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Two out of three Americans with type-2 diabetes do not have their disease under control

According to a new survey two out of three Americans with type-2 diabetes do not have their disease under control and are putting themselves at risk of early deaths from stroke, heart attack or kidney failure as well as blindness and limb loss.

18 May 2005

Patients with type 2 diabetes who participate in group education programs require less medication

Group-based education resulted in improved diabetes control as reflected by blood glucose levels and patients’ knowledge of diabetes. Evidence also suggested that participants in diabetes group education programs may reduce their blood pressure and body weight and increase self-empowerment, quality of life, self-management skills and treatment satisfaction.

18 May 2005

Hydroxycitric acid slows glucose uptake, cuts insulin peaks

In this obesity-obsessed world, the dream ingredient must be something that tastes good enough to be a condiment or flavoring and yet somehow helps us keep our weight down. Consider hydroxycitric acid (HCA), known variously as Brindle berry or Malabar tamarind, which is used in Indian and Thai food as a condiment and flavoring agent.

18 May 2005

Global project to combat parasites that cause cancer and infection in millions

Many cancers are associated with infections (for example cervical cancer is linked to the human papilloma virus) but there is no stronger link between a human malignancy and a parasitic infection than that between cancer of the bile ducts and a liver fluke called Opisthorchis viverrini.

18 May 2005

Nutritional composition of a mother’s breast milk may depend not just on her diet - but on her genes

“It is well known that genes control the nutrient levels in cow’s milk” said Richard B. Weinberg, M.D. “But until now, no one has considered how genes might affect human breast milk. This is the first study to demonstrate a genetic effect on human lactation.” The results were presented today at Digestive Disease Week 2005 in Chicago, Ill.

18 May 2005

Advanced breast cancer drug appears effective on multiple targets

An experimental breast cancer drug that simultaneously attacks five tumor targets has halted progression of the disease in a clinical trial for patients with advanced disease.

18 May 2005

Roche to discontinue the sale and distribution of Fortovase (saquinavir)

Roche announced today that it has decided to discontinue the sale and distribution of Fortovase (saquinavir), as clinical demand for the drug has declined significantly due to the availability of a new formulation of Invirase (saquinavir mesylate), which increasingly has become the preferred formulation of saquinavir.

18 May 2005

Cardiovascular risk factors among homeless people are under-treated in Canada

The study, the first comprehensive assessment of cardiovascular risk factors in a representative sample of homeless adults, also found that cardiovascular risks among the homeless may be underestimated due to commonly used risk assessment tools that do not account for cocaine use and the level of smoking exposure.

18 May 2005

Scientists confirm rarefied air poses in-flight problem

More than half of all air passengers experience significant blood oxygen decreases at high altitudes, UK researchers report in the scientific journal Anaesthesia. We take a look at the findings and EU research in the aeronautics field.

18 May 2005

Hypertension drug combination yields high rate of blood pressure control in hard-to-treat patients

The study, conducted at the University of Maryland School of Medicine and 118 other sites, was focused on bringing down systolic blood pressure, the top number in a blood pressure reading, which is the more difficult number to bring down.

18 May 2005

Telemonitoring or telephone calls prevent heart failure deaths

Monitoring heart failure patients with either high-tech home monitors or through regular telephone contacts with nurses improves the odds they will survive during the months after a serious hospitalization, according to a new study in the May 17, 2005, issue of the Journal of the American College of Cardiology.

18 May 2005

Routine, inexpensive blood test sharpens heart disease risk predictions

Routine measurements of white blood cell counts that provide a ratio of neutrophils to lymphocytes may offer a simple and low-cost way to refine predictions of heart attack or death, according to a new study in the May 17, 2005, issue of the Journal of the American College of Cardiology.

18 May 2005

A drug that controls blood pressure and reduces heart risk also appears to protect against diabetes

In new results from the VALUE trial that pitted the drug valsartan against another blood pressure drug, amlodipine, the patients taking valsartan were found to have a 23 percent lower risk of developing diabetes during the four or more years of the study.

18 May 2005

New blood tests for both prostate and colon cancer

Tessera Inc., a Seattle-based biomedical company is, in collaboration with Dr. Robert Getzenberg, Director of the Brady Urological Research Institute at Johns Hopkins University, developing blood tests for both prostate and colon cancer and expects to commence clinical trials on EPCA (Early Prostate Cancer Antigen), its first blood test for prostate cancer, before the end of this year.

18 May 2005

Don’t skip chest CT in the ER just because X-ray checks out okay, warns study

Chest X-rays may miss 40% of clinically significant thoracic injuries in multiple trauma patients that can be caught by chest CT, say researchers from Massachusetts General Hospital in Boston.

18 May 2005

Chronic stress can be harmful - to your health and also to your brain

Chronic stress can be harmful - to your health and also to your brain, according to researchers at the Douglas Hospital Research Center. Their findings, published in a recent issue of Psychoneuroendocrinology, show increased stress hormones lead to memory impairment in the elderly and learning difficulties in young adults.

17 May 2005

Zevalin safe and effective for non-Hogdkin's lymphoma patients

According to a University of Pittsburgh Medical Center (UPMC) study, patients with advanced non-Hodgkin's lymphoma (NHL) previously treated with chemotherapy and adult stem cell transplantation can safely tolerate Zevalin (ibritumomab tiuxetan), a radiolabeled monoclonal antibody that targets radiation directly to a tumor.

17 May 2005

Breast cancer chemotherapy regimen associated with life-threatening complications

The chemotherapy regimen of doxorubicin plus docetaxel, used to treat breast cancer in a clinical trial, was associated with an increased risk of serious complications, resulting in the premature termination of the trial, according to a study in the May 18 issue of JAMA.

17 May 2005

Patients who have a blood clot are at high risk of having another one, and men have more than twice the risk as women

While estimates of the overall risk of a thrombotic (blood clot) event recurrence vary, reports on contributing factors are contradictory, according to background information in the article. Knowledge of the risk of a thrombotic event recurrence and its determinants is relevant for clinical policy regarding screening for thrombophilia (increased risk for blood clot), duration of anticoagulant treatment, and treatment strategies in circumstances of increased risk.

17 May 2005

Tumor vasculature has become an attractive target in the treatment of cancer.

Treatment with a protein fused to an antibody in tumor-bearing mice led to coagulation of the blood within the tumor blood vessels, tumor tissue death, and tumor growth delay, according to a new study in the May 18 issue of the Journal of the National Cancer Institute.

17 May 2005