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Stable nanoparticles train the immune system to fight cancer

Over the past decade, researchers have sought more effective and enduring cancer treatments. Among the wide variety of immunotherapies, Stimulator of Interfron Genes activation (STING agonism) has emerged as a particularly promising approach that harnesses a patient’s immune system to combat tumors throughout the body.

17 Jul 2023

Neighborhood environment can increase risk of COVID-19 hospitalization, study reveals

The range of COVID-19 symptoms varies-;some feel a mild cold, others are hospitalized, while others perish. Many studies have linked the severity of COVID-19 symptoms with an individual's biological factors, but less is known about the impact of non-biological factors, such as the environment in which people live.

14 Jul 2023

Intensive exercise slows the course of Parkinson's disease, study finds

Neuroscientists from the Faculty of Medicine of the Catholic University, Rome Campus, and the A. Gemelli IRCCS Polyclinic Foundation found that intensive exercise could slow the course of Parkinson's disease and described the biological mechanisms.

14 Jul 2023

Study describes the scope and integration of music therapy program within UH medical centers

A new study from University Hospitals (UH) Connor Whole Health describes the scope and integration of their music therapy program within10 UH medical centers.

14 Jul 2023

Aerobic glycolysis essential for eye development in mammals, study finds

Aerobic glycolysis, the process by which cells transform glucose into lactate, is key for eye development in mammals, according to a new Northwestern Medicine study published in Nature Communications.

14 Jul 2023

BU professor receives NIH grant to study impact of PFAS toxicants on the vascular system

Noyan Gokce, MD, professor of medicine at Boston University Chobanian & Avedisian School of Medicine, has been awarded a $453,750 National Institutes of Health (NIH) R-21 grant for his research study "Impact of Per/Polyfluoroalkyl (PFAS) pollutants on vascular disease mechanisms."

14 Jul 2023

Black residents in highly segregated neighborhoods have shorter life expectancies, study finds

Black residents living in highly segregated neighborhoods have significantly shortened life expectancies, reports a new Northwestern Medicine study.

14 Jul 2023

Insilico Medicine and MIKADO team up to find new treatments for cystinosis

A team led by researchers at the Mechanisms of Inherited Kidney Disorders (MIKADO) group at the University of Zurich (Zurich, Switzerland) has used Insilico Medicine's generative artificial intelligence (AI) target discovery engine, PandaOmics, to identify actionable drug targets for the lysosomal storage disease cystinosis and to validate them in preclinical models of the disease.

14 Jul 2023

Antibodies: More than just a key-lock mechanism

Antibodies are crucial, not only for treating tumors and infections. Sometimes, however, the immune reaction they trigger can be too strong and end up causing more damage, for example in the case of people infected with Covid-19.

14 Jul 2023

New lipid 'signature' could help identify women at risk of preeclampsia

University of Virginia School of Medicine researchers have discovered a way to identify pregnant women at risk of preeclampsia, a serious disorder characterized by high blood pressure and kidney dysfunction which can result in premature delivery, seizures and even death.

14 Jul 2023

AI-powered drug discovery offers hope for cystinosis patients

Artificial intelligence is becoming increasingly important in drug discovery. Advances in the use of Big Data, learning algorithms and powerful computers have now enabled researchers at the University of Zurich (UZH) to better understand a serious metabolic disease.

14 Jul 2023

Exercise can improve quality of life and reduce hospitalizations for dialysis patients

Patients who engage in light exercise while undergoing dialysis are physically fitter and are admitted to hospital less frequently than those who do not.

14 Jul 2023

UW Medicine surgeons saved a patient with dual-organ transplant

Doctors in Seattle are reporting a history-making case in which a patient received two donor organs, a liver and a heart, to prevent the extreme likelihood that her body would reject a donor heart transplanted alone.

14 Jul 2023

New drug could overcome resistance to CDK4/6 inhibitors in breast cancer

Brest cancer is the most common cancer in women. Among breast tumors that spread to other organs (develop metastasis), 70% belong to a variant, called luminal, whose cells are sensitive to the female sex hormones estrogen and progesterone. In fact, the tumor forms when these hormones order the cells to divide.

14 Jul 2023

Scientists discover new mechanism for kidney cell renewal

University of Texas at Dallas scientists have discovered a previously unknown "housekeeping" process in kidney cells that ejects unwanted content, resulting in cells that rejuvenate themselves and remain functioning and healthy.

14 Jul 2023

ChatGPT shows promise in addressing heart failure queries with accuracy and precision

Researchers evaluate the accuracy and reproducibility of responses from ChatGPT in answering heart failure-related questions.

14 Jul 2023

Study highlights lack of gold standard for measuring asthma control in pediatric patients

Researchers compared questionnaires assessing asthma control measures in children in primary care.

14 Jul 2023

Multidisciplinary quality improvement project reduces infant hypothermia rates

The percentage of infants from the neonatal intensive care unit (NICU) experiencing hypothermia upon operating room (OR) arrival and at any point during the operation decreased from 48.7% to 6.4% and 67.5% to 37.4%, respectively, after implementation of a multidisciplinary quality improvement project at Ann & Robert H. Lurie Children's Hospital of Chicago.

13 Jul 2023

Synoptic reports improve completeness of pretreatment CT reports in advanced ovarian cancer

According to an accepted manuscript published in the American Journal of Roentgenology (AJR), a synoptic report improved completeness of pretreatment CT reports in patients with advanced ovarian cancer, including for established sites of unresectable or challenging-to-resect disease.

13 Jul 2023

Combination therapy shows promise in treating advanced ER+ breast cancer

Advanced estrogen receptor-positive (ER+) breast cancer can be especially difficult to treat. A new study by researchers at Dartmouth Cancer Center led by Todd W. Miller, PhD, shows promise in using a combination of estrogen and a PARP inhibitor (a drug that suppresses DNA damage repair), to treat this type of cancer.

13 Jul 2023

Medicine News and Research

Stable nanoparticles train the immune system to fight cancer

Neighborhood environment can increase risk of COVID-19 hospitalization, study reveals

Intensive exercise slows the course of Parkinson's disease, study finds

Study describes the scope and integration of music therapy program within UH medical centers

Aerobic glycolysis essential for eye development in mammals, study finds

BU professor receives NIH grant to study impact of PFAS toxicants on the vascular system

Black residents in highly segregated neighborhoods have shorter life expectancies, study finds

Insilico Medicine and MIKADO team up to find new treatments for cystinosis

Antibodies: More than just a key-lock mechanism

New lipid 'signature' could help identify women at risk of preeclampsia

AI-powered drug discovery offers hope for cystinosis patients

Exercise can improve quality of life and reduce hospitalizations for dialysis patients

UW Medicine surgeons saved a patient with dual-organ transplant

New drug could overcome resistance to CDK4/6 inhibitors in breast cancer

Scientists discover new mechanism for kidney cell renewal

ChatGPT shows promise in addressing heart failure queries with accuracy and precision

Study highlights lack of gold standard for measuring asthma control in pediatric patients

Multidisciplinary quality improvement project reduces infant hypothermia rates

Synoptic reports improve completeness of pretreatment CT reports in advanced ovarian cancer

Combination therapy shows promise in treating advanced ER+ breast cancer

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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