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Researchers produce a multi-scale map of protein assemblies in the DNA damage response

Writing in the May 22, 2023 issue of Cell Systems, a diverse team of scientists, led by researchers at University of California San Diego School of Medicine, have produced a novel map that depicts the human body's enormously complicated and highly evolved system for addressing and repairing DNA damage -; a cause and consequence of many diseases.

22 May 2023

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The clinical outcomes of patients with active RA can be improved using anti-rheumatic medications, such as methotrexate (MTX).

22 May 2023

Study could help understand why limiting sugary foods can ease symptoms for IBD patients

Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.

22 May 2023

$OST performs better than FRAX in determining osteoporotic fracture risk in younger postmenopausal women$

OST performs better than FRAX in determining osteoporotic fracture risk in younger postmenopausal women

The commonly used Fracture Risk Assessment Tool (FRAX), which includes self-identified race and ethnicity information, and the Osteoporosis Self-Assessment Tool (OST), which does not, had suboptimal performance in determining major osteoporotic fracture risk across racial/ethnic categories in younger postmenopausal women.

22 May 2023

Improved version of leadless pacemaker will soon be available for all patients

Every year more than one million people receive a pacemaker. Until now, leadless versions were only available for 20% of these patients.

22 May 2023

Honokiol inhibits replication of SARS-CoV-2 in several cell types

A compound called honokiol, which is found in the bark of multiple species of magnolia tree, inhibits replication of SARS-CoV-2 virus in several types of cells, according to a team of researchers in the Netherlands.

22 May 2023

Air pollution may increase risk of death in heart failure patients

Heart failure patients are at increased risk of dying from their condition on polluted days and up to two days afterwards, according to research presented today at Heart Failure 2023, a scientific congress of the European Society of Cardiology.

22 May 2023

Newly discovered molecule effectively destroys senescent cells

Over time, the body's cells stop working properly and begin to accumulate, which eventually leads to tissues aging.

22 May 2023

Regular exercise may reduce bleeding in individuals with intracerebral hemorrhage

Regular physical activity and exercise may reduce bleeding in individuals with intracerebral hemorrhage, a University of Gothenburg study shows.

22 May 2023

Study finds higher risk of mortality among women than men after heart attack

Women are more than twice as likely to die after a heart attack than men, according to research presented today at Heart Failure 2023, a scientific congress of the European Society of Cardiology.

22 May 2023

LSHTM researcher receives £1.8 million to help reduce the impact of alcohol-related harms in India

Dr Abhijit Nadkarni from the London School of Hygiene & Tropical Medicine (LSHTM) has been awarded a prestigious Global Research Professorship from the National Institute for Health and Care Research (NIHR).

22 May 2023

Cancer researchers join together to fight lethal childhood brain cancer

Virginia Tech researchers with the Fralin Biomedical Research Institute at VTC have joined a Children's National Hospital effort to treat deadly brain tumors with ultrahigh frequency sound waves.

22 May 2023

Targeting mucus plugs could help prevent deaths from COPD, study suggests

A retrospective analysis of patient data from the COPDGene study suggests that targeting mucus plugs could help prevent deaths from chronic obstructive pulmonary disease-;the fourth leading cause of death in the United States.

22 May 2023

The role of RNA splicing in one of the deadliest forms of pancreatic cancer

In this interview, we spoke to Adrian Krainer, a Professor at Cold Spring Harbor Laboratory, about his latest research into the role of RNA splicing in one of the deadliest forms of pancreatic cancer.

22 May 2023

New device makes a heart procedure safer for patients with atrial fibrillation

A new device invented with the help of an electrophysiologist at The Ohio State University Wexner Medical Center makes a heart procedure safer for patients suffering from atrial fibrillation (AFib), a common irregular heart rhythm.

22 May 2023

Opentrons Flex™ Lab Robot Launches to Accelerate Bioautomation Across Thousands of Life Science Experiments

Opentrons, a leader in lab automation, announces the launch of its Opentrons Flex robot, a new generation of affordable and easy-to-program liquid-handling lab robots designed to level the playing field for labs of all sizes and bring advanced lab automation to more researchers than ever before.

From Opentrons 22 May 2023

Amyloid-removing drug shows promise for the treatment of stiff-heart syndrome

Transthyretin-related cardiac amyloidosis is a progressive disease characterized by the deposition of amyloid protein fibrils in the heart. Amyloid fibril deposition thickens and stiffens the heart walls, and the disease is also known as stiff-heart syndrome.

22 May 2023

Study shows potential benefit of sacubitril/valsartan in heart failure patients with EF over 40%

Sacubitril/valsartan leads to greater reduction in plasma NT-proBNP levels compared to valsartan alone after stabilization for worsening heart failure in patients with an ejection fraction (EF) above 40%, according to late breaking science presented today at Heart Failure 2023, a scientific congress of the European Society of Cardiology (ESC), and published in the Journal of the American College of Cardiology.

22 May 2023

Heart attack patients with strong legs less likely to develop heart failure

People with strong legs are less likely to develop heart failure after a heart attack, according to research presented today at Heart Failure 2023, a scientific congress of the European Society of Cardiology.

22 May 2023

Remote pulmonary artery pressure monitoring improves quality of life, reduces heart failure hospitalizations

The first investigator-initiated study of remote pulmonary artery pressure monitoring has found that it improves quality of life and reduces heart failure hospitalizations in patients with chronic heart failure.

22 May 2023

Medicine News and Research

Researchers produce a multi-scale map of protein assemblies in the DNA damage response

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Study could help understand why limiting sugary foods can ease symptoms for IBD patients

OST performs better than FRAX in determining osteoporotic fracture risk in younger postmenopausal women

Improved version of leadless pacemaker will soon be available for all patients

Honokiol inhibits replication of SARS-CoV-2 in several cell types

Air pollution may increase risk of death in heart failure patients

Newly discovered molecule effectively destroys senescent cells

Regular exercise may reduce bleeding in individuals with intracerebral hemorrhage

Study finds higher risk of mortality among women than men after heart attack

LSHTM researcher receives £1.8 million to help reduce the impact of alcohol-related harms in India

Cancer researchers join together to fight lethal childhood brain cancer

Targeting mucus plugs could help prevent deaths from COPD, study suggests

The role of RNA splicing in one of the deadliest forms of pancreatic cancer

New device makes a heart procedure safer for patients with atrial fibrillation

Opentrons Flex™ Lab Robot Launches to Accelerate Bioautomation Across Thousands of Life Science Experiments

Amyloid-removing drug shows promise for the treatment of stiff-heart syndrome

Study shows potential benefit of sacubitril/valsartan in heart failure patients with EF over 40%

Heart attack patients with strong legs less likely to develop heart failure

Remote pulmonary artery pressure monitoring improves quality of life, reduces heart failure hospitalizations

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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