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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Novel strategy to ameliorate symptoms of mitochondrial disease

Diseases affecting mitochondria, the powerhouses of our cells, are often caused by mutations in the mitochondrial DNA. Symptoms of such mitochondrial diseases in mice can be ameliorated by increasing their levels of mitochondrial DNA, according to a study by researchers at Karolinska Institutet.

3 Apr 2019

Salk researchers reveal new role for a driver of metastatic cancers

Metastatic ovarian, prostate and breast cancers are notoriously difficult to treat and often deadly. Now, Salk Institute researchers have revealed a new role for the CDK12 protein. The findings were published in the print version of Genes & Development on April 1, 2019.

3 Apr 2019

G:BOX Chemi XX6 imager used to speed up analysis of proteins linked with breast cancer

Syngene, a world-leading manufacturer of image analysis solutions, today announced its G:BOX Chemi XX6 multi-application imager is being utilized by scientists at a major London university to speed up analysis of proteins, DNA and cells associated with breast and a range of other cancer types.

From Syngene 3 Apr 2019

New Chromatrap ChIP-seq kit performs chromatin immunoprecipitation with unparalleled sensitivity

Porvair Sciences announces version 2.0 of its Chromatrap® ChIP-seq kit - developed to perform chromatin immunoprecipitation with unparalleled sensitivity.

From Chromatrap® - Porvair Sciences Ltd 3 Apr 2019

Molecular biologists develop pipeline to create and screen new lantibiotic peptides

Nature has provided us with lots of antimicrobials. However, given the rapid increase of antimicrobial resistance, there is a need for the development of new-to-nature antibiotics. Lantibiotics are an interesting option.

3 Apr 2019

Protein discovery opens door for new options in diagnosis and therapy of cancer

Oncologists at the University and University Hospital in Tübingen have discovered a new protein variant that plays an important role in the development and therapy response of cancer.

3 Apr 2019

Study reveals new strategy to combat antibiotic resistance

A new strategy to combat antibiotic resistance has emerged from a study led by researchers at Baylor College of Medicine. Published in the journal Molecular Cell, the report reveals for the first time how bacteria evolve mutations that confer antibiotic resistance and that this process can be inhibited with FDA-approved drug edaravone.

2 Apr 2019

Gut microbiota can help predict occurrence of colorectal cancer

Gut microbiota - the population of microbes that live in our intestine - can be used to predict the occurrence of colorectal cancer, the second most common type of cancer in women and the third in men.

1 Apr 2019

Measuring estrogen byproducts can help predict survival for breast cancer patients

Researchers from the University of North Carolina Lineberger Comprehensive Cancer Center found preliminary evidence that measuring byproducts of the hormone estrogen can help them predict survival for women with breast cancer.

1 Apr 2019

Researchers discover natural gene therapy for intractable skin disease

Pathogenic gene mutations causing a type of intractable skin disease can be eliminated from some parts of patients' skin as they age, according to Hokkaido University researchers and their collaborators in Japan. This represents a form of natural gene therapy.

1 Apr 2019

Research demonstrates clinical utility of ddPCR-powered liquid biopsy at 2019 AACR Annual Meeting

New research demonstrating the clinical utility of Bio-Rad's Droplet Digital PCR powered liquid biopsy will be presented this week during the 2019 American Association for Cancer Research Annual Meeting in Atlanta, March 29-April 3.

30 Mar 2019

Seemingly identical bacteria may have a different effect

Our gut microbiome - the complement of bacteria we carry around in our intestines - has been linked to everything from obesity and diabetes to heart disease and even neurological disorders and cancer.

30 Mar 2019

Novel EU-funded project in the field of genomics

The European Advanced infraStructure for Innovative Genomics (EASI-Genomics), a project funded under the European Union's research and innovation programme Horizon 2020, will provide researchers free-of-charge access to cutting-edge European genomics facilities.

30 Mar 2019

Cellular mechanism that connects smoking during pregnancy and baby’s obesity risk identified

Using foreskin tissue from newborn circumcisions, a group of researchers have identified a potential cellular mechanism that connects a mother's smoking while pregnant with an increased risk of offspring obesity later in life.

30 Mar 2019

WHO guidelines for chronic hepatitis B fail to detect half of the patients in Ethiopia needing treatment

Current World Health Organization (WHO) guidelines for chronic hepatitis B (CHB) fail to detect half of the patients in need of treatment in Ethiopia, report scientists in the Journal of Hepatology, published by Elsevier.

29 Mar 2019

Scientists identify two, extremely rare genetic variants linked to Alzheimer disease

Researchers have identified two, extremely rare genetic variants linked to Alzheimer disease (AD) for the first time.

29 Mar 2019

Scientists target metastasis in the battle against cancer

An experimental combination drug therapy attacking the DNA integrity of cancer cells is showing promise for a possible new cancer therapy in the future.

29 Mar 2019

Research leads to innovative method of diagnosing rare hereditary diseases

A new sophisticated computational model, developed by scientists at Lawson Health Research Institute, is bringing an innovative method of diagnosing rare hereditary conditions.

29 Mar 2019

Promising new way to thwart tricky Mtb pathogen

Tuberculosis, an ancient and notoriously difficult disease to treat, has killed millions through the course of human history; and the antibiotics that have been used to fight the disease in recent history are becoming less and less effective.

29 Mar 2019

Researchers develop new strategy to treat sickle cell disease and beta thalassemia

Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and the University of Massachusetts Medical School have developed a strategy to treat two of the most common inherited blood diseases -- sickle cell disease and beta thalassemia -- applying CRISPR-Cas9 gene editing to patients' own blood stem cells.

29 Mar 2019

DNA News and Research

Further Reading

Novel strategy to ameliorate symptoms of mitochondrial disease

Salk researchers reveal new role for a driver of metastatic cancers

G:BOX Chemi XX6 imager used to speed up analysis of proteins linked with breast cancer

New Chromatrap ChIP-seq kit performs chromatin immunoprecipitation with unparalleled sensitivity

Molecular biologists develop pipeline to create and screen new lantibiotic peptides

Protein discovery opens door for new options in diagnosis and therapy of cancer

Study reveals new strategy to combat antibiotic resistance

Gut microbiota can help predict occurrence of colorectal cancer

Measuring estrogen byproducts can help predict survival for breast cancer patients

Researchers discover natural gene therapy for intractable skin disease

Research demonstrates clinical utility of ddPCR-powered liquid biopsy at 2019 AACR Annual Meeting

Seemingly identical bacteria may have a different effect

Novel EU-funded project in the field of genomics

Cellular mechanism that connects smoking during pregnancy and baby’s obesity risk identified

WHO guidelines for chronic hepatitis B fail to detect half of the patients in Ethiopia needing treatment

Scientists identify two, extremely rare genetic variants linked to Alzheimer disease

Scientists target metastasis in the battle against cancer

Research leads to innovative method of diagnosing rare hereditary diseases

Promising new way to thwart tricky Mtb pathogen

Researchers develop new strategy to treat sickle cell disease and beta thalassemia

eBook: A guide to RNA sequencing eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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