Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Novel approach identifies potent drug-like molecules that bind to cancer protein of interest

Researchers at Baylor College of Medicine and Texas Children's Hospital have identified potent, highly specific compounds that interfere with bromodomain (BD)-containing proteins involved in cancer.

3 Jun 2022

New method to combat malaria turns the disease against itself

A new method to combat malaria which sees the disease turn against itself could offer an effective treatment for the hundreds of millions of people infected globally each year, as the efficacy of current antimalarial drugs weakens.

3 Jun 2022

Collaborative effort uncovers a new type of triterpenes

A remarkable discovery and collaborative effort have revealed a new type of triterpenes, a group of organic compounds which are an important source of many medicines.

1 Jun 2022

Dr. Paul Brooks is CN Bio's New Chief Business Officer

CN Bio, a leading Organ-on-a-chip Company (OOC) that designs and manufactures single- and multi-organ microphysiological systems (MPS), today announced the appointment of Dr. Paul Brooks as Chief Business Officer.

From CN-Bio 25 May 2022

Insilico Medicine nominates novel preclinical candidate targeting 3CL protease for COVID-19 treatment

Insilico Medicine, a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced its nomination of a novel preclinical candidate (PCC) targeting 3C-like (3CL) protease for the treatment of COVID-19.

24 May 2022

Researchers discover osteogenetic oligodeoxynucleotide that promotes bone differentiation

Bone tissue homeostasis is maintained by a balance between bone formation by osteoblasts and bone resorption by osteoclasts.

23 May 2022

University of Minnesota receives $66 million to establish new antiviral drug discovery center

The University of Minnesota has received $66 million from the National Institute of Allergy and Infectious Diseases to establish a center to develop antiviral drugs for pandemic-level viruses, including SARS-CoV-2.

23 May 2022

UNC-Chapel Hill secures $65 million NIH grant for establishing Antiviral Drug Discovery Center

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health awarded the UNC Gillings School of Global Public Health a $65 million grant establishing an Antiviral Drug Discovery Center to develop oral antivirals that can combat pandemic-level viruses like COVID-19.

20 May 2022

New funding boost to combat antibiotic resistance

Antibiotics have saved countless lives since they were introduced in the 1940s, curing infections and making procedures like chemotherapy and surgeries safer. But their effectiveness is waning.

19 May 2022

New approach to elevate health and well-being by optimizing late-life brain capital

Within many societies and cultures around the world, older adults are too often undervalued and underappreciated, according to a new article in the journal Innovation in Aging.

18 May 2022

NIH awards $577 million to establish AViDD Centers for Pathogens of Pandemic Concern

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded approximately $577 million to establish nine Antiviral Drug Discovery (AViDD) Centers for Pathogens of Pandemic Concern.

18 May 2022

A*STAR, NHCS, NUS, and Novo Nordisk partner to study the mechanisms underlying heart failure

The Agency for Science, Technology and Research's Genome Institute of Singapore and Bioinformatics Institute, as well as the National Heart Centre Singapore, National University of Singapore, and pharmaceutical company Novo Nordisk have signed an agreement to study the mechanisms underlying cardiovascular disease progression-; especially the condition called heart failure with preserved ejection fraction (HFpEF).

13 May 2022

bit.bio launches Huntington’s disease human cell model

First neurodegenerative disease model launched from bit.bio's new ioDisease Model portfolio.

From bit.bio 10 May 2022

Dotmatics Biology Solution for Antibody Discovery streamlines data collection and workflows to accelerate antibody research and therapies

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From Dotmatics 5 May 2022

New model can predict drug-drug interactions based on drug-induced gene expression signatures

Prescriptions for multiple drugs, or polypharmacy, is often recommended for the treatment of complex diseases.

4 May 2022

Discovery could lead to new treatments to minimize cravings in people with addictions

For some people with alcohol use disorder, it might be the sight of a familiar bar or a favorite bottle; for others, it might be the feeling of leaving the office after a stressful day at work or stepping into a crowded party. Most people who struggle with drug or alcohol addiction have particular cues that set off their cravings.

4 May 2022

Drug Discovery News and Research

Further Reading

Novel approach identifies potent drug-like molecules that bind to cancer protein of interest

New method to combat malaria turns the disease against itself

Collaborative effort uncovers a new type of triterpenes

Dr. Paul Brooks is CN Bio's New Chief Business Officer

Insilico Medicine nominates novel preclinical candidate targeting 3CL protease for COVID-19 treatment

Researchers discover osteogenetic oligodeoxynucleotide that promotes bone differentiation

University of Minnesota receives $66 million to establish new antiviral drug discovery center

UNC-Chapel Hill secures $65 million NIH grant for establishing Antiviral Drug Discovery Center

New funding boost to combat antibiotic resistance

New approach to elevate health and well-being by optimizing late-life brain capital

NIH awards $577 million to establish AViDD Centers for Pathogens of Pandemic Concern

A*STAR, NHCS, NUS, and Novo Nordisk partner to study the mechanisms underlying heart failure

bit.bio launches Huntington’s disease human cell model

Dotmatics Biology Solution for Antibody Discovery streamlines data collection and workflows to accelerate antibody research and therapies

New model can predict drug-drug interactions based on drug-induced gene expression signatures

Discovery could lead to new treatments to minimize cravings in people with addictions

MIT researchers develop a smarter method to discover new drugs

Cancer Research UK reveals innovation engine underpinned by £400m portfolio of cutting-edge discovery science

UNIGE scientists develop a novel tool to visualize palmitoylation process in living cells

Dotmatics, previously Insightful Science, set to transform the future of scientific software and data management

Drug Discovery - Second Edition eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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