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Molecular disruption of hypothalamic nutrient sensing induces obesity

In their latest finding on the brain's role in controlling appetite and weight, researchers at the Albert Einstein College of Medicine have shown that reducing levels of fatty acids in the hypothalamus causes rats to overeat and become obese. Their results suggest that restoring fatty-acid levels in the brain may be a promising way to treat obesity.

16 Jan 2006

Scientists design a fluorescent sensor capable of measuring intracellular acidity

The colouring agents traditionally used to stain organic tissues are no longer sufficient to meet today’s needs. The study of cell metabolism can only advance with better tools than those currently available.

16 Jan 2006

Identification of gene in childhood kidney disease

An international research collaboration led by Mayo Clinic has identified a new gene involved in causing the inherited kidney disorder, Meckel-Gruber syndrome (MKS). Children with MKS have central nervous system deformities as well as abnormal cysts in their kidneys, and usually die shortly after birth.

16 Jan 2006

Diabetes gene found in 40% of population

Researchers in Iceland say they have identified a single genetic change which could predispose close to 40 percent of the population to type-2 diabetes.

16 Jan 2006

Sickle cell corrected with gene copy

Scientists in the U.S. say they have found a way to use embryonic stem cells to correct the mutation that causes sickle cell disease in mice.

16 Jan 2006

St. Jude projects 90 percent cure rate for acute lymphoblastic leukemia

The cure rate for the once almost universally fatal childhood cancer acute lymphoblastic leukemia (ALL) could reach 90 percent in the near future, thanks to improvements in diagnosis and treatment over the past four decades, according to investigators at St. Jude Children's Research Hospital.

11 Jan 2006

Inhaled corticosteroids most effective for persistent asthma in children

While both inhaled corticosteroids (ICS) and leukotriene receptor antagonists (LTRA) have been proven to help control mild-to-moderate persistent asthma in school-age children, a new study shows ICS may be the more effective treatment.

11 Jan 2006

Vaccine candidate for hepatitis C

Researchers at the University of Saskatchewan's Vaccine and Infectious Disease Organization (VIDO) have developed a vaccine candidate for hepatitis C, leading to hope in the fight against a disease for which no vaccines are yet available.

11 Jan 2006

Lives will be saved as early signs of meningitis now identified

Scientists in the UK say they have identified the early signs of meningitis and blood poisoning which should improve detection of the disease and save lives.

11 Jan 2006

Obesity in middle age raises heart disease and diabetes risk

Obesity in middle age - even without established cardiovascular disease risk factors such as high blood pressure or high cholesterol levels - greatly increases risk of hospitalization for and death from heart disease and diabetes in older age, according to a study in the Jan. 11 issue of the JAMA: Journal of the American Medical Association.

10 Jan 2006

Brain plays a major role in the ability of insulin therapy to lower blood sugar in animals with diabetes

"Our findings suggest that, in individuals with diabetes, the ability of insulin to lower blood sugar involves the brain," said senior author of the study, Michael Schwartz of the University of Washington at Seattle. "This effect is not trivial; the brain makes a substantial contribution to insulin response."

10 Jan 2006

Anthroposophic lifestyle reduces the risk of allergic disease in children

Certain features of the anthroposophic lifestyle, such as restrictive use of antibiotics and fever antipyretics, reduce the risk of allergic disease in children, according to a new study.

10 Jan 2006

Carbohydrates improve insulin control

It is commonly believed that carbohydrates, particularly sugar, are a cause of insulin resistance and type 2 diabetes. However, such thinking has been challenged following the publication of a thorough appraisal of the evidence, in the latest edition of Nutrition Research Reviews.

10 Jan 2006

Limitless applications for nitric oxide in healthcare, bio-security, agriculture and industrial applications

Low levels of nitric oxide gas can prevent and kill disease-causing bacteria by tricking them into thinking their time is up, according to scientists from the Environmental Biotechnology Cooperative Research Centre (EBCRC) and the University of New South Wales.

10 Jan 2006

Erectile dysfunction may be sign of coming heart disease

Most wives would say their husbands are notoriously bad about avoiding the doctor’s office. Erectile dysfunction (ED) might be the only problem that prompts some men to go to a physician. According to a new study, it could be their best chance at finding out they have underlying cardiovascular disease.

10 Jan 2006