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Avoidant grievers unconsciously monitor and block mind-wandering contents, study shows

People who are grieving a major loss, such as the death of a spouse or a child, use different coping mechanisms to carry on with their lives. Psychologists have been able to track different approaches, which can reflect different clinical outcomes.

11 Dec 2018

Novel 3D printing workflow helps predict leaky heart valves

More than one in eight people aged 75 and older in the United States develop moderate-to-severe blockage of the aortic valve in their hearts, usually caused by calcified deposits that build up on the valve's leaflets and prevent them from fully opening and closing.

11 Dec 2018

Ezogabine treatment reduces motor neuron excitability in ALS patients, study shows

Brian Wainger, MD, PhD, of the Healey Center for ALS at Massachusetts General Hospital presented initial, top-level results of a recently completed phase 2 clinical trial of ezogabine (also called retigabine) on December 9 at the Motor Neurone Disease Association annual meeting in Glasgow, Scotland.

11 Dec 2018

Episodic memory tests help in predicting brain atrophy and Alzheimer’s disease

Use of two episodic memory tests help in predicting brain atrophy and Alzheimer’s disease, as indicated by a study carried out at the University of Helsinki and the University of California. Researchers suggest that comprehensive use of memory tests could improve the diagnosis of mild cognitive impairment due to Alzheimer’s disease.

10 Dec 2018

Updated breast cancer screening guideline highlights importance of shared decision-making

An updated guideline on screening for breast cancer emphasizes shared decision-making between women and their doctors, supporting women to make an informed decision based on personal preferences when the balance between benefits and harms is uncertain.

10 Dec 2018

Researchers discover a 'blind spot' in atomic force microscopy

Researchers have discovered a 'blind spot' in atomic force microscopy - a powerful tool capable of measuring the force between two atoms, imaging the structure of individual cells and the motion of biomolecules.

10 Dec 2018

CZI announces funding for open-source software efforts to improve image analysis in biomedicine

Today, the Chan Zuckerberg Initiative announced funding for open-source software efforts to improve image analysis and visualization in biomedicine. Microscopy -- critical to modern cell biology -- generates large volumes of complex data that pose significant challenges for analysis and visualization.

7 Dec 2018

New diagnostic tools may help identify breast cancer patients who could benefit from targeted therapies

A set of emerging diagnostic tools may help identify breast cancer patients who are most likely to benefit from therapies that target important enzymes fueling a range of subtypes, including BCRA-mutated and triple negative cancers.

7 Dec 2018

Researchers use new methods to optimize treatments for tuberculosis meningitis

Although relatively rare in the United States, and accounting for fewer than 5 percent of tuberculosis cases worldwide, TB of the brain--or tuberculosis meningitis (TBM)--is often deadly, always hard to treat, and a particular threat to young children.

6 Dec 2018

Study sheds new light on microtubule binding proteins and microtubule dynamics

When bacteria or viruses enter the body, proteins on their surfaces are recognized and processed to activate T cells, white blood cells with critical roles in fighting infections.

6 Dec 2018

Researchers are developing blood test to diagnose or predict Alzheimer's disease

Today, the only way to definitively diagnose Alzheimer's disease in life is through brain scans and tests of cerebrospinal fluid that must be collected via lumbar puncture. Though cumbersome and expensive, such tests provide the most accurate diagnoses for patients.

6 Dec 2018

Individual neurons located within the brain have implications for psychiatric diseases

Everyone makes little everyday mistakes out of habit--a waiter says, "Enjoy your meal," and you respond with, "You, too!" before realizing that the person is not, in fact, going to be enjoying your meal.

6 Dec 2018

Researchers develop biosensors to detect and measure metastatic potential of cancer cells

The spread of invasive cancer cells from a tumor's original site to distant parts of the body is known as metastasis. It is the leading cause of death in people with cancer. In a paper published online in iScience, University of California San Diego School of Medicine researchers reported engineering sensors that can detect and measure the metastatic potential of single cancer cells.

6 Dec 2018

Functional ultrasound imaging can reveal brain activity maps of mice for specific behaviors

In a study published in Neuron, Emilie Macé from Botond Roska's group and collaborators demonstrate how functional ultrasound imaging can yield high-resolution, brain-wide activity maps of mice for specific behaviors.

5 Dec 2018

Cancer patients who take beta-blocker along with breast cancer drug have less heart damage

Breast cancer patients who take a heart drug at the same time as trastuzumab have less heart damage, according to a study presented today at EuroEcho-Imaging 2018.

5 Dec 2018

NIH-funded tissue chips that model aspects of the human immune system sent to space

When traveling in space, astronauts experience physiological changes normally associated with aging, such as bone loss, muscle deterioration and altered immune systems. When the astronauts return to Earth, the changes often reverse.

5 Dec 2018

CEASE intervention enhances delivery of smoking cessation assistance for breastfeeding mothers

A study led by MassGeneral Hospital for Children researchers demonstrates that an MGHfC-developed program designed to help the parents of pediatric patients quit smoking can increase the provision of such assistance to breastfeeding mothers.

5 Dec 2018

New discovery offers parameter for predicting progression of oral cancer

Researchers in Brazil have identified a correlation between oral cancer progression and the abundance of certain proteins present in tumor tissue and saliva.

5 Dec 2018

New study supports use of ZnO nanoparticles in sunscreens

Zinc oxide has long been recognized as an effective sunscreen agent. However, there have been calls for sunscreens containing ZnO nanoparticles to be banned because of potential toxicity and the need for caution in the absence of safety data in humans.

4 Dec 2018

Yale researchers predict how people's eyes move when viewing natural scenes

Using precise brain measurements, Yale researchers predicted how people's eyes move when viewing natural scenes, an advance in understanding the human visual system that can improve a host of artificial intelligence efforts, such as the development of driverless cars, said the researchers.

4 Dec 2018

Imaging News and Research

Avoidant grievers unconsciously monitor and block mind-wandering contents, study shows

Novel 3D printing workflow helps predict leaky heart valves

Ezogabine treatment reduces motor neuron excitability in ALS patients, study shows

Episodic memory tests help in predicting brain atrophy and Alzheimer’s disease

Updated breast cancer screening guideline highlights importance of shared decision-making

Researchers discover a 'blind spot' in atomic force microscopy

CZI announces funding for open-source software efforts to improve image analysis in biomedicine

New diagnostic tools may help identify breast cancer patients who could benefit from targeted therapies

Researchers use new methods to optimize treatments for tuberculosis meningitis

Study sheds new light on microtubule binding proteins and microtubule dynamics

Researchers are developing blood test to diagnose or predict Alzheimer's disease

Individual neurons located within the brain have implications for psychiatric diseases

Researchers develop biosensors to detect and measure metastatic potential of cancer cells

Functional ultrasound imaging can reveal brain activity maps of mice for specific behaviors

Cancer patients who take beta-blocker along with breast cancer drug have less heart damage

NIH-funded tissue chips that model aspects of the human immune system sent to space

CEASE intervention enhances delivery of smoking cessation assistance for breastfeeding mothers

New discovery offers parameter for predicting progression of oral cancer

New study supports use of ZnO nanoparticles in sunscreens

Yale researchers predict how people's eyes move when viewing natural scenes

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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