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Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Researchers at Baylor College of Medicine/Texas Children's Cancer Center and collaborating institutions report interim results from a first-in-human phase 1 clinical trial evaluating the safety, antitumor activity and immunological characteristics of a genetically engineered natural killer T (NKT) cell immunotherapy for neuroblastoma, a childhood tumor that most commonly arises in the adrenal gland.

15 May 2023

Newly identified genetic variant provides protection from Alzheimer's disease

A single patient can spark new research questions and provide answers about a disease. And when a new case is identified, investigators can make connections between them that can lead to even more powerful and persuasive ideas about cause and treatment.

15 May 2023

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Intratumoral delivery of an engineered oncolytic virus (DNX-2401) targeting glioblastoma (GBM) cells combined with subsequent immunotherapy was safe and improved survival outcomes in a subset of patients with recurrent GBM, according to results from a multi-institutional Phase I/II clinical trial co-led by researchers at The University of Texas MD Anderson Cancer Center and the University of Toronto.

15 May 2023

Study sheds light on the importance of a subset of microglial cells in cognition and memory

A new study sheds light on the importance of microglia, the immune cells of the brain, in cognition and memory.

15 May 2023

First-in-human clinical trial tests experimental oral drug for removing radioactive contaminants

A first-in-human clinical trial of an experimental oral drug for removing radioactive contaminants from inside the body has begun.

15 May 2023

Placenta plays a more significant role in developing schizophrenia than previously known

More than 100 genes linked to the risk of schizophrenia seem to cause illness because of their role in the placenta rather than in the developing brain, according to a new study led by the Lieber Institute for Brain Development.

15 May 2023

Vascular health management may play role in preserving physical function during aging

Managing cardiovascular disease (CVD) risk factors may play a role in preserving physical function during the aging process, according to new research published today by The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences.

15 May 2023

Researchers develop a computational approach to predict diabetic kidney disease

Researchers from Sanford Burnham Prebys and the Chinese University of Hong Kong have developed a computational approach to predict whether a person with type 2 diabetes will develop kidney disease, a frequent and dangerous complication of diabetes.

15 May 2023

Humanized mouse model for rare genetic disease developed for the first time

Mice with a defected human gene responsible for a rare genetic disease, called congenital adrenal hyperplasia, have been developed for the first time.

15 May 2023

Supercharge your health with carotenoids

This review highlights carotenoids' various biological activities, including antioxidant, anti-tumor, anti-diabetic, anti-aging, and anti-inflammatory effects, with a specific focus on lycopene.

15 May 2023

Study shows AI chatbot provides quality and empathetic answers to patient questions

Are artificial intelligence chatbot assistants capable of providing the same level of quality and empathy as human doctors?

14 May 2023

Pioneering focused ultrasound trial shows promising results for patients with Parkinson’s disease

The findings of a major international trial to test a high-tech, scalpel-free approach to treating movement problems caused by Parkinson’s disease have been published in the prestigious New England Journal of Medicine.

13 May 2023

Maternal cortisol levels during pregnancy linked to language development in children over time

High levels of the stress hormone cortisol during the third trimester of pregnancy may improve speech and language skills in the first 3 years of a child's life, according to research presented at the 25th European Congress of Endocrinology in Istanbul.

13 May 2023

COVID-19 pandemic exacerbated childbirth fear among pregnant people

The COVID-19 pandemic exacerbated fear of childbirth among pregnant people in the U.S., according to a new Dartmouth study.

13 May 2023

Former anabolic steroid users more likely to develop heart disease

Anabolic steroids not only can cause serious side effects during use, such as heart failure and depression, but can continue being harmful years after stopping, according to two studies presented at the 25th European Congress of Endocrinology in Istanbul.

13 May 2023

Long COVID risk may increase with low levels of vitamin D

Long COVID risk has been found to increase with low levels of vitamin D, according to research presented at the 25th European Congress of Endocrinology in Istanbul.

13 May 2023

ER doctors vow to pursue case against envision even in bankruptcy

If Envision Healthcare files for bankruptcy, a group of emergency room doctors would seek permission to continue their federal lawsuit that claims the private equity-backed company is violating California's ban on corporate control of medical practices.

12 May 2023

Medicine News and Research

Phase 1 clinical trial of CAR-NKT cell therapy shows promising results in neuroblastoma patients

Newly identified genetic variant provides protection from Alzheimer's disease

Combination approach is safe, improves survival outcomes in a subset of glioblastoma patients

Study sheds light on the importance of a subset of microglial cells in cognition and memory

First-in-human clinical trial tests experimental oral drug for removing radioactive contaminants

Placenta plays a more significant role in developing schizophrenia than previously known

Vascular health management may play role in preserving physical function during aging

Researchers develop a computational approach to predict diabetic kidney disease

Humanized mouse model for rare genetic disease developed for the first time

Supercharge your health with carotenoids

Study shows AI chatbot provides quality and empathetic answers to patient questions

Pioneering focused ultrasound trial shows promising results for patients with Parkinson’s disease

Maternal cortisol levels during pregnancy linked to language development in children over time

COVID-19 pandemic exacerbated childbirth fear among pregnant people

Former anabolic steroid users more likely to develop heart disease

Long COVID risk may increase with low levels of vitamin D

ER doctors vow to pursue case against envision even in bankruptcy

Newly identified biomarker may predict NSCLC patients' treatment response to chemoimmunotherapy

Patient-derived head and neck cancer organoids could aid the discovery of novel therapies

Using an intracellular toolkit to map organelle bio-geography in stem cells

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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