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New TB vaccine: mid-phase trials confirm safety, long-term prevention

A new study published on October 29, 2019, in the New England Journal of Medicine, reports a new vaccine which could change the face of tuberculosis prevention. The disease kills 1.5 million people worldwide each year.

30 Oct 2019

Study uses whole-genome sequencing for early identification and containment of AMR pathogens

A study published today in PNAS examines the evolutionary and epidemiologic history of an epidemic strain of extensively drug-resistant tuberculosis (XDR-TB) - called LAM4/KZN- in KwaZulu-Natal, South Africa.

29 Oct 2019

Horrifying HIV epidemic in Pakistani town children due to syringe reuse

Allegations abound in this small Pakistani town of Ratodero, in the province of Sindh. Stung by poverty, pediatricians, barbers and dentists alike brave the risk of transmitting fatal and incurable HIV infection by sharing the same needles, tools and blades for multiple patients and clients, without sterilizing them in between uses.

28 Oct 2019

Researchers find antibody that may protect against wide range of lethal influenza viruses

A nationwide team of researchers has found an antibody that protects mice against a wide range of potentially lethal influenza viruses, advancing efforts to design of a universal vaccine that could either treat or protect people against all strains of the virus.

25 Oct 2019

TB is not a life-long infection in most people

A new analysis challenges the longstanding notion that tuberculous infection is a life-long infection that could strike at any time and cause tuberculosis. Based on a review of clinical studies, researchers from the Perelman School of Medicine at the University of Pennsylvania and colleagues show that people who test positive with immunologic TB skin or blood tests rarely develop TB.

25 Oct 2019

New analysis provides insight into dangerous conditions in U.S. immigrant detention centers

An analysis and related commentary published in Clinical Infectious Diseases today provide in-depth examination of the deplorable and dangerous conditions in U.S. immigrant detention centers where seven children have died in the last 10 months.

25 Oct 2019

Optimal implementation of existing, new interventions essential to end HIV pandemic

Optimal implementation of existing HIV prevention and treatment tools and continued development of new interventions are essential to ending the HIV pandemic, National Institutes of Health experts write in a commentary Clinical Infectious Diseases.

24 Oct 2019

ConvertibleCAR immunotherapy can be used to attack HIV latent reservoir

A team of Gladstone scientists and their partners at Xyphos Biosciences, Inc. describe a new way of attacking cells infected by HIV in this week's issue of the journal Cell.

24 Oct 2019

Wyss Institute joins Global Virus Network as new Center of Excellence to fight viral threats

Today, the Global Virus Network, a conglomerate of 52 "Centers of Excellence" and 9 Affiliates in 32 countries, which catalyzes collaborative research into diseases caused by every class of virus in humans and animals, announced the Wyss Institute for Biologically Inspired Engineering at Harvard University as a new Center of Excellence.

24 Oct 2019

UAB researchers awarded grant to study a vaccine for gonorrhea

University of Alabama at Birmingham researchers have been awarded a three-year contract with a total potential amount of $10 million to study the efficacy of the vaccine Bexsero - already licensed to prevent meningitis - in protecting vulnerable populations from infection with the bacteria that causes gonorrhea.

23 Oct 2019

New collaboration aims to develop gene-based cures for sickle cell disease and HIV

The National Institutes of Health plans to invest at least $100 million over the next four years toward an audacious goal: develop affordable, gene-based cures for sickle cell disease and HIV.

23 Oct 2019

New $30M contract signed to accelerate TB vaccine development across the country

Tuberculosis (TB) is the number-one cause of death from an infectious disease in the world: In 2017, the most recent data available, 10 million people developed TB and 1.6 million died.

23 Oct 2019

Anti-arthritis drug can stop tuberculosis bacillus from infecting blood stem cells

Immunologist Johan Van Weyenbergh (KU Leuven) and his Belgian-Brazilian colleagues have shown that a drug used to fight arthritis also stops the process that allows the tuberculosis bacillus to infect and hijack blood stem cells.

23 Oct 2019

New CRISPR genome “prime editing” system

Gene editing to correct genetic faults and removing the risk of hereditary diseases may soon become reality. Researchers have come up with a new gene editing technology that could help patients with sickle cell anaemia and up 89 percent of other genetic defects.

22 Oct 2019

Researchers assess accuracy of lateral flow urine LAM test in detecting TB in HIV-positive people

Tuberculosis (TB) causes more deaths in people living with HIV than any other disease, with more than 300,000 deaths in 2017. When detected, early TB can be treated effectively; however, people with advanced HIV are at high risk of death, often without knowing they have TB.

22 Oct 2019

TB care reaches 7 million says WHO report

The World Health Organization (WHO) has released a report on the latest status of treatment of tuberculosis worldwide. The report shows that around the world more people are getting adequate care for tuberculosis in 2018 than ever before but some vulnerable populations are still left out.

21 Oct 2019

Researchers identify new TB enzyme target to help fight deadly infection

Researchers have found a crucial enzyme in tuberculosis (TB) to target, allowing the development of new treatments to help fight against the disease's drug resistance.

18 Oct 2019

Research suggests nontraditional approach can improve outcomes for 'high-need, high-cost' patients

In crisis and with nowhere else to turn, thousands of patients with complex needs -- serious mental and physical health problems and substance use disorders -- every year flock to emergency rooms in Harris County, Texas and across the country.

17 Oct 2019

Temple researchers win NIH grant to study HIV-related neuroinflammation in context of opioid addiction

The National Institutes of Health has awarded a Temple research team a 5-year, $3.27 million grant to study neuroinflammation following HIV-infection in the context of opioid addiction.

16 Oct 2019

Syphilis rates in patients with kidney failure found to be greater than general population

Syphilis rates, like other sexually transmitted disease rates in the United States, are soaring, and the first known study to examine syphilis rates in patients with kidney failure found an incidence greater than three times that of the general population.

16 Oct 2019

HIV 1 News and Research

New TB vaccine: mid-phase trials confirm safety, long-term prevention

Study uses whole-genome sequencing for early identification and containment of AMR pathogens

Horrifying HIV epidemic in Pakistani town children due to syringe reuse

Researchers find antibody that may protect against wide range of lethal influenza viruses

TB is not a life-long infection in most people

New analysis provides insight into dangerous conditions in U.S. immigrant detention centers

Optimal implementation of existing, new interventions essential to end HIV pandemic

ConvertibleCAR immunotherapy can be used to attack HIV latent reservoir

Wyss Institute joins Global Virus Network as new Center of Excellence to fight viral threats

UAB researchers awarded grant to study a vaccine for gonorrhea

New collaboration aims to develop gene-based cures for sickle cell disease and HIV

New $30M contract signed to accelerate TB vaccine development across the country

Anti-arthritis drug can stop tuberculosis bacillus from infecting blood stem cells

New CRISPR genome “prime editing” system

Researchers assess accuracy of lateral flow urine LAM test in detecting TB in HIV-positive people

TB care reaches 7 million says WHO report

Researchers identify new TB enzyme target to help fight deadly infection

Research suggests nontraditional approach can improve outcomes for 'high-need, high-cost' patients

Temple researchers win NIH grant to study HIV-related neuroinflammation in context of opioid addiction

Syphilis rates in patients with kidney failure found to be greater than general population

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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