Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

Scientists discover genetic basis and molecular mechanisms of new neurodevelopmental syndrome

Scientists at the University of North Carolina at Chapel Hill School of Medicine and colleagues have demonstrated that variants in the SPTBN1 gene can alter neuronal architecture, dramatically affecting their function and leading to a rare, newly defined neurodevelopmental syndrome in children.

1 Jul 2021

Novel optical device could open new avenues in advanced microscopy

What if a microscope allowed us to explore the 3D microcosm of blood vessels, nerves, and cancer cells instantaneously in virtual reality? What if it could provide views from multiple directions in real time without physically moving the specimen and worked up to 100 times faster than current technology?

1 Jul 2021

New methodology predicts biological activity of any molecule

The Structural Bioinformatics and Network Biology laboratory, led by ICREA Researcher Dr. Patrick Aloy, has completed the bioactivity information for a million molecules using deep machine-learning computational models. It has also disclosed a tool to predict the biological activity of any molecule, even when no experimental data are available.

29 Jun 2021

RAMBO can cut indexing times for huge DNA databases

Rice University computer scientists are sending RAMBO to rescue genomic researchers who sometimes wait days or weeks for search results from enormous DNA databases.

28 Jun 2021

Study: Odorant receptor recognizes pyrazines in both humans and domesticated animals

A team of scientists from the Leibniz Institute for Food Systems Biology at the Technical University of Munich has now discovered that the odorant receptor OR5K1 is specialized to recognize pyrazines in both humans and domesticated animals.

23 Jun 2021

Molecular study reveals signs of inflammation in brains of people who died of COVID-19

The most comprehensive molecular study to date of the brains of people who died of COVID-19 turned up unmistakable signs of inflammation and impaired brain circuits.

22 Jun 2021

Researchers screen Chinese herbal medicines and plant compounds for anti-SARS-CoV-2 activity

A review published in Phytotherapy Research discussed the natural anti-SARS-CoV-2 products identified based on in silico prediction. The review’s authors also illustrate the impact of many phytochemicals either alone or in combination with traditional treatments and their potential molecular mechanisms involved in SARS-CoV-2 prevention and treatment.

22 Jun 2021

A World First: sequencing polyclonal antibodies using only proteomics

News-Medical speaks to Bin Ma, President of Rapid Novor, about their latest research that sequenced polyclonal antibodies using only proteomics.

From Rapid Novor Inc 21 Jun 2021

First insights into human prion disease could help tackle neurodegenerative diseases

Surface features of human prions have been identified for the first time, which may provide key information into treatments of neurodegenerative diseases.

18 Jun 2021

Presence of certain stem cells linked to nongenetic resistance mechanisms of cancer cells

Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails.

18 Jun 2021

Study finds new clues to explain how Alzheimer’s disease spreads in the brain

Case Western Reserve University researchers studying prions-;misfolded proteins that cause lethal incurable diseases-;have identified for the first time surface features of human prions responsible for their replication in the brain.

18 Jun 2021

UCLA wins $4.8 million NIH grant to develop methods for improving polygenic risk scores

UCLA Health will receive a $4.8 million grant from The National Institutes of Health to develop methods that will improve genetic risk estimates - polygenic risk scores - for specific diseases in people from diverse populations and mixed ancestries.

16 Jun 2021

Studies shed new light on disease processes in tuberculosis

Two new studies have cast unprecedented light on disease processes in tuberculosis, identifying key genetic changes that cause damage in the lungs and a drug treatment that could speed up recovery.

16 Jun 2021

SNPRC at Texas Biomed awarded $37 million NIH grant to continue operations into 2026

The Southwest National Primate Research Center at Texas Biomedical Research Institute has been awarded more than $37 million from the National Institutes of Health to continue operations into 2026.

15 Jun 2021

LSU Health New Orleans receives $2.38 million in funding to sequence SARS-CoV-2 variants

LSU Health New Orleans has been awarded $2.38 million in funding to lead partnerships to sequence SARS-CoV-2 variants.

14 Jun 2021

Delays and shortages hit SARS-CoV-2 genomic surveillance program

A new study from the Institute of Bioinformatics and Applied Biotechnology (IBAB), Bengaluru, India, provides an overview of how well this important monitoring mechanism is functioning around the world. The team has released their findings as a preprint on the bioRxiv* server.

14 Jun 2021

Emerging SARS-CoV-2 variants contain mutations that interfere with genomic sequencing

A recent study by researchers in Canada shows how mutations in newly emerging lineages of SARS-CoV-2 may disrupt the sequencing process and thus interfere with this important area of research.

14 Jun 2021

New gene expression network can help understand mechanism behind continuous stem cell activity in plants

An inter-university research group has succeeded in constructing the gene expression network behind the vascular development process in plants.

11 Jun 2021

AMP’s new consensus can promote standardization of PGx gene/allele testing, improve patient care

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today published consensus recommendations to aid in the design and validation of clinical CYP2D6 assays, promote standardization of testing across different laboratories and improve patient care

11 Jun 2021

Largest U.S. study shares first results on effects of COVID-19 on cancer patients

In the largest study of its kind to date, researchers analyzing national data from more than 63,000 patients with cancer and a positive COVID-19 diagnosis report an increased risk of death among those who were older, male, had a higher number of comorbidities, and had hematologic cancers and recent chemotherapy treatments.

11 Jun 2021

Bioinformatics News and Research

Further Reading

Scientists discover genetic basis and molecular mechanisms of new neurodevelopmental syndrome

Novel optical device could open new avenues in advanced microscopy

New methodology predicts biological activity of any molecule

RAMBO can cut indexing times for huge DNA databases

Study: Odorant receptor recognizes pyrazines in both humans and domesticated animals

Molecular study reveals signs of inflammation in brains of people who died of COVID-19

Researchers screen Chinese herbal medicines and plant compounds for anti-SARS-CoV-2 activity

A World First: sequencing polyclonal antibodies using only proteomics

First insights into human prion disease could help tackle neurodegenerative diseases

Presence of certain stem cells linked to nongenetic resistance mechanisms of cancer cells

Study finds new clues to explain how Alzheimer’s disease spreads in the brain

UCLA wins $4.8 million NIH grant to develop methods for improving polygenic risk scores

Studies shed new light on disease processes in tuberculosis

SNPRC at Texas Biomed awarded $37 million NIH grant to continue operations into 2026

LSU Health New Orleans receives $2.38 million in funding to sequence SARS-CoV-2 variants

Delays and shortages hit SARS-CoV-2 genomic surveillance program

Emerging SARS-CoV-2 variants contain mutations that interfere with genomic sequencing

New gene expression network can help understand mechanism behind continuous stem cell activity in plants

AMP’s new consensus can promote standardization of PGx gene/allele testing, improve patient care

Largest U.S. study shares first results on effects of COVID-19 on cancer patients

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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