Antigen News and Research

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Reaction to DTaP vaccine finds no help from ibuprofen, acetaminophen

A red splotch forms where most preschoolers get their fifth, and last, shot of the acellular diphtheria-tetanus-pertussis (DTaP) vaccine, and it can last a few days.

1 Mar 2006

Delayed surgical treatment may combat overtreatment of prostate cancer

Delayed surgical treatment for patients with small, low-grade prostate cancer tumors was not associated with lowered curability, according to a study in the March 1 issue of the Journal of the National Cancer Institute.

1 Mar 2006

Defective apoptosis of dendritic cells can be a critical component of autoimmune diseases

The failure of programming that sparks the death of dendritic cells - those that activate the immune system - can initiate autoimmune disease, said researchers from Baylor College of Medicine in a report that appears in the current issue of the journal Science.

1 Mar 2006

Researchers transplant insulin-producing neonatal porcine islet cells into monkeys

A team of researchers from the University of Alberta, the Yerkes National Primate Research Center of Emory University and the Emory Transplant Center has successfully transplanted insulin-producing neonatal porcine islet cells into monkeys, a procedure the researchers say represents a promising intermediate solution to the critical supply problem in clinical islet cell transplantation.

27 Feb 2006

Study shows survival advantage for men treated with radical prostatectomy or radiation therapy compared to observation

A new study shows older men with early stage prostate cancer survive longer if they are treated versus not being treated in favor of the "watchful waiting" approach advocated by many physicians for older men with other health problems.

27 Feb 2006

New generation gold-based drugs for treating rheumatoid arthritis

Gold compounds have been used for the treatment of rheumatoid arthritis and other autoimmune diseases for more than 75 years, but until now, how the metals work has been a mystery.

27 Feb 2006

$1 million of mesothelioma research funding

The Mesothelioma Applied Research Foundation (MARF) has announced awards of almost $1 million in additional research funding aimed at curing mesothelioma.

24 Feb 2006

Selective T cell stimulation could help improve treatment of autoimmune disease and cancer

The findings could also be significant for developing new ways to help patients with autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, or juvenile diabetes.

23 Feb 2006

Ebola DNA vaccine shows promise

Vical Incorporated has announced that an Ebola vaccine candidate administered using Vical's proprietary DNA delivery technology was safe and well tolerated, and produced both antibody and T-cell Ebola-specific responses in all healthy volunteers who received the full 3 doses of vaccine.

21 Feb 2006

Interleukin-15 encourages CD8+ T cells to proliferate and reduces their tolerance to tumor antigens

Certain types of white blood cells assist the body in destroying cancerous tumors. Among these are CD8+ T cells. The T is for thymus, the gland near the base of the throat that both raises up and weeds out blood cells involved in immune responses.

20 Feb 2006

New flu vaccine takes weeks to mass produce

Using cell-based methods researchers have developed a commercially viable method for mass producing effective vaccines against potential pandemic influenza strains in weeks instead of the months required for traditional egg-based vaccines.

17 Feb 2006

Sanofi pasteur delivers more H5N1 vaccines to U.S. Government

Sanofi pasteur has delivered more H5N1 vaccine to the U.S. government including investigational doses formulated with an adjuvant.

7 Feb 2006

New technology for accelerating development of vaccines against H5N1 flu

Technology that enables scientists to identify targets for the development of vaccines against viruses such as H5N1 in weeks rather than months has entered a pilot study at ProImmune, Oxford, UK.

7 Feb 2006

Source of crucial immune cell in the skin discovered - may lead to tumor immunotherapy

Mount Sinai School of Medicine researchers have identified the precursors of cells in the skin that are part of the first line of defense against invading pathogens. The study appears on Nature Immunology's website.

7 Feb 2006

Black men least likely to get prostate cancer screening even during peak ages of risk

The men most at risk for aggressive prostate cancer - black men with a family history - are the least likely to get screening even during peak ages of risk, researchers say.

5 Feb 2006

Experts counter study's claim - men should continue prostate exams

A man has a one in six chance of being diagnosed with prostate cancer. Each year, more than 230,000 men are diagnosed with the disease. Doctors have traditionally recommended two tests for the early detection of prostate cancer; the prostate specific antigen (PSA) test and digital rectal exam (DRE) are used to detect abnormalities with the prostate gland.

23 Jan 2006

SSRI antidepressants may also affect human immune system

Drugs that treat depression by manipulating the neurotransmitter serotonin in the brain may also affect the user's immune system in ways that are not yet understood, say scientists from Georgetown University Medical Center and a Canadian research institute.

23 Jan 2006