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Possible therapeutic approach to lowering LDL cholesterol and homocysteine levels

Canadian scientists report that mice genetically altered so as to lack either of the two different pathways through which humans, mice, and other animals provide lipids for high density and low density lipoproteins (HDL and LDL) did not appear to suffer any ill effects. But animals from both groups had markedly lower levels of cholesterol in their blood stream.

14 Jun 2004

Chairman's speech at consultants conference 2004

Put patients first. That's what Mr Reid says. That's fine. Consultants do this every day. We don't need a politician to say it, like it's something we never thought of. When a consultant is working 50 hours a week despite only being paid for 35, that is putting the patient first. When a consultant is operating on an emergency patient in the middle of the night, that is putting the patient first.

12 Jun 2004

Sirolimus-based therapy following early cyclosporine withdrawal improves transplanted kidney structure and function

Kidney histology and function three years after transplantation are better in kidney-transplant patients who remain on sirolimus-based therapy following early withdrawal of cyclosporine than in patients who continue on this calcineurin inhibitor, according to a new study published in the American Journal of Transplantation.

11 Jun 2004

People with extremely early or extremely late sleep times may suffer from Circadian Rhythm Sleep Disorder

You probably know "night owls," those people not ready to fall asleep until the wee hours of the morning. And, you may also know "larks," those early risers who wake before the sun comes up and are ready for bed right after dinner. People with extremely early or extremely late sleep times may suffer from Circadian Rhythm Sleep Disorder (CRSD).

11 Jun 2004

Cholesterol isn’t all bad

Cholesterol gets lots of bad press, and for good reason. An estimated 24 million women and 18 million men have total cholesterol levels of 240 milligrams per deciliter (mg/dL) or higher increasing their risk of heart attack and stroke.

11 Jun 2004

U.S.$2.8 to study a virus associated with respiratory infections

The Center for Emerging Infectious Diseases (CEID), based in the University of Iowa College of Public Health, has been awarded a five-year, $2.8 million grant by the National Institute of Allergy and Infectious Diseases to study a virus associated with respiratory infections.

11 Jun 2004

The mother of four boys with one of the world's rarest illnesses has donated her bone marrow to her eldest son

A mum whose four sons all suffer from a rare life threatening disease yesterday donated her bone marrow to her eldest son Josh. Allison Hartley was found to be a match for 12-year-old Joshua, who has the rare degenerative condition XLP.

11 Jun 2004

African Americans suffer from cardiovascular diseases at a rate about five times higher than the rest of the U.S. population

African Americans suffer from cardiovascular diseases at a rate about five times higher than the rest of the U.S. population. In a new study, scientists may have found a culprit: a serious deficiency of nitric oxide, a small molecule vital in the regulation of blood flow and blood pressure.

11 Jun 2004

Pathogens have the ability to cause late-onset sporadic Alzheimer's disease

The possibility of an infectious etiology of chronic diseases, including Alzheimer’s disease, has long been debated and is difficult to prove.

11 Jun 2004

New treatment significantly improves long-term outlook for breast cancer survivors

An updated analysis from an international clinical trial of the drug letrozole was presented on June 8, 2004 at the American Society of Clinical Oncology annual meeting in New Orleans.

11 Jun 2004

Blood test that can detect amplification of a certain gene found in cells associated with breast cancer

Researchers at UT Southwestern Medical Center at Dallas have developed a blood test that can detect amplification of a certain gene found in circulating cells associated with breast cancer.

10 Jun 2004

Drug commonly used for diabetes might be effective in treating multiple sclerosis

Researchers at the University of Illinois at Chicago are launching a clinical trial to determine whether a drug commonly used for diabetes might be effective in treating multiple sclerosis, an autoimmune disease that affects 350,000 Americans.

10 Jun 2004

Conflicting views on embryonic and adult stem cells complicate research in stem cell therapeutics

Though there has been considerable biological and political debate over the use of embryonic stem cells (ESCs) vs. adult stem cells (ASCs) as therapies for tissue engineering and organ transplants, inherent benefits and drawbacks in both techniques compel them to coexist and complement each other.

10 Jun 2004

Remicade shows improvement in both the arthritis and psoriasis associated with psoriatic arthritis

In this trial, REMICADE provided a 70 percent improvement (as measured by ACR 70) in symptoms of arthritis in nearly one-third of patients, compared with only 2 percent of patients on placebo at 24 weeks.

10 Jun 2004

Higher-than-normal amounts of a selenium-containing enzyme could promote type 2 diabetes

A study by researchers at Cornell University suggests that higher-than-normal amounts of a selenium-containing enzyme could promote type 2 diabetes.

10 Jun 2004

Non-aspirin pain drugs may help men with recurrent prostate cancer

Early results from a University of North Carolina at Chapel Hill School of Medicine study may determine if drugs called Cox-2 inhibitors, a newer type of non-aspirin pain medicine now widely prescribed for arthritis symptoms, may benefit men with recurrent prostate cancer.

10 Jun 2004

Project aimed at eliminating anthrax as a potential weapon for terrorists

La Trobe University scientists are using their own unique peptide 'library' containing a thousand million molecular sequences in a project aimed at eliminating anthrax as a potential weapon for terrorists.

10 Jun 2004

New drugs ease treatment of multiple myeloma

Science is increasingly commuting the death sentence that is a diagnosis of multiple myeloma. A cancer of the plasma cells that primarily strikes the elderly, multiple myeloma has been deadly because patients have been unable to withstand the aggressive treatment necessary to combat it.

10 Jun 2004

Gene that affects alcohol sensitivity

Since one of the basic risk factors for alcoholism is a tolerance to alcohol, researchers have long sought to understand the genetic differences among people that affect their sensitivity to alcohol. So far, scientists have met with little success.

9 Jun 2004

£20 million funding for stem cell research in the UK

Scientists at Oxford will benefit from a share of a £20 million cross-research council investment in stem cell research which was announced last month.

9 Jun 2004

Cell News and Research

Possible therapeutic approach to lowering LDL cholesterol and homocysteine levels

Chairman's speech at consultants conference 2004

Sirolimus-based therapy following early cyclosporine withdrawal improves transplanted kidney structure and function

People with extremely early or extremely late sleep times may suffer from Circadian Rhythm Sleep Disorder

Cholesterol isn’t all bad

U.S.$2.8 to study a virus associated with respiratory infections

The mother of four boys with one of the world's rarest illnesses has donated her bone marrow to her eldest son

African Americans suffer from cardiovascular diseases at a rate about five times higher than the rest of the U.S. population

Pathogens have the ability to cause late-onset sporadic Alzheimer's disease

New treatment significantly improves long-term outlook for breast cancer survivors

Blood test that can detect amplification of a certain gene found in cells associated with breast cancer

Drug commonly used for diabetes might be effective in treating multiple sclerosis

Conflicting views on embryonic and adult stem cells complicate research in stem cell therapeutics

Remicade shows improvement in both the arthritis and psoriasis associated with psoriatic arthritis

Higher-than-normal amounts of a selenium-containing enzyme could promote type 2 diabetes

Non-aspirin pain drugs may help men with recurrent prostate cancer

Project aimed at eliminating anthrax as a potential weapon for terrorists

New drugs ease treatment of multiple myeloma

Gene that affects alcohol sensitivity

£20 million funding for stem cell research in the UK

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