Birth Defects News and Research

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Imaging studies required to diagnose traumatic injuries in pregnant women can be safe when used properly

According to a new study in the Journal of the American Academy of Orthopaedic Surgeons (JAAOS), imaging studies necessary to diagnose traumatic injuries sustained by pregnant women are safe when used properly.

7 Aug 2015

Radiation from solar events too weak to cause birth defects down on Earth's surface

Studies find airplane crews at high altitude are exposed to potentially harmful levels of radiation from cosmic rays.

29 Jul 2015

Novartis announces FDA approval of Odomzo (sonidegib) 200 mg capsules for treatment of laBCC patients

Novartis today announced the US Food and Drug Administration has approved Odomzo (sonidegib, formerly LDE225) 200 mg capsules for the treatment of adult patients with locally advanced basal cell carcinoma (laBCC) that has recurred following surgery or radiation therapy, or those who are not candidates for surgery or radiation therapy.

25 Jul 2015

Alternative limb-lengthening technique makes recovery process less cumbersome

A highly specialized procedure that lengthens bones can prevent the need for amputations in selected patients who have suffered severe fractures.

20 Jul 2015

Mylan announces launch of Bexarotene 75mg Capsules in U.S.

Mylan N.V. today announced the U.S. launch of Bexarotene 75mg Capsules, which is the generic version of Valeant's Targretin Capsules. This product is indicated for the treatment of cutaneous manifestations of cutaneous t-cell lymphoma in patients who are refractory to at least one prior systemic therapy.

9 Jul 2015

Women who take stop-smoking drug Zyban during pregnancy give birth to a child with birth defects

The Arentz Law Group is currently investigating cases of birth defects caused by the stop-smoking drug Zyban. Women who have taken Zyban while pregnant, and given birth to a child born with a birth defect, are encouraged to contact the law firm immediately for a free legal consultation.

7 Jul 2015

University of Georgia's Lynn Bailey leads international paper on folate biomarkers

A University of Georgia researcher is lead author on an international paper on folate biomarkers as part of an initiative to provide evidence-based guidance for the global nutrition and public health community.

1 Jul 2015

UT Southwestern researchers identify two proteins within fetal lungs that initiate labor process

Researchers at UT Southwestern Medical Center have identified two proteins in a fetus' lungs responsible for initiating the labor process, providing potential new targets for preventing preterm birth.

23 Jun 2015

Cosmetic surgery could improve lives of people with facial paralysis

A cosmetic surgery that uses injections of hyaluronic acid to make lips appear fuller could also improve the lives of people with facial paralysis, according to results of a small study by researchers at Johns Hopkins and Stanford universities.

19 Jun 2015

Study on how maternal proteins help regulate initial cell divisions during early development

Researchers in the University of Georgia's Regenerative Bioscience Center are visually capturing the first process of chromosome alignment and separation at the beginning of mouse development. The findings could lead to answers to questions concerning the mechanisms leading to birth defects and chromosome instability in cancer cells.

10 Jun 2015

Upsher-Smith announces FDA approval of sNDA for Qudexy XR extended-release capsules

Upsher-Smith Laboratories, Inc. announced that it has received U.S. Food and Drug Administration approval of a supplemental new drug application (sNDA) for Qudexy XR (topiramate) extended-release capsules for use as initial monotherapy in patients two years of age and older who are experiencing partial-onset seizures (POS) or primary generalized tonic-clonic seizures.

2 Jun 2015

Pre-pregnancy maternal weight has significant impact on baby's immune system

Almost 60 percent of women of childbearing age in the United States are overweight or obese. Obesity is a major public health issue, and has been linked to health problems like heart disease, cancer and hypertension. It can complicate pregnancy by increasing the mother's risk of having gestational diabetes, preeclampsia, preterm birth or a baby with birth defects. Maternal obesity is also linked to several adverse health outcomes for the infant that can persist into adulthood, such as type-2 diabetes, heart disease and mortality.

19 May 2015

TGen-led study associates 'X-linked' syndromes to genetic origins

A study led by the Translational Genomics Research Institute has for the first time matched dozens of infantile diseases and syndromes involving muscle weakness and stiff joints to their likely genetic origins.

14 May 2015

Rudolf Jaenisch honored with 2015 March of Dimes Prize in Developmental Biology

Rudolf Jaenisch, MD, who laid the groundwork for the development and use of induced pluripotent stem (iPS) cells - stem cells derived directly from adult tissue -- to potentially treat and cure a variety of human diseases, has received the 20th anniversary March of Dimes Prize in Developmental Biology.

30 Apr 2015

Physical forces can affect development of limbs in embryos

University of Toronto engineers and a pediatric surgeon have joined forces to discover that physical forces like pressure and tension affect the development of limbs in embryos--research that could someday be used to help prevent birth defects.

23 Apr 2015

Upsher-Smith presents favorable data from PREVAIL OLE study of Qudexy XR capsules

Upsher-Smith Laboratories, Inc. presented data from a 52-week, open-label extension study (PREVAIL OLE) showing that Qudexy XR (topiramate) extended-release capsules offered a long-term adjunctive treatment option with a favorable tolerability profile for a high proportion of patients with refractory partial-onset seizures (POS).

21 Apr 2015

New CUMC study finds DNA anomalies in kids with chronic kidney disease

A significant proportion of children with chronic kidney disease (CKD) have unsuspected chromosomal imbalances, including DNA anomalies that have been linked to neurocognitive disorders, according to a new Columbia University Medical Center study.

21 Apr 2015

UofL-led study focuses on flu vaccine for children with neurological disorders

Children who have neurological disorders such as cerebral palsy or epilepsy are no more likely to be vaccinated against influenza than youngsters without these conditions, despite the increased risk for complications from flu these children experience.

10 Apr 2015

Amniotic stem cells promote growth of functional blood vessels in healing hydrogels

Rice University and Texas Children's Hospital scientists are using stem cells from amniotic fluid to promote the growth of robust, functional blood vessels in healing hydrogels.