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HIV-infected patients three times more likely to suffer strokes

While the overall hospitalization rate for stroke has declined in recent years, the numbers have jumped dramatically for patients infected with human immunodeficiency virus (HIV), suggesting they may be up to three times more likely to suffer a stroke than people uninfected by the virus that causes AIDS.

20 Jan 2011

BI refuses to offer increased access to AIDS drugs for low-income Americans

AHF issued the following: Despite a growing national AIDS drug crisis, pharmaceutical giant Boehringer Ingelheim Pharmaceuticals, has steadfastly refused to offer increased access to its lifesaving AIDS drugs or to respond in any way to repeated requests by AIDS Healthcare Foundation, the largest global AIDS organization, to do its part in creating a solution.

20 Jan 2011

Koronis' KP-1461 drug causes extra mutations to occur in HIV genome in HIV-infected patients

Recently published Phase 2a clinical trial results show that the frequency of specific, drug-induced mutations in the HIV genome can be significantly increased by administering KP-1461, a drug being developed by Koronis Pharmaceuticals based on its novel Viral Decay Acceleration (VDA) drug mechanism.

20 Jan 2011

Swiss HIV Cohort Study identifies simple method to determine time of infection

Identifying the time of HIV infection. Researchers of the Swiss HIV Cohort Study have identified a simple method to establish when a patient contracted the virus causing . The time of infection can be of importance for the treatment of the illness and it contributes to the understanding of the course of the epidemic.

20 Jan 2011

UMB enters license agreement with Bali BioSciences for new strategy to combat sepsis, HIV/AIDS

The University of Maryland, Baltimore's (UMB) Office of Technology Transfer has completed a license agreement with Bali BioSciences LLC, an early-stage company pursuing an unusual, yet clever, strategy to combat disease.

20 Jan 2011

New research: HIV individuals are more likely to have stroke

New research suggests that people infected with human immunodeficiency virus may be up to three times more likely to have a stroke compared to those not affected with HIV. The study is published in the January 19, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

20 Jan 2011

Small molecules may inhibit entry of Ebola into human cells

Ebola, a virus that causes deadly hemorrhagic fever in humans, has no known cure or vaccine. But a new study by University of Illinois at Chicago scientists has uncovered a family of small molecules which appear to bind to the virus's outer protein coat and may inhibit its entry into human cells.

20 Jan 2011

Study: HIV-positive head and neck cancer patients respond well to radiation therapy treatments

HIV-positive head and neck cancer patients respond well to radiation therapy treatments and experience similar toxicity rates as non-HIV-positive patients, despite prior reports to the contrary, according to a study in the January issue of the International Journal of Radiation Oncology•Biology•Physics, an official journal of the American Society for Radiation Oncology.

19 Jan 2011

Scientists determine protein structure that delivers genetic material of HIV to human cells

A team of scientists at The Scripps Research Institute and the University of Virginia has determined the structure of the protein package that delivers the genetic material of the human immunodeficiency virus to human cells.

19 Jan 2011

Theraclone, Pfizer enter multi-year research and development collaboration

Theraclone Sciences, Inc., a therapeutic antibody discovery and development company, announced today that they have entered into a multi-year research and development collaboration with Pfizer. The collaboration will use Theraclone's I-STAR™ technology to discover broadly protective monoclonal antibodies against up to four undisclosed targets in the areas of infectious disease and cancer.

19 Jan 2011

Race and region play major role in health outcomes of people infected with HIV

Women, nonwhites, and people in the southern United States who were newly infected with HIV and followed for an average of four years experienced greater HIV/AIDS-related morbidity compared to men and people of other races living in other regions of the country. The findings, published in the February 15 issue of The Journal of Infectious Diseases, underscore the urgent need to improve the health of these populations in order to reduce HIV-related morbidity and mortality in the U.S.

19 Jan 2011

Transplant surgeons routinely use fewer organs from high-risk donors

As a response to a 2007 episode in which four patients in Chicago were transplanted with organs from a single donor unknowingly infected with HIV — the only such episode in 20 years — one-third of transplant surgeons in the United States "overreacted" and began routinely using fewer organs from high-risk donors, new research from Johns Hopkins finds.

19 Jan 2011

Researchers create biyouyanagin compound library

Using chemical compounds found in a Japanese plant as a lead and the clever application of ultraviolet light, a Scripps Research Institute team has created a unique library of dozens of synthetic compounds to test for biomedical potential. Already, one of the compounds has shown great promise in inhibiting replication of HIV particles and fighting inflammation.

19 Jan 2011

WHO Director-General opens executive board session with calls for reform

Kicking off a nine-day annual WHO executive board meeting Monday, WHO Director-General Margaret Chan called for the board to consider areas where the agency can redirect resources in a more targeted manner so as to achieve greater outcomes, Reuters reports.

19 Jan 2011

AMBR sensor measures growth and drug susceptibility of bacterial cells without use of microscope

With an invention that can be made from some of the same parts used in CD players, University of Michigan researchers have developed a way to measure the growth and drug susceptibility of individual bacterial cells without the use of a microscope.

19 Jan 2011

Research provides new insight into how HIV protein's structural changes may alter viral infection into healthy cells

The UK's National Physical Laboratory with the University of Edinburgh and IBM's TJ Watson Research Center have published new research about the structure of an HIV-1 protein that could help to develop new drugs to stop the virus infecting healthy cells.

19 Jan 2011

Guardian online series explores global health worker issues

The Guardian reports, as part of an online feature about health care workforces worldwide done in association with the Global Health Workforce Alliance (GHWA), that "Africa is desperately short of doctors and nurses. So is much of Asia. In 57 countries, the situation is deemed by the World Health Organisation (WHO) to be at crisis point ... But in contrast to some other developing world problems, this is an issue that really does affect all of us. The world needs an estimated 4.2 million more health workers."

19 Jan 2011

New York Times examines Russia's 'inadequate fight' against HIV/AIDS

Russia's HIV/AIDS epidemic "has defied worldwide trends, expanding more rapidly year by year than almost anywhere else," the New York Times writes in an article that examines how the country has become "one of the world's low points in the effort to fight the spread of HIV," in large part due to the government's failure to reach out to injecting drug users (IDUs) and sex workers - the groups "at the heart" of the epidemic.

18 Jan 2011

Harbor Biosciences signs development agreements for HE2000, HE3235 and HE3286 with CIPI

Harbor BioSciences, Inc., a leader in the development of a proprietary class of adrenal steroid hormones as novel pharmaceuticals, announced it has licensed the research and development and commercialization rights for three of its products, exclusively in the People's Republic of China and Hong Kong, to China State Institute of Pharmaceutical Industry (CIPI).

18 Jan 2011

Media look at what's ahead for South Sudan

"This week's independence referendum in southern Sudan marks an apparent victory for U.S. foreign policy in east Africa - one that has secured for Washington a deeper advisory role in what is expected to be the birth of a new, impoverished nation," according to a Wall Street Journal article looking at the issues facing the U.S. in south Sudan after voting concludes.

18 Jan 2011