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Regular use of COX-2 inhibitors may reduce the risk of breast cancer

Results from a new, five-year study show that regular use of popular prescription pain relievers may reduce the risk of breast cancer by up to 71 percent and may offer similar benefit in the prevention of prostate, colon and lung cancers.

4 Apr 2006

Moderate alcohol intake stimulates tumor angiogenesis and expression of vascular endothelial growth factor in a mouse model

University of Mississippi researchers say they have created the first-ever mammalian model of how alcohol consumption spurs tumor growth, showing that even moderate drinking resulted in larger and more robust tumors.

4 Apr 2006

Researchers reverse juvenile diabetes in animal model

Groundbreaking human clinical trial for type 1 diabetes to start this spring in Pittsburgh - Children's Hospital of Pittsburgh of UPMC researchers reverse juvenile diabetes in animal model; Phase 1 clinical trial approved by FDA.

4 Apr 2006

Breakthrough in search for new anti-malarial drugs

Scientists at Drexel University College of Medicine in Philadelphia have made a significant discovery in the fight against malaria. Drexel researchers, along with a research group at the University of Washington, have determined a critical molecular structure of the cellular motor that allows the malaria parasite to invade human cells.

4 Apr 2006

Robotic device appears to be more precise than conventional catheter ablation devices for atrial fibrillation

A remotely-controlled catheter device guided by magnetic fields provides a safe and practical method for delivering radio frequency ablation treatment in the hearts of patients with atrial fibrillation, according to a new study in the April 4, 2006, issue of the Journal of the American College of Cardiology.

4 Apr 2006

Shape and function of the heart improves with apnea treatment

Patients with obstructive sleep apnea have enlarged and thickened hearts that pump less effectively, but the heart abnormalities improve with use of a device that helps patients breathe better during sleep, according to a new study in the April 4, 2006, issue of the Journal of the American College of Cardiology.

4 Apr 2006

Three-dimensional ultrasound probes poised to advance minimally invasive surgery

Three-dimensional ultrasound probes built by researchers at Duke's Pratt School of Engineering have imaged the beating hearts of dogs. The engineers said their demonstration showed that the probes could give surgeons a better view during human endoscopic surgeries in which operations are performed through tiny "keyhole" incisions.

4 Apr 2006

Pigs help study of links between polycystic ovary syndrome, obesity, cardiovascular disease and diabetes

Despite the exaggerated, wrinkly snout and long, coarse, spiky hair reminiscent of the 1980s television space alien ALF, some very special swine are helping researchers at Purdue and Indiana universities understand human infertility, diabetes and cardiovascular disease.

4 Apr 2006

Antioxidant therapy will be useful for women with pre-eclampsia

The antioxidant tempol prevents the onset of pre-eclampsia in pregnant mice, a finding that further implicates oxidative stress in the illness, which is widespread among pregnant women.

4 Apr 2006

Enzymes that harm brain immediately after stroke may be beneficial days later

Insights from the study could change the way stroke is treated, extending the window for effective treatment from a couple of hours to a couple of weeks. The results may suggest new ideas for drug development.

4 Apr 2006

Responding to AIDS, TB, Malaria and emerging infectious diseases in Burma

Government policies in Burma that restrict public health and humanitarian aid have created an environment where AIDS, drug-resistant tuberculosis, malaria and bird flu (H5N1) are spreading unchecked, according to a report by researchers at the Johns Hopkins Bloomberg School of Public Health.

4 Apr 2006

Targeting the inflamed synovium: The quest for specificity

In the April 2006 issue of Arthritis & Rheumatism, noted rheumatology specialists with Kings College London, Dr. Toby Garrood and Dr. Costantino Pitzalis offer an overview of recent breakthroughs and a preview of future directions in this critical quest for specificity.

4 Apr 2006

Targeting of angiogenic endothelial cells at sites of inflammation by Dexamethasone Phosphate-containing RGD peptide liposomes inhibits experimental arthritis

Vascular endothelial cells (VECs) form the walls of blood vessels and play a critical role in inflammation.

4 Apr 2006

Life or death can depend on teenage cancer patients taking their treatments properly

Teenagers and young adults with cancer need to understand the implications of not taking their treatments regularly, at the right time, and for the whole course. Those who don't are seriously compromising their future health - and for some it will be the difference between life and death.

4 Apr 2006

Researchers identify cell cue for destroying tumors

Mayo Clinic researchers have identified and characterized an important signal used by the human immune system to help destroy tumors.

4 Apr 2006

New biomarkers could help detect ovarian cancer much earlier

The search for a specific protein that could help diagnose ovarian cancer in its early stages has for years eluded researchers who are seeking a reliable and accurate test for the disease.

4 Apr 2006

Link between children's sleep-related breathing problems and daytime behavior problems

Hyperactivity, attention deficit, sleepiness, and ADHD often improved - whether or not sleep studies showed sleep apnea before surgery.

4 Apr 2006

Enzyme released by cardiac mast cells during heart attack contributes to arrhythmia

In times of cardiac crisis, mast cells in the heart secrete a powerful enzyme, renin, that indirectly triggers dangerous arrhythmias, according to a team of researchers at the Weill Medical College of Cornell University in New York City.

4 Apr 2006

Cancer chemical scare over soft drinks

Tens of thousands of bottles of soft drinks were removed from shop shelves yesterday after concerns that they could contain a potentially cancer-causing chemical.

3 Apr 2006

Proteomics yields new drug targets for treating cardiogenic shock

When it comes to cell signaling and bioregulation, it's tough to find a more important molecule than nitric oxide (NO). Dysfunction of NO-mediated signaling is thought to be a culprit in lethal cardiovascular conditions such as angina, and septic, cardiogenic and hemorrhagic shock; it may play a role in many other illnesses as well.

3 Apr 2006

Blood News and Research

Regular use of COX-2 inhibitors may reduce the risk of breast cancer

Moderate alcohol intake stimulates tumor angiogenesis and expression of vascular endothelial growth factor in a mouse model

Researchers reverse juvenile diabetes in animal model

Breakthrough in search for new anti-malarial drugs

Robotic device appears to be more precise than conventional catheter ablation devices for atrial fibrillation

Shape and function of the heart improves with apnea treatment

Three-dimensional ultrasound probes poised to advance minimally invasive surgery

Pigs help study of links between polycystic ovary syndrome, obesity, cardiovascular disease and diabetes

Antioxidant therapy will be useful for women with pre-eclampsia

Enzymes that harm brain immediately after stroke may be beneficial days later

Responding to AIDS, TB, Malaria and emerging infectious diseases in Burma

Targeting the inflamed synovium: The quest for specificity

Targeting of angiogenic endothelial cells at sites of inflammation by Dexamethasone Phosphate-containing RGD peptide liposomes inhibits experimental arthritis

Life or death can depend on teenage cancer patients taking their treatments properly

Researchers identify cell cue for destroying tumors

New biomarkers could help detect ovarian cancer much earlier

Link between children's sleep-related breathing problems and daytime behavior problems

Enzyme released by cardiac mast cells during heart attack contributes to arrhythmia

Cancer chemical scare over soft drinks

Proteomics yields new drug targets for treating cardiogenic shock

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