Cell Proliferation News and Research

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Researchers use x-ray crystallography to reveal how curcumin inhibits cancer

Through x-ray crystallography and kinase-inhibitor specificity profiling, University of California San Diego School of Medicine researchers, in collaboration with researchers at Peking University and Zhejiang University, reveal that curcumin, a natural occurring chemical compound found in the spice turmeric, binds to the kinase enzyme dual-specificity tyrosine-regulated kinase 2 at the atomic level.

10 Jul 2018

Genes associated with autism interact to modulate variable symptoms of disease

Genes located in a large chromosomal aberration associated with autism interact with each other to modulate the variable symptoms of the disease, according to new research.

29 Jun 2018

Molecular brake on cell proliferation prevents DNA damage and cancer development

Researchers at Karolinska Institutet, Sweden, and the University of Sussex, England, have discovered that the process of copying DNA generates a brake signal that stalls cell division.

28 Jun 2018

Canadian researchers uncover new molecular mechanism to stop proliferation of cancer cells

Canadian researchers have discovered a new and direct molecular mechanism to stop cancer cells from proliferating. In the prestigious journal Nature Cell Biology, scientists from Université de Montréal show that a disruption of a fine balance in the composition of ribosomes (huge molecules that translate the genetic code into proteins) results in a shutdown of cancer cell proliferation, triggering a process called senescence.

26 Jun 2018

UC Riverside researcher receives grants to advance cancer, ALS research

Maurizio Pellecchia, who holds the Daniel Hays Chair in Cancer Research at the University of California, Riverside, has received two grants to continue his research aimed at finding therapeutics for cancer, amyotrophic lateral sclerosis, and other neurodegenerative diseases.

21 Jun 2018

Scientists discover the molecular trigger of necroptosis

Researchers have uncovered a trigger for an immune-related cell death pathway called necroptosis. The discovery could be used to develop new treatments for cancer and immune disorders.

21 Jun 2018

Study: Oxidative stress can be used against tumors to treat cancer

Oxidative stress can help tumors thrive, but one way novel cancer treatments work is by pushing levels to the point where it instead helps them die, scientists report.

21 Jun 2018

$Study shows fat cells increase in size and number upon exposure to fracking chemicals$

Study shows fat cells increase in size and number upon exposure to fracking chemicals

Exposure to fracking chemicals and wastewater promotes fat cell development, or adipogenesis, in living cells in a laboratory, according to a new Duke University-led study.

21 Jun 2018

Inhibiting epigenetic proteins with drugs could prevent development of breast cancer

Researchers at the Princess Margaret Cancer Centre in Toronto have discovered that epigenetic proteins promote the proliferation of mammary gland stem cells in response to the sex hormone progesterone.

19 Jun 2018

Study opens new potential avenue for treating ovarian cancer

Researchers at Houston Methodist Research Institute and The University of Texas MD Anderson Cancer Center have found a prescription drug, Calcitriol, approved by the Food and Drug Administration for the treatment of calcium deficiency and kidney diseases, may increase the likelihood of surviving ovarian cancer.

14 Jun 2018

New RNA deletion tool could help create drugs that correct genetic diseases

As scientists gain insights into which genes drive diseases, they are pursuing the next logical question: Can gene editing technologies be developed to treat or even cure those diseases? Much of that effort has focused on developing technologies such as CRISPR-Cas9, a protein-based system.

30 May 2018

Flow of cerebrospinal fluid found to be key signal for neural stem cell renewal

Stem cells in the brain can divide and mature into neurons participating in various brain functions, including memory.

21 May 2018

Combination therapies targeting different cell types may be effective at treating colon cancer

Researchers in Germany have discovered that colon cancers are often resistant to existing drug treatments because they are composed of two different cell types that can replace each other when one cell type is killed.

16 May 2018

Study uncovers mechanism underlying brain malformation linked to severe epilepsy

One of the most frequent causes of drug-resistant epilepsy, considered a difficult disease to control, is a brain malformation known as focal cortical dysplasia.

16 May 2018

UCLA researchers characterize mechanism of mEAK-7 gene for the first time

For years, researchers have known that a gene called EAK-7 plays an important role in determining how long worms will live.

15 May 2018

Researchers report advances in efforts to improve treatment, prognosis of colorectal cancers

Georgios Margonis, M.D., Ph.D., a surgical oncology fellow at the Johns Hopkins University School of Medicine, and Matthew Weiss, M.D., surgical director of the Johns Hopkins Liver and Pancreas Cancer Multidisciplinary Clinics, report advances in efforts to improve the treatment and prognosis of colorectal cancers that have spread to the liver.

14 May 2018

Scientists discover potential therapeutic target for devastating premature aging disease

Scientists from the University of Cambridge have identified a potential therapeutic target in the devastating genetic disease Hutchinson-Gilford Progeria Syndrome (HGPS), which is characterized by premature aging.

27 Apr 2018

Specific type of RNA editing plays key role in protein variation in cancer cells, shows research

A multi-center study led by The University of Texas MD Anderson Cancer Center has shed light on why proteins, the seedlings that serve as the incubator for many cancers, can vary from cancer to cancer and even patient to patient, a discovery that adds to a growing base of knowledge important for developing more effective precision therapies.

27 Apr 2018

Researchers use 'top-down proteomics' strategy to get new insights into cancer

When a RAS gene operates normally, it acts as an on/off switch for cell signaling to control cell proliferation. But when the gene mutates, the switch jams into the "on" position, allowing cells to proliferate uncontrollably.

18 Apr 2018

New 'lymphoma micro-reactor' device targets chemo-resistant tumors

Non-Hodgkin lymphoma, a cancer that is diagnosed in the U.S. more than 70,000 times annually, arises from overly proliferating immune cells within the body's lymph nodes, which are connected to a network of lymph vessels through which lymphatic fluid flows.

12 Apr 2018

Cell Proliferation News and Research

Researchers use x-ray crystallography to reveal how curcumin inhibits cancer

Genes associated with autism interact to modulate variable symptoms of disease

Molecular brake on cell proliferation prevents DNA damage and cancer development

Canadian researchers uncover new molecular mechanism to stop proliferation of cancer cells

UC Riverside researcher receives grants to advance cancer, ALS research

Scientists discover the molecular trigger of necroptosis

Study: Oxidative stress can be used against tumors to treat cancer

Study shows fat cells increase in size and number upon exposure to fracking chemicals

Inhibiting epigenetic proteins with drugs could prevent development of breast cancer

Study opens new potential avenue for treating ovarian cancer

New RNA deletion tool could help create drugs that correct genetic diseases

Flow of cerebrospinal fluid found to be key signal for neural stem cell renewal

Combination therapies targeting different cell types may be effective at treating colon cancer

Study uncovers mechanism underlying brain malformation linked to severe epilepsy

UCLA researchers characterize mechanism of mEAK-7 gene for the first time

Researchers report advances in efforts to improve treatment, prognosis of colorectal cancers

Scientists discover potential therapeutic target for devastating premature aging disease

Specific type of RNA editing plays key role in protein variation in cancer cells, shows research

Researchers use 'top-down proteomics' strategy to get new insights into cancer

New 'lymphoma micro-reactor' device targets chemo-resistant tumors

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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