Lipoprotein News and Research

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A lipoprotein is a biochemical assembly that contains both proteins and lipids. The lipids or their derivatives may be covalently or non-covalently bound to the proteins.

FDA authorizes marketing of PicoAMH Elisa test to help determine woman's menopausal status

Today, the U.S. Food and Drug Administration permitted marketing of the PicoAMH Elisa diagnostic test as an aid in the determination of a patient's menopausal status.

25 Oct 2018

Carnegie scientist awarded NIH grant to identify novel medicines for cardiovascular disease

Carnegie's Department of Embryology scientist Steven Farber and team have been awarded a 5-year $3.3-million NIH grant to identify novel pharmaceuticals for combatting a host of diseases associated with altered levels of lipoproteins like LDL ("bad cholesterol").

11 Oct 2018

Seed oils are best choice for improving cholesterol

If you want to lower your low-density lipoprotein cholesterol, called LDL or, colloquially, "bad cholesterol," the research is clear about one thing: You should exchange saturated fats with unsaturated fat. If you want to know what you should use to sauté your dinner, that's a harder question to answer. Many of the studies establishing that mono- and polyunsaturated fats are better for blood lipids than saturated fats swapped out one food source at a time, making it hard to tell which of a plethora of vegetable oils might be most beneficial.

9 Oct 2018

Study analyzes distribution of two cytokines in sections of carotid atherosclerotic plaques

Inflammation is currently a well-documented component of atheroslcerosis pathogenesis, which plays a role at each stage of the disease development.

6 Oct 2018

FARXIGA receives positive results in Phase III DECLARE-TIMI 58 cardiovascular outcomes trial

AstraZeneca today announced positive results from the Phase III DECLARE-TIMI 58 cardiovascular outcomes trial for FARXIGA, the broadest SGLT-2 inhibitor CVOT conducted to date.

24 Sep 2018

New review highlights nurses' role in helping reduce health risks of prolonged sedentary time

Sitting for too many hours per day, or sitting for long periods without a break, is now known to increase a wide range of health risks, even if one engages in recommended amounts of physical activity.

31 Aug 2018

New system that uses AI accurately detects patients with diabetic retinopathy

A system designed by a University of Iowa ophthalmologist that uses artificial intelligence to detect diabetic retinopathy without a person interpreting the results earned Food and Drug Administration authorization in April, following a clinical trial in primary care offices.

28 Aug 2018

Study shows new options to lower heart disease risk in people with diabetes

A drug used to manage diabetes may reduce heart disease and death in people with diabetes regardless of their cholesterol levels and whether they are on a statin therapy, suggests a new analysis of the LEADER trial.

27 Aug 2018

Very high levels of good cholesterol may increase risk of heart attack and death

Very high levels of high-density lipoprotein cholesterol may be associated with an increased risk of heart attack and death, according to research presented today at ESC Congress 2018.

25 Aug 2018

Standard hypothyroidism treatment inadequate in controlling crucial aspects of the condition

What if the standard treatment for hypothyroidism--insufficient thyroid hormone--is inadequate in controlling some crucial aspects of the condition? That's the provocative question asked, and answered affirmatively with objective data, in a study led by a Rush researcher presented this week in The Journal of Clinical Endocrinology & Metabolism.

22 Aug 2018

Elevated LDL cholesterol levels linked to higher risk of CVD death in young, healthy people

Young, healthy people may still face a lifetime risk of premature death from cardiovascular disease if they cannot keep their cholesterol levels in check, according to new observational research in the American Heart Association's journal Circulation.

20 Aug 2018

Protective qualities of 'good cholesterol' reduce after menopause

Levels of high density lipoprotein (HDL) may not accurately represent cardiovascular risk in older women, according to a new study.

19 Jul 2018

Research shows link between higher serum vitamin D levels and lower cholesterol in children

There is a link between higher serum vitamin D levels and lower plasma cholesterol levels in primary school children, new research from the University of Eastern Finland shows. Children whose serum 25-hydroxyvitamin D levels exceeded 80 nmol/l had lower plasma total and low-density lipoprotein cholesterol levels than children whose serum 25-hydroxyvitamin D levels were below 50 nmol/l, which is often regarded as a threshold value for vitamin D sufficiency

8 Jun 2018

Study: Tree nut consumption linked to improved type 2 diabetes health

One of the largest studies to date on nuts and diabetes was published today in Diabetologia, the journal of the European Association for the Study of Diabetes. The study shows that approximately two ounces of nuts a day, as a replacement for carbohydrate foods, can improve glycemic control and blood lipids in those with type 2 diabetes.

24 May 2018

PSCK9 inhibitors may provide benefit to atherosclerosis patients with high lipoprotein(a) levels

Lipoprotein(a) is a variant of LDL (low-density lipoprotein) cholesterol, and large amounts of data have shown that higher lipoprotein(a) levels are associated with an increased risk of cardiovascular events.

22 May 2018

Familial Chylomicronemia Syndrome: How HCP’s can Support Patients with Rare Diseases

Dr Robert Cramb gives an introduction to the rare disease FCS, and how HCP's can best advise and support patients with the condition.

15 May 2018

Study discovers genetic variations that increase heart attack risk for statin patients

A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol.

10 May 2018

New study aims to help clear up conflicting dietary advice around egg consumption

University of Sydney researchers aim to help clear up conflicting dietary advice around egg consumption, as a new study finds eating up to 12 eggs per week for a year did not increase cardiovascular risk factors in people with pre-diabetes and type 2 diabetes.

7 May 2018

Gene therapy offers potential cure for patients with lipoprotein lipase deficiency

During the first 18 months after treatment with ali-pogene tiparvovec, a gene therapy recently approved in Europe to treat lipoprotein lipase deficiency (LPLD), the first patient to receive the treatment had no abdominal pain or episodes of pancreatitis, following a history of 37 pancreatitis attacks.

2 May 2018

Vegetarian diet and Mediterranean diet close to each other in health benefits

At present, the Mediterranean diet is considered to be one of the healthiest diets that provide multiple benefits to the heart as well as aiding in losing weight.

23 Apr 2018