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Benefits of MAO-B inhibitors are small but may be worthwhile in some patients with early Parkinson's disease

A class of drugs known as MAO-B inhibitors may be effective in improving motor symptoms in people with early Parkinson's disease and may delay the need for treatment with other drugs, according to a new systematic review of current evidence.

23 Aug 2005

Study examines the incidence and risk factors associated with Hepatitis C infection in rural Egypt

The prevalence of antibodies to Hepatitis C Virus (HCV) in Egypt is among the highest in the world. From the 1950s until 1982 hundreds of thousands were infected during mass campaigns to control schistosomiasis (a parasitic disease) using mass therapy with intravenous antimony compounds, but little is known about current risk factors and rates of transmission.

23 Aug 2005

Dietary supplement chitosan shows some promise in treating obesity

The dietary supplement chitosan shows some promise in treating overweight and obesity but has not been shown conclusively to be an effective weight loss aid, according to a new systematic review of current evidence.

23 Aug 2005

Study shows potential treatment for brain cancer

A compound that kills cancer can sneak past the blood brain barrier, which protects the brain from foreign substances, to do its work in fighting a particularly invasive brain cancer, according to a new Saint Louis University animal study published in the Proceedings of the National Academy of Sciences Online Early Edition the week of Aug. 22.

22 Aug 2005

MRI helps map smallest deformations inside hearts

Using magnetic resonance imaging technology, or MRI, to tag the work of millions of individual strands of heart muscle fibers, researchers at Johns Hopkins have successfully mapped the smallest deformations inside the beating hearts of 441 middle-aged and elderly men and women who have either silently developed heart disease or remained healthy.

22 Aug 2005

Gene therapy advance shows potential for developing improved treatment for hemophilia

A virus that typically infects insects could help with the development of gene therapy treatment for Hemophilia A, a condition in which even a bump on the knee can cause serious internal bleeding in people.

22 Aug 2005

Heart healthy habits are good for oral health

Heart healthy habits are good for oral health, too, according to a new study published in the current issue of the Journal of Periodontology, the official publication of the American Academy of Periodontology.

22 Aug 2005

Experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma

Researchers at The University of Texas M. D. Anderson Cancer Center and the National Cancer Institute have found that an experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma, even though prior therapy had eliminated virtually all of the B cells thought necessary to mount such a defense.

22 Aug 2005

Health benefits of different types of language use and writing contexts now explored

Researchers have known for some time that expressive writing can have a positive effect on the writer's health, such as illness recovery.

22 Aug 2005

Researchers test experimental drug Neuprex on infants undergoing heart surgery

UT Southwestern Medical Center is the only institution in the nation approved by the Food and Drug Administration to test an experimental drug on infants undergoing heart surgery to see whether it can help them avoid potentially lethal infections and improve survival.

22 Aug 2005

Stockings which provide an alternative to physiotherapy

A team of researchers at Imperial College London have developed inflatable stockings to give relief to elderly people with mobility problems.

22 Aug 2005

Non-invasive imaging may help predict type 1 diabetes and response to treatment in humans

A key obstacle to early detection of type 1 diabetes - as well as to rapid assessment of the effectiveness of therapeutic intervention - has been the lack of direct, non-invasive technologies to visualize inflammation in the pancreas, an early manifestation of disease.

22 Aug 2005

First proof of how the rare disorder Fanconi anemia causes chromosomal instability

The scientists found a gene mutation not previously known to be related to Fanconi anemia, and they say that BRIP1 is the first gene associated with the disease whose protein has a known function.

22 Aug 2005

Enzyme in the blood that could be a potential marker for heart failure

A team of scientists led by Walter Koch, Ph.D., director of the Center for Translational Medicine in the Department of Medicine in Jefferson Medical College of Thomas Jefferson University in Philadelphia, previously showed that an enzyme called GRK2 or beta-adrenergic kinase (ßARK1) is critically important in heart function.

22 Aug 2005

Increasing sugar processing in the liver may lead to future treatments for diabetes, obesity

Researchers at the University of Minnesota have shown that increasing the concentration of a key regulator involved in glucose metabolism can improve the way the liver produces and disposes of the sugar glucose, the primary fuel of the body. Finding ways to increase that concentration could provide a treatment for diabetes and obesity.

22 Aug 2005

New guidelines to battle heart failure

Early diagnosis and new treatments can help battle heart failure -- a growing national problem that causes 1 million hospital admissions each year, according to new guidelines released by the American College of Cardiology (ACC) and the American Heart Association (AHA).

22 Aug 2005

SH2-B enhances brain's leptin sensitivity - may lead to clues for treatment of obesity and diabetes

What do laboratory mice at the University of Michigan Medical School have in common with millions of overweight Americans? Like many of us, these mice just can't stop eating.

18 Aug 2005

Protein Sirt1 points to new therapies for type 2 diabetes

Opening the possibility of new therapies for type 2 diabetes, researchers at Washington University School of Medicine in St. Louis have found that a protein called Sirt1 enhances the secretion of insulin in mice and allows them to better control blood glucose levels. Their study appears in the August 17 issue of Cell Metabolism.

18 Aug 2005

Reasons for complications with kidney failure patients

Mayo Clinic researchers searching for explanations of high mortality rates among kidney failure patients undergoing hemodialysis are focusing their attention on the use of heparin, a drug used to reduce clotting of the blood.

18 Aug 2005

Slower care for heart attack patients treated after hours and on weekends

Heart attack patients treated with primary percutaneous intervention (PCI) at hospitals after hours and on weekends wait longer to receive clot busters and other treatments and have a higher risk of death than those treated during regular hospital hours

18 Aug 2005

Blood News and Research

Benefits of MAO-B inhibitors are small but may be worthwhile in some patients with early Parkinson's disease

Study examines the incidence and risk factors associated with Hepatitis C infection in rural Egypt

Dietary supplement chitosan shows some promise in treating obesity

Study shows potential treatment for brain cancer

MRI helps map smallest deformations inside hearts

Gene therapy advance shows potential for developing improved treatment for hemophilia

Heart healthy habits are good for oral health

Experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma

Health benefits of different types of language use and writing contexts now explored

Researchers test experimental drug Neuprex on infants undergoing heart surgery

Stockings which provide an alternative to physiotherapy

Non-invasive imaging may help predict type 1 diabetes and response to treatment in humans

First proof of how the rare disorder Fanconi anemia causes chromosomal instability

Enzyme in the blood that could be a potential marker for heart failure

Increasing sugar processing in the liver may lead to future treatments for diabetes, obesity

New guidelines to battle heart failure

SH2-B enhances brain's leptin sensitivity - may lead to clues for treatment of obesity and diabetes

Protein Sirt1 points to new therapies for type 2 diabetes

Reasons for complications with kidney failure patients

Slower care for heart attack patients treated after hours and on weekends

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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