New research shows that in Long COVID patients, IFN-y production persists until symptoms improve, highlighting a potential biomarker and a target for therapies.

24 Feb 2024

Unlocking vitamin B6's role in pancreatic cancer and immune system battle

Vitamin B6 is beneficial in many ways, notably for its role in maintaining a strong immune system. However, when pancreatic cancer develops, its cells also need vitamin B6 to replicate.

23 Feb 2024

Understanding the role played by HIV in pulmonary hypertension

Across the globe, more than 39 million people are living with the Human Immunodeficiency Virus (HIV), the virus that causes AIDS, including more than 1.3 million new HIV diagnoses last year.

23 Feb 2024

Novel approach uses patient's cells as "trojan horse" to target lung cancer cells

Lung cancer is not the most common form of cancer, but it is by far the deadliest.

23 Feb 2024

Genetic signature may help predict disease-free survival in patients with non-small cell lung cancer

A new study identified a set of 140 genes that may help predict enhanced disease-free survival in patients with non-small cell lung cancer (NSCLC) treated with a combination of immunotherapy and low-dose radiation.

23 Feb 2024

Research reveals bacteria's dynamic defense duo against phage viruses

Scientists at the University of Southampton have discovered that bacteria can pair up their defense systems to create a formidable force, greater than the sum of its parts, to fight off attack from phage viruses.

23 Feb 2024

Neutrophil reprogramming promotes tumor growth in certain cancers

A new research study led by A*STAR.Singapore Immunology Network (A*STAR.SIgN) has found that neutrophils-;one of the most abundant white blood cells in our body-;change drastically in certain cancers, adopting a new function whereby they promote tumour growth.

23 Feb 2024

Breakthrough discovery offers hope for reducing infections in cystic fibrosis patients

University of Queensland researchers have identified an opportunity to reduce infections in people living with cystic fibrosis.

22 Feb 2024

Off-the-shelf cancer vaccine shows promising results in patients with KRAS-mutated tumors

Samara Rahman, 74, considers herself lucky. She gets to take walks on the beach, go swimming and ride her bike -; all things that were taken from her when she was diagnosed with pancreatic cancer in November of 2022.

22 Feb 2024

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Immune System News and Research

Novel drug combination shows promise for treating advanced skin cancers in kidney transplant recipients

Novel brain organoid model unveils link between inflammation and astrocyte dysfunction

UMass Amherst study targets aplastic anemia with cell retraining approach

Study finds metabolic checkpoint PHGDH as potential target to modulate tumor-associated macrophages

Boston College biologist wins NIH grant to study viral insulins for cancer treatment

Innovative therapy targets and destroys leukemia stem cells

New clinical practice guideline offers evidence-based recommendations for managing inhalant allergies with immunotherapy

Study: Antibody combination shows safety and anti-tumor activity in advanced cancer patients

Omalizumab shows promise in preventing food allergy reactions in children, study finds

Newborn T cells found to excel in immune defense

Researchers develop promising recombinant flu vaccine using nanoliposome technology

Identifying antiviral protein IFN-γ as a potential biomarker for Long COVID

Unlocking vitamin B6's role in pancreatic cancer and immune system battle

Understanding the role played by HIV in pulmonary hypertension

Novel approach uses patient's cells as "trojan horse" to target lung cancer cells

Genetic signature may help predict disease-free survival in patients with non-small cell lung cancer

Research reveals bacteria's dynamic defense duo against phage viruses

Neutrophil reprogramming promotes tumor growth in certain cancers

Breakthrough discovery offers hope for reducing infections in cystic fibrosis patients

Off-the-shelf cancer vaccine shows promising results in patients with KRAS-mutated tumors

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