Antigen News and Research

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Updates on pandemic flu vaccine trials to be presented at 44th Annual IDSA meeting

Preliminary results from clinical trials testing two different pandemic flu vaccine approaches - one a prime-boost strategy using different subtypes of H5N1 vaccines, the other an H5N1 vaccine delivered into the skin (intradermal) rather than the muscle - will be presented at the 44th Annual Meeting of the Infectious Diseases Society of America.

16 Oct 2006

Lower PSA in obese men could be a warning

Researchers in the U.S. say that obese men have lower levels of a protein used to screen for prostate cancer risk, and doctors should take weight into account when determining a man's risk.

10 Oct 2006

Super chow, laced with semi-synthetic vitamin E derivative, inhibited spread of cancer in mice

A chemically altered form of vitamin E mixed into mouse chow dramatically reduced spread of aggressive mammary cancer in mice, suggesting that the compound in pill form could be used to treat human metastatic cancer, according to a report in the October 1 issue of the journal Cancer Research.

2 Oct 2006

Carbon nanotube amplification strategies for highly sensitive immunodetection of cancer biomarkers

In an attempt to increase the sensitivity of cancer biomarker detection and to decrease the need for large samples from which to detect those molecules, a multi-institutional research team has shown that a "forest" of single-walled carbon nanotubes can be used to detect lower levels of the prostate specific antigen (PSA) than is possible using the current commercial assay.

25 Sep 2006

M. D. Anderson targets asthma and allergic diseases

A new research alliance focuses on a molecular master switch suspected of igniting the inflammatory immune response that drives asthma and other allergic diseases.

20 Sep 2006

Cell detachment model for an antibody-based microfluidic cancer screening system

In the quest to detect more types of cancers at ever earlier stages, researchers have been stymied by a lack of cell surface markers that distinguish in a clear-cut manner between healthy and malignant cells.

19 Sep 2006

Study extends the number of antigenic peptides that can be produced from a single protein

Understanding medical research problems often relies on the direct, linear relationship between the sequence of a protein and the DNA encoding that protein. In fact, colinearity of DNA and protein sequences is thought to be a fundamental feature of the universal genetic code.

13 Sep 2006

Immunotherapy for heart failure

World Congress of Cardiology Report - Heart failure (HF) is a complex, progressive clinical syndrome that can result from any structural or functional cardiac disorder, such as coronary artery disease or hypertension (high blood pressure), which impairs the ability of the heart to function properly as a pump.

5 Sep 2006

Researchers identify genetic risk for type 1 diabetes

A discovery at the Barbara Davis Center for Childhood Diabetes has identified a genetic risk for type 1 diabetes three to four times higher than previously thought possible.

4 Sep 2006

Induction of potent antitumor immunity by intratumoral injection of IL-23 transduced dendritic cells

One therapy for treating brain tumors alerts the immune system to the presence of foreign material. A second therapy enhances the first and prolongs the immune system's response.

4 Sep 2006

Scientists create tumour zapping T cells which knock out cancer

Scientists in the United States have genetically engineered normal immune cells to become specialized fighters and used them to attack cancerous tumours.

31 Aug 2006

Aspirin may improve men's urinary health and prevent enlarged prostate

Researchers suggest that taking nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin or ibuprofen may improve men's urinary health.

31 Aug 2006

Morphotek granted two European technology patents

Morphotek has announced that the European Patent Office has given a "Decision of Grant" regarding the Company's US Patent 6,921,666 entitled "Methods for Generating Hypermutable Yeast" and US Patent 6,737,268 entitled "A Method for Generating Genetically Altered Antigens."

30 Aug 2006

Mayo clinic finds NSAIDs may prevent or delay enlarged prostate

Mayo Clinic researchers have found that taking nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin or ibuprofen may prevent or delay benign prostatic hyperplasia.

30 Aug 2006

Chinese scientists come up with safe and effective bird flu vaccine

According to official reports a bird flu vaccine for humans developed by Chinese researchers has proven to be both safe and effective.

29 Aug 2006

Women's health policy highlights

Highlights recently released from journal articles on women's health issues

24 Aug 2006

Iomai launches study of vaccine patch for travelers' diarrhea

Iomai Corporation has announced that it has begun enrollment of a Phase 2 trial designed to test its vaccine patch for travelers' diarrhea in volunteers traveling to sites in Mexico and Guatemala.

15 Aug 2006

Elite suppressors of HIV to change how scientists monitor spread of disease

Scientists at Johns Hopkins have found that 1 percent to 2 percent of those infected with HIV in Baltimore apparently suppress the virus to nearly undetectable levels on their own, confounding public health efforts to accurately monitor the pandemic's spread, now in its 20th year.

15 Aug 2006

Researchers find precise location where an antibody binds to the West Nile virus

Researchers have learned the precise location where an antibody binds to the West Nile virus, and they have suggested a mechanism for how this antibody neutralizes the virus to prevent infection.

14 Aug 2006

Discovery of mechanism that may explain post-transplant lymphoproliferative disorder

A serious form of cancer that occurs in some transplant patients may arise because cells that normally serve as scouts for the immune system become weakened, a new study suggests.

8 Aug 2006