Immune System News and Research

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Researchers discover how c-Cbl protein modulates tumor growth

Immune checkpoints are surface proteins that cancer cells use to evade immune response. These surface proteins are critical for cancer cell growth and drugs targeting these proteins have revolutionized the management of patients with a wide array of cancers.

2 Jan 2020

Intravenous BCG vaccine provides greater protection against tuberculosis

Researchers have found that the BCG vaccine is more efficacious in the prevention of TB when administered intravenously.

2 Jan 2020

Top NHS doctor warns of “exploitative” party drips claiming to cure hangovers

NHS England's medical director has warned people against drips being endorsed by celebrities as hangover cures.

2 Jan 2020

New combination of antibodies leads to more effective tumor destruction

The simultaneous use of antibodies based on two differing mechanisms of action leads to a more effective destruction of tumors.

30 Dec 2019

A new deep learning approach to predict disease-associated mutations

During the past years, artificial intelligence (AI) -- the capability of a machine to mimic human behavior -- has become a key player in high-techs like drug development projects.

28 Dec 2019

Study helps explain why previous attempts to develop a staph vaccine have failed

Staph bacteria, the leading cause of potentially dangerous skin infections, are most feared for the drug-resistant strains that have become a serious threat to public health.

26 Dec 2019

CD4 T cells are not to be blamed for pushing dengue fever from bad to worse

No one knows what makes a mild dengue viral infection morph into a severe and sometimes deadly dengue hemorrhagic fever/dengue shock syndrome.

26 Dec 2019

Certain bacteria can override programmed cell death

Certain bacteria can override a defense mechanism of the immune system, so called programmed cell death, through inhibition of death effector molecules by their outer membranes components.

26 Dec 2019

Immunologists discover new RIPK1 mechanism that leads to cell death

Scientists at St. Jude Children's Research Hospital have discovered a new way that the molecule RIPK1 leads to cell death in infected, damaged or unwanted cells showing that more than one mechanism can trigger the process.

23 Dec 2019

California's vaccine policy improved immunization coverage

In 2016, California removed vaccine exemptions for non-medical reasons, such as parental hesitancy, to requirements for school entry. In other words, California children needed to have a medical reason to refuse vaccination if they wanted to join kindergarten. In so doing, the state may have paved the way for a higher percentage of vaccination recipients at both county and state level, says a new study published this week in the journal PLOS Medicine.

23 Dec 2019

Scientists develop 3D atlas of bone marrow to help study blood diseases

The bone marrow, which is the spongy and viscous tissue that fills the bone, is the site of blood cell formation or hematopoiesis. If the bone marrow doesn’t work properly, it can lead to many blood diseases, including leukemia, sickle cell anemia, and lymphoma, among others.

23 Dec 2019

Early-life disruption to lymphotoxin pathway in mice can compromise adult immunity to rotavirus

Researchers at the University of Toronto have discovered how a brief disruption to a molecular pathway in the guts of mice before they are born can compromise adult immunity to a common and often deadly intestinal virus.

22 Dec 2019

New research could lead to an improved vaccine to protect against meningococcal infections

New research from experts at the University of Nottingham could lead to an improved vaccine to protect against the bacterium, Neisseria meningitides that causes sepsis and meningitis.

22 Dec 2019

Developing less aggressive cancer drugs that enable the immune system to recognize tumors

Doctors treat tumors mainly through surgery, radiotherapy, and chemotherapy. Over the next four years, a new project of Bielefeld University and 14 European partners will be studying targeted cancer treatments.

21 Dec 2019

A receptor helps body cells to spot communication amongst bacteria

Bacterial infection does not automatically lead to illness; many germs only become dangerous when they occur in large numbers.

20 Dec 2019

Common immune cell linked to failure of checkpoint inhibitors in lung cancer patients

For many lung cancer patients, the best treatment options involve checkpoint inhibitors. These drugs unleash a patient's immune system against their disease and can yield dramatic results, even in advanced cancers.

19 Dec 2019

New mechanism that impairs Treg differentiation and stability in type 1 diabetes discovered

Regulatory T cells (Tregs) prevent excessive immune reactions in healthy people. In the development of autoimmune type 1 diabetes, this protection is not sufficiently effective.

19 Dec 2019

Severe skin and mucous membrane lesions may occur in children with bacterial pneumonia

Painful inflammatory lesions of the skin and mucous membranes may occur in children who develop bacterial pneumonia.

19 Dec 2019

Scientists create new classification system for tumors

Based on the largest study of cancer patients of its kind, scientists have created a new way of classifying tumors.

19 Dec 2019

Researchers discover a way to move precision immunotherapy forward for multiple myeloma

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way to move precision immunotherapy forward by using genomics to inform immunotherapy for multiple myeloma, a blood cancer, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research, in December.

19 Dec 2019

Immune System News and Research

Researchers discover how c-Cbl protein modulates tumor growth

Intravenous BCG vaccine provides greater protection against tuberculosis

Top NHS doctor warns of “exploitative” party drips claiming to cure hangovers

New combination of antibodies leads to more effective tumor destruction

A new deep learning approach to predict disease-associated mutations

Study helps explain why previous attempts to develop a staph vaccine have failed

CD4 T cells are not to be blamed for pushing dengue fever from bad to worse

Certain bacteria can override programmed cell death

Immunologists discover new RIPK1 mechanism that leads to cell death

California's vaccine policy improved immunization coverage

Scientists develop 3D atlas of bone marrow to help study blood diseases

Early-life disruption to lymphotoxin pathway in mice can compromise adult immunity to rotavirus

New research could lead to an improved vaccine to protect against meningococcal infections

Developing less aggressive cancer drugs that enable the immune system to recognize tumors

A receptor helps body cells to spot communication amongst bacteria

Common immune cell linked to failure of checkpoint inhibitors in lung cancer patients

New mechanism that impairs Treg differentiation and stability in type 1 diabetes discovered

Severe skin and mucous membrane lesions may occur in children with bacterial pneumonia

Scientists create new classification system for tumors

Researchers discover a way to move precision immunotherapy forward for multiple myeloma

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