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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

High Throughput Nucleic Acid Purification Simplified

Labs demand purity and flexibility for high throughput nucleic acid purification, while needing to complete difficult downstream analysis, for example NGS.

From Promega Corporation 9 Apr 2019

Study compares library preparation and sequencing platforms for single-cell RNA-sequencing

Researchers from University of Southern Denmark, Wellcome Sanger Institute and BGI, today published a study in the journal Genome Biology comparing the library preparation and sequencing platforms for single-cell RNA-sequencing.

9 Apr 2019

Study finds no major epigenetic differences between space astronaut and his earthbound twin brother

In a landmark study, a group of U.S. scientists from Johns Hopkins, Stanford University and other institutions has found no long-lasting, major differences between the epigenomes of astronaut Scott Kelly, who spent a year in space aboard the International Space Station, and his twin brother, Mark, who remained on Earth.

9 Apr 2019

Testing how well wastewater disinfection methods affect antibiotic resistance genes

Each year at least 2 million Americans are infected with bacteria that cannot be treated with antibiotics, and at least 23,000 of these people die, according to the Centers for Disease Control.

9 Apr 2019

Cellular protein could take on role of restriction factor for hepatitis B virus

Hepatitis B is a viral liver infection that can lead to acute or chronic conditions. Although there is a vaccine that offers protection against the virus, current treatments which prevent the virus from replicating are not curative for infected individuals.

8 Apr 2019

New clinical trials to investigate combination immunotherapy for treating advanced cancers

City of Hope physician-scientists recently opened two clinical trials to investigate a combination of cytokines and immunotherapy that may be able to transform nearly-impossible-to-treat cancer into a disease that can be corralled into remission.

8 Apr 2019

Gum disease bacterium releases toxins that may cause Alzheimer's

Researchers have provided the strongest evidence to date that a bacterium involved in periodontitis contributes to the development of Alzheimer’s disease, rheumatoid arthritis and aspiration pneumonia.

8 Apr 2019

Synthetic antibody rapidly prevents Zika infection in mice and non-human primates

A DNA-encoded monoclonal antibody prevents Zika infection in mice and non-human primates, researchers report April 5 in the journal Molecular Therapy.

8 Apr 2019

Gut microbiome may drive HIV transmission risk in high-risk men

Gut microbes from high HIV-risk men who have sex with men drive immune activation in mice and HIV infection in cells, according to a study published April 4 in the open-access journal PLOS Pathogens by Brent Palmer and Catherine Lozupone of the University of Colorado Anschutz, and colleagues.

8 Apr 2019

A gene regulatory multi-tool plays key role in unjamming the genome after DNA damage

A protein complex that is involved in nearly every step in the regulatory control of gene expression in cells has now been shown also to play a key role in clearing potential traffic jams in the production of RNA.

5 Apr 2019

Researchers discover how specific mutation obstructs healthy blood cell maturation

In the veins, stem cells constantly mature and develop into different blood cells that are necessary for the body to work properly.

5 Apr 2019

Researchers identify genetic mutations that can promote regeneration after liver damage

Researchers at the Children's Medical Center Research Institute at UT Southwestern have identified genetic mutations that accumulate in the adult liver that can promote regeneration in the context of chronic liver damage.

5 Apr 2019

Novel technology set to play key role in the fight against anti-microbial resistance

Increasing pressures on health services have led to the over-prescription of commonly used antibiotics, more instances of mis-prescription and subsequently, the emergence of antibiotic resistance and an increased reliance on antibiotics of last resort.

5 Apr 2019

New Research Unit funded by DFG aims to improve diagnosis of genetic diseases

How can we improve the identification and prompt diagnosis of genetic diseases? A new Research Unit at Charité - Universitätsmedizin Berlin will set out to identify and reliably interpret important non-coding sections of our genomes in the hope of finding the diagnosis for unsolved diseases.

5 Apr 2019

Research unravels possible factor for female bias in lupus

The autoimmune disease lupus, which can cause fatigue, a facial rash, and joint pain, strikes females far more often than males. Eight-five percent of people with lupus are female, and their second X chromosome seems partly to blame.

5 Apr 2019

Poverty can become embedded across wide swaths of the genome, study finds

A new Northwestern University study challenges prevailing understandings of genes as immutable features of biology that are fixed at conception.

4 Apr 2019

AACR Annual Meeting 2019 Highlighted Latest Advances in Cancer Research

On Friday, March 29 to Wednesday, April 3, the Georgia World Congress Center in Atlanta, Georgia, hosted the AACR Annual Meeting 2019.

From 10x Genomics, Inc. 4 Apr 2019

Bronchiectasis patients often display high sensitivity to airborne allergens

An international research team led by Nanyang Technological University, Singapore (NTU Singapore) has found that patients with the lung disease bronchiectasis also often display sensitivity to airborne allergens, and has highlighted the particular role that fungi appear to play.

4 Apr 2019

New all-in-one immunotherapy approach kicks out hiding HIV and also kills it

In a first on the quest to cure HIV, University of Pittsburgh Graduate School of Public Health scientists report today in EBioMedicine that they've developed an all-in-one immunotherapy approach that not only kicks HIV out of hiding in the immune system, but also kills it.

4 Apr 2019

New technology could change the way gene editing is approached in future

Gene editing has been a much sought after and controversial technology. Last month, part of the World Health Organization called for an international registry to track all research into editing the human genome.

4 Apr 2019

DNA News and Research

Further Reading

High Throughput Nucleic Acid Purification Simplified

Study compares library preparation and sequencing platforms for single-cell RNA-sequencing

Study finds no major epigenetic differences between space astronaut and his earthbound twin brother

Testing how well wastewater disinfection methods affect antibiotic resistance genes

Cellular protein could take on role of restriction factor for hepatitis B virus

New clinical trials to investigate combination immunotherapy for treating advanced cancers

Gum disease bacterium releases toxins that may cause Alzheimer's

Synthetic antibody rapidly prevents Zika infection in mice and non-human primates

Gut microbiome may drive HIV transmission risk in high-risk men

A gene regulatory multi-tool plays key role in unjamming the genome after DNA damage

Researchers discover how specific mutation obstructs healthy blood cell maturation

Researchers identify genetic mutations that can promote regeneration after liver damage

Novel technology set to play key role in the fight against anti-microbial resistance

New Research Unit funded by DFG aims to improve diagnosis of genetic diseases

Research unravels possible factor for female bias in lupus

Poverty can become embedded across wide swaths of the genome, study finds

AACR Annual Meeting 2019 Highlighted Latest Advances in Cancer Research

Bronchiectasis patients often display high sensitivity to airborne allergens

New all-in-one immunotherapy approach kicks out hiding HIV and also kills it

New technology could change the way gene editing is approached in future

eBook: Exploring the Cell Cycle and DNA Damage and Repair eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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