Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Stress-linked disorders increase the risk of later brain degeneration

A new study published in the journal JAMA Neurology in March 2020 suggests that stress-related disorders increase the risk of later development of dementia and other neurodegenerative disorders.

9 Mar 2020

New toolkit to repair DNA breaks linked to aging, cancer and MND discovered

A new 'toolkit' to repair damaged DNA that can lead to aging, cancer and Motor Neurone Disease has been discovered by scientists at the Universities of Sheffield and Oxford.

9 Mar 2020

Researchers find link between interferon, neuroinflammation and synapse loss in Alzheimer's

When immunologist Dr. Wei Cao joined Baylor College of Medicine three-and-a-half years ago, her first project was to investigate how inflammation contributes to Alzheimer's disease.

5 Mar 2020

Eye movements play functional role in memory retrieval, study shows

In a recent study, scientists at Baycrest's Rotman Research Institute (RRI) found that research participants moved their eyes to determine whether they had seen an image before, and that their eye movement patterns could predict mistakes in memory.

5 Mar 2020

KAIST researchers reveal new strategy to alter neurotoxicity in Alzheimer's disease

It has become evident recently that the interactions between copper and amyloid-β neurotoxically impact the brain of patients with Alzheimer's disease.

3 Mar 2020

Alzheimer's could be detected early using a blood test

Researchers from the ARTFL-LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD) research consortium, have reported that a blood test could soon be an important diagnostic tool in detecting the abnormal proteins deposits in the brain that lead to the progressive and debilitating condition of Alzheimer's disease. The study titled, "Diagnostic value of plasma phosphorylated tau181 in Alzheimer's disease and frontotemporal lobar degeneration," was published in today's issue of the journal Nature Medicine.

2 Mar 2020

Potential genetic test for earlier Alzheimer's diagnosis

A new study published in the journal Epigenetics in February 2020 reports that changes in the methylation status of the Presenilin 1 (PSEN1) gene could help diagnose Alzheimer's disease (AD) earlier. This study shows for the first time that methylation of this gene is a common feature in AD.

1 Mar 2020

Gene therapy regenerates functional new neurons in mouse models of HD

Huntington's disease (HD) is a rare disease characterized by abnormal chorea movement and caused by Huntingtin (Htt) gene mutation and neurodegeneration in a brain area called striatum.

28 Feb 2020

Study shows how cellular filament helps neural stem cells clear damaged, clumped proteins

New research by University of Wisconsin-Madison scientists reveals how a cellular filament helps neural stem cells clear damaged and clumped proteins, an important step in eventually producing new neurons.

28 Feb 2020

Researchers discover glial cells that control stress response, extend lifespan in worms

While many of us worry about proteins aggregating in our brains as we age and potentially causing Alzheimer's disease or other types of neurodegeneration, we may not realize that some of the same proteins are aggregating in our muscles, setting us up for muscle atrophy in old age.

23 Feb 2020

MD Anderson collaborates with Denali Therapeutics to advance novel therapies for neurodegenerative diseases

The University of Texas MD Anderson Cancer Center today announced a strategic research collaboration with Denali Therapeutics Inc. to develop novel therapies for Alzheimer's and other neurodegenerative diseases.

20 Feb 2020

Researchers uncover why Zika virus caused most harmful brain damage to Brazilian newborns

Due to Zika virus, more than 1,600 babies were born in Brazil with microcephaly, or abnormally small heads, from September 2015 through April 2016.

18 Feb 2020

Study reveals how cells remove misfolded proteins from tissues

Researchers in Japan have identified a new quality control system that allows cells to remove damaged and potentially toxic proteins from their surroundings.

18 Feb 2020

Researchers uncover genetic mechanisms that govern brain plasticity

Genetic mechanisms that govern brain plasticity - the brain's ability to change and adapt - have been uncovered by researchers at the University of Birmingham.

18 Feb 2020

Research suggests new approach to block tau pathology in FTLD, Alzheimer's

The protein β-arrestin-2 increases the accumulation of neurotoxic tau tangles, a cause several forms of dementia, by interfering with removal of excess tau from the brain, a new study by the University of South Florida Health Morsani College of Medicine found.

17 Feb 2020

Bilingualism can delay symptoms of dementia, study reveals

A study by York University psychology researchers provides new evidence that bilingualism can delay symptoms of dementia.

13 Feb 2020

Blood test for inflammatory and cell senescence biomarkers may help predict cognitive decline

In order to provide the best medical care for newly diagnosed Parkinson's disease (PD) patients, a method of predicting their cognitive and motor progression, beyond using purely clinical parameters, would have major implications for their management.

11 Feb 2020

Research uncovers protective role of astrocytes in sporadic motor neuron disease

Support cells in the nervous system help protect motor neurons in the early-stages of sporadic motor neuron disease, according to new research from the Crick and UCL.

10 Feb 2020

Clinical trial of two investigational drugs for rare, inherited Alzheimer's yields disappointing results

An international clinical trial evaluating whether two investigational drugs can slow memory loss and cognitive decline in people in the early stages of a rare, inherited form of Alzheimer's disease has yielded disappointing results, an initial analysis of the data has shown.

10 Feb 2020

Researchers receive federal grant to evaluate potential imaging biomarker for Alzheimer's

Researchers at Wake Forest School of Medicine have received a five-year grant worth approximately $2.53 million from the National Institute on Aging to evaluate whether a novel brain-imaging technique can identify Alzheimer's disease in its early stages.

9 Feb 2020

Neurodegeneration News and Research

Further Reading

Stress-linked disorders increase the risk of later brain degeneration

New toolkit to repair DNA breaks linked to aging, cancer and MND discovered

Researchers find link between interferon, neuroinflammation and synapse loss in Alzheimer's

Eye movements play functional role in memory retrieval, study shows

KAIST researchers reveal new strategy to alter neurotoxicity in Alzheimer's disease

Alzheimer's could be detected early using a blood test

Potential genetic test for earlier Alzheimer's diagnosis

Gene therapy regenerates functional new neurons in mouse models of HD

Study shows how cellular filament helps neural stem cells clear damaged, clumped proteins

Researchers discover glial cells that control stress response, extend lifespan in worms

MD Anderson collaborates with Denali Therapeutics to advance novel therapies for neurodegenerative diseases

Researchers uncover why Zika virus caused most harmful brain damage to Brazilian newborns

Study reveals how cells remove misfolded proteins from tissues

Researchers uncover genetic mechanisms that govern brain plasticity

Research suggests new approach to block tau pathology in FTLD, Alzheimer's

Bilingualism can delay symptoms of dementia, study reveals

Blood test for inflammatory and cell senescence biomarkers may help predict cognitive decline

Research uncovers protective role of astrocytes in sporadic motor neuron disease

Clinical trial of two investigational drugs for rare, inherited Alzheimer's yields disappointing results

Researchers receive federal grant to evaluate potential imaging biomarker for Alzheimer's

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