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African cancer genome registry seeks to understand disparities in prostate, breast cancer risk and outcomes

"Please, please do it (cancer screening), if not for yourself, then for the next generation. We need to see the day when we end cancer."

11 Jul 2023

Study uncovers neurons that track, regulate blood-sugar levels

New research has discovered neurons within the brain which detect and respond to changes in the level of sugar within the bloodstream.

11 Jul 2023

Whole genome sequencing shows promise for early diagnosis of genetic disorders in newborns, infants

A new national study, led by researchers at Tufts Medical Center in Boston, has found whole genome sequencing (WGS) to be nearly twice as effective as a targeted gene sequencing test at identifying abnormalities responsible for genetic disorders in newborns and infants.

11 Jul 2023

New mouse model mimics the development of frailty in older adults

Researchers at the Johns Hopkins University School of Medicine have developed a mouse model that successfully mimics the development of frailty as mammals — likely including people — get older.

11 Jul 2023

Natural language processing used to extract social determinants of health

Information on the nonmedical factors that influence health outcomes, known as social determinants of health, is often collected at medical appointments.

11 Jul 2023

Columbia researchers develop first fully organic bioelectronic device

As researchers make major advances in medical care, they are also discovering that the efficacy of these treatments can be enhanced by individualized approaches.

10 Jul 2023

Majority of dying patients in UK hospitals have unmet needs

People dying in UK hospitals without specialist palliative care input frequently have "significant and poorly identified unmet needs," finds a UK-wide evaluation-;the first of its kind-;published online in the journal BMJ Supportive & Palliative Care.

10 Jul 2023

Women with certain job roles may be associated with heightened risk of ovarian cancer

Hairdressers, beauticians, and accountants are among certain job roles that may be associated with a heightened risk of ovarian cancer, finds a case-control study published online in the journal Occupational & Environmental Medicine.

10 Jul 2023

Acute kidney injury does not predict worsening kidney function trajectory in CKD patients

A study of hospitalized persons with chronic kidney disease (CKD) fournd that acute kidney injury (AKI) did not predict worsening of kidney function trajectory once difference in pre-hospitalization characteristically were fully accounted for.

10 Jul 2023

Using misinformation and hate to harm the most vulnerable members of society

In an Editor's Statement in the peer-reviewed journal Transgender Health on the importance of access to gender affirming care for our nation's youth, Journal Editor-in-Chief Robert Garofalo, MD, MPH, states "LGBTQ youth need love, support, and acceptance, not misinformation and hate thinly veiled as compassion."

10 Jul 2023

New clinical trial seeks a regenerative pharmaceutical solution for meniscal tears

With support from Amplicore, a University of Cincinnati spinoff biopharmaceutical company, researchers at UC have begun a Department of Defense-funded clinical trial that seeks a regenerative pharmaceutical solution for meniscal tears.

10 Jul 2023

Bystander CPR and defibrillation rates increase dramatically with volunteer responder systems

People suffering from sudden cardiac arrest are more likely to survive if cardiopulmonary resuscitation (CPR) and automated external defibrillators (AED) are used as soon as possible. However, in an out-of-hospital setting survival rates are low due to delays in care and low uptake of bystander CPR and AED use.

10 Jul 2023

Phosphorothioate backbone modification enhances aptamer-drug conjugate for pancreatic cancer therapy

Pancreatic cancer is a complex and deadly solid tumor that poses significant challenges for both diagnosis and treatment.

10 Jul 2023

AMP releases consensus recommendations for CYP3A4 and CYP3A5 genotyping assays

The Association for Molecular Pathology (AMP), the premier global molecular diagnostic professional society, today published consensus recommendations to aid in the design and validation of clinical CYP3A4 and CYP3A5 genotyping assays, promote standardization of testing across different laboratories, and improve patient care.

10 Jul 2023

High tumor monocyte content linked to better outcomes for esophageal cancer patients

A Ludwig Cancer Research study has discovered that the presence of relatively high numbers of immune cells known as monocytes in tumors is linked to better outcomes in esophageal cancer patients treated with a combination of chemotherapy and immunotherapy, or immunochemotherapy.

10 Jul 2023

Alcohol-related hepatitis hospitalizations increased dramatically during the pandemic

A boom in alcohol sales during the pandemic appears to have had dire consequences for some as hospital admissions for alcohol-related hepatitis, a life-threatening liver inflammation, increased dramatically, according to a study of national hospitalization data.

10 Jul 2023

Biomarkers in the brain could redefine mental health conditions

The study of biomarkers in the brain-;powered by cutting-edge machine learning techniques-;could redefine the way mental health conditions are categorized and diagnosed and lead to more effective, personalized treatments.

10 Jul 2023

Study: Flavor restrictions could make major progress in fighting youth vaping epidemic

Major progress could be made in fighting the youth vaping epidemic with a complete restriction on sweet flavorings and cooling agents in both cartridge and disposable e-cigarette devices, according to a new study from the Center for Tobacco Research at The Ohio State University Comprehensive Cancer Center.

10 Jul 2023

Few studies highlight the effects of lifestyle interventions on postpartum blood pressure

Hypertensive disorders of pregnancy such as preeclampsia and gestational hypertension occur in up to 10% of pregnancies and are associated with a three-fold increased risk of chronic hypertension and up to two-fold increased risk of cardiovascular disease when compared with healthy pregnancies.

10 Jul 2023

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

Two anti-inflammatory drugs, abatacept and infliximab, reduced deaths among patients hospitalized with severe COVID-19, according to a national study led by Washington University School of Medicine in St. Louis. William G. Powderly, MD, (right) who led the large clinical trial, discusses patient conditions with Maanasi Samant, MD, in the intensive care unit at Barnes-Jewish Hospital, one of the major trial sites, during the COVID-19 pandemic.

10 Jul 2023

Medicine News and Research

African cancer genome registry seeks to understand disparities in prostate, breast cancer risk and outcomes

Study uncovers neurons that track, regulate blood-sugar levels

Whole genome sequencing shows promise for early diagnosis of genetic disorders in newborns, infants

New mouse model mimics the development of frailty in older adults

Natural language processing used to extract social determinants of health

Columbia researchers develop first fully organic bioelectronic device

Majority of dying patients in UK hospitals have unmet needs

Women with certain job roles may be associated with heightened risk of ovarian cancer

Acute kidney injury does not predict worsening kidney function trajectory in CKD patients

Using misinformation and hate to harm the most vulnerable members of society

New clinical trial seeks a regenerative pharmaceutical solution for meniscal tears

Bystander CPR and defibrillation rates increase dramatically with volunteer responder systems

Phosphorothioate backbone modification enhances aptamer-drug conjugate for pancreatic cancer therapy

AMP releases consensus recommendations for CYP3A4 and CYP3A5 genotyping assays

High tumor monocyte content linked to better outcomes for esophageal cancer patients

Alcohol-related hepatitis hospitalizations increased dramatically during the pandemic

Biomarkers in the brain could redefine mental health conditions

Study: Flavor restrictions could make major progress in fighting youth vaping epidemic

Few studies highlight the effects of lifestyle interventions on postpartum blood pressure

Two anti-inflammatory drugs reduce deaths in severe COVID-19 patients

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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