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Study identifies new altered neural circuits in Huntington’s disease

Huntington's disease is a genetically-based neurodegenerative disorder that causes motor, cognitive and psychiatric disorders in the affected individuals.

7 Jun 2023

New insights into how aggressive cancer cells proliferate and propagate the disease

Not all cancer metastases have the same destructive effect. Researchers demonstrate different mechanisms in experiments.

7 Jun 2023

Promising targeted therapy offers new hope to certain patients with advanced pancreatic cancer

A promising new targeted cancer therapy will soon be available to certain patients with advanced pancreatic cancer – from the comfort of their home.

7 Jun 2023

Burnout threatens primary care workforce and doctors’ mental health

Melanie Gray Miller, a 30-year-old physician, wiped away tears as she described the isolation she felt after losing a beloved patient.

7 Jun 2023

Is discontinuing universal SARS-CoV-2 testing at hospital admission in England and Scotland associated with increased hospital-onset infections?

Researchers performed a time series analysis using public data sets from both nations to examine whether this discontinuation resulted in a surge in hospital-onset COVID-19 cases.

7 Jun 2023

Participation in physical activity should be promoted in those with high genetic risk of type two diabetes

Study aimed to understand whether there is a dose-response association between physical activity and incident type 2 diabetes.

7 Jun 2023

Estimate of treatment effect modification by comorbidity using participant data

Treatment efficacy for a broad range of chronic diseases does not differ depending on patients' comorbidities, according to a new study publishing June 6th in the open access journal PLOS Medicine by David McAllister of the University of Glasgow, UK, and colleagues.

7 Jun 2023

Study highlights the urgent need for a higher level of care for nursing home residents with AD

The quality of care for nursing home residents with Alzheimer's disease and related dementias is best when they are in the majority, but most facilities also accommodate a heterogeneous population, where specialized staff training is limited, according to a study led by the University of California, Irvine.

7 Jun 2023

Differences in tumor mutation burden are a major reason for divergence: Study

The expected course of a patient's cancer prognosis has traditionally been judged by its type, stage and microscopic aggressiveness, but patients with the same presentation can still have widely divergent outcomes. Researchers from Vanderbilt-Ingram Cancer Center have discovered that differences in tumor mutation burden are a major reason for this divergence.

7 Jun 2023

New deep learning model lays the foundation for specialized diagnostic models

Mount Sinai researchers have developed an innovative artificial intelligence (AI) model for electrocardiogram (ECG) analysis that allows for the interpretation of ECGs as language. This approach can enhance the accuracy and effectiveness of ECG-related diagnoses, especially for cardiac conditions where limited data is available on which to train.

7 Jun 2023

New strategy to grow and measure how tumor organoids respond to therapy

Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a new method to bioprint miniature tumor organoids that are designed to mimic the function and architecture of real tumors. The improved process allows researchers to use an advanced imaging method to study and analyze individual organoids in great detail, which can help researchers identify personalized treatments for people with rare or hard-to-treat cancers.

7 Jun 2023

Wearable sleep devices hold promise in positively impacting sleep health among marginalized people

In a new study, titled "Acceptability and Usability of a Wearable Device for Sleep Health Among English- and Spanish-Speaking Patients in the Safety Net: Qualitative Analysis," researchers found that wearable sleep devices hold promise in positively impacting sleep health among marginalized populations.

6 Jun 2023

New insight from patients on what helps or hinders medication-assisted opioid use disorder treatment

Patients would be more willing to enter medication-assisted treatment for opioid use disorder if existing stigmas were reduced and more accessible payment support was readily available, a West Virginia University study finds.

6 Jun 2023

Spinal neural circuit dysfunction mediates movement symptoms in dystonia

Many neurological conditions that involve involuntary muscle contractions have long been considered as diseases of the brain.

6 Jun 2023

Researchers characterize the expression of cardiac proteins during embryonic heart development

Researchers at the UNC School of Medicine, UNC McAllister Heart Institute, and the UNC Lineberger Comprehensive Cancer Center characterized the expression of thousands of cardiac proteins during eight critical stages of embryonic heart development.

6 Jun 2023

AI algorithms outperform the standard clinical risk model for predicting breast cancer risk

In a large study of thousands of mammograms, artificial intelligence (AI) algorithms outperformed the standard clinical risk model for predicting the five-year risk for breast cancer. The results of the study were published in Radiology, a journal of the Radiological Society of North America (RSNA).

6 Jun 2023

Life-changing procedure using new aortic valve device clears way for patient in need of liver transplant and hip replacement

Janice Couch, 62, a retired pre-school teacher from Grand Rapids, Michigan, is finally physically ready to receive two procedures that stand to change her life, thanks to Henry Ford Health interventional cardiologists who paved the way by implanting a new aortic valve device for the first time in the health system's history.

6 Jun 2023

SickKids scientists shine light on the complex genetics that underlie blood pressure regulation

Scientists at The Hospital for Sick Children (SickKids) are delving deep into the non-coding genome to unravel the complex genetics that underlie blood pressure regulation and hypertension (high blood pressure) – the leading cause of cardiovascular disease affecting 1.25 billion people worldwide.

6 Jun 2023

COLOTECT 1.0 receives market authorization from Malaysia's Medical Device Authority

Recently, BGI Genomics' COLOTECT 1.0 DNA Methylation Detection Kit for Human SDC2, ADHFE1, and PPP2R5C Genes (Real-Time PCR), Sample Pretreatment Kit for Methylation Detection, DNA Isolation Kit, Stool Sample Collection Kit have received market authorization from Malaysia's Medical Device Authority (hereinafter referred to as MDA).

6 Jun 2023

Therapeutic nanocarriers engineered from adult skin cells show promise for treating lung injury

Therapeutic nanocarriers engineered from adult skin cells can curb inflammation and tissue injury in damaged mouse lungs, new research shows, hinting at the promise of a treatment for lungs severely injured by infection or trauma.

6 Jun 2023

Medicine News and Research

Study identifies new altered neural circuits in Huntington’s disease

New insights into how aggressive cancer cells proliferate and propagate the disease

Promising targeted therapy offers new hope to certain patients with advanced pancreatic cancer

Burnout threatens primary care workforce and doctors’ mental health

Is discontinuing universal SARS-CoV-2 testing at hospital admission in England and Scotland associated with increased hospital-onset infections?

Participation in physical activity should be promoted in those with high genetic risk of type two diabetes

Estimate of treatment effect modification by comorbidity using participant data

Study highlights the urgent need for a higher level of care for nursing home residents with AD

Differences in tumor mutation burden are a major reason for divergence: Study

New deep learning model lays the foundation for specialized diagnostic models

New strategy to grow and measure how tumor organoids respond to therapy

Wearable sleep devices hold promise in positively impacting sleep health among marginalized people

New insight from patients on what helps or hinders medication-assisted opioid use disorder treatment

Spinal neural circuit dysfunction mediates movement symptoms in dystonia

Researchers characterize the expression of cardiac proteins during embryonic heart development

AI algorithms outperform the standard clinical risk model for predicting breast cancer risk

Life-changing procedure using new aortic valve device clears way for patient in need of liver transplant and hip replacement

SickKids scientists shine light on the complex genetics that underlie blood pressure regulation

COLOTECT 1.0 receives market authorization from Malaysia's Medical Device Authority

Therapeutic nanocarriers engineered from adult skin cells show promise for treating lung injury

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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