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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

New study delves deeper into individual genomic differences than ever before

Human genomes vary quite a bit from individual to individual. These differences include single nucleotide changes, or "spelling mistakes" in the DNA sequence, but even more variation comes from structural variants, which include additions, deletions and rearrangements of large segments of DNA.

17 Apr 2019

Japanese researchers explain how inflammation causes gastric tumors

In 1982, researchers reported a link between chronic gastritis and stomach bacterium Helicobacter pylori, triggering a flurry of research into this newly-identified pathogen.

16 Apr 2019

Cause of cancer is 'written' in our DNA as unique 'fingerprints'

Scientists have discovered that the cause of cancer is “written” within the DNA of tumors, a finding that could help doctors to decide on the best treatment for a patient.

16 Apr 2019

Researchers identify cause of inherited metabolic disorder

A new study from BC Children's Hospital, the University of British Columbia (UBC) and an international team of researchers published in the New England Journal of Medicine is the first to identify a rarely-seen type of DNA mutation as the cause of an inherited metabolic disorder.

16 Apr 2019

Coagulation factor VIIa prevents bleeds in hemophilia animal models

Hematology researchers have further refined how a treatment currently used on an urgent basis to control bleeding in hemophilia patients holds promise as a preventive treatment as well.

16 Apr 2019

Phenols in purple corn may fight obesity, inflammation and diabetes, mice study shows

Scientists at the University of Illinois have developed new hybrids of purple corn containing different combinations of phytochemicals that may fight obesity, inflammation and diabetes, a new study in mice indicates.

16 Apr 2019

CRISPR-scanning could lead to more effective treatments for cancer

11,000 people are predicted to die from acute myeloid leukemia in 2019, according to the American Cancer Society. The cancer starts in the bone marrow. There, mutated genes fail to prevent blood cells from replicating again and again and again, growing tumors.

16 Apr 2019

Spatial orgnization of the genome can be altered using small molecules

Researchers have discovered that the spatial organization of the genome can be altered using small molecule compounds which are considered as promising anti-cancer drugs.

16 Apr 2019

New catalog of DNA mutation 'fingerprints' could help doctors pinpoint cancer culprits

Scientists in Cambridge and London have developed a catalog of DNA mutation 'fingerprints' that could help doctors pinpoint the environmental culprit responsible for a patient's tumor - including showing some of the fingerprints left in lung tumors by specific chemicals found in tobacco smoke.

16 Apr 2019

Restoring function of 'misregulated' cancer-fighting genes

Working with human colon cancer cells and mice, researchers led by experts at the Johns Hopkins Kimmel Cancer Center say they have successfully blocked the activity of portions of a protein known as UHRF1 and restored the function of hundreds of cancer-fighting genes that became "misregulated" by the disease.

15 Apr 2019

Spotlight on ECCMID 2019: Detecting Disease & Managing Infections

This article covers some of the highlights of ECCMID 2019, with insights into some of the companies and products being featured at the event.

From ESCMID 15 Apr 2019

Potential new therapeutic approach identified for neuroblastoma tumors

Research led by Michael Lan, PhD, Professor of Pediatrics and Genetics at LSU Health New Orleans School of Medicine, found that a compound named 5'-iodotubercidin (5'-IT) suppresses the growth of neuroblastoma cells and identified a potential new therapeutic approach for the disease.

12 Apr 2019